CAS 3051828-81-7

Formula: C30H30N6O5

InChI: InChI=1S/C30H30N6O5/c1-39-28-23(30(38)41-22-5-3-2-4-6-22)15-20(16-31-28)24-7-8-25-26(35-24)27(33-18-32-25)34-21-9-12-36(17-21)29(37)19-10-13-40-14-11-19/h2-8,15-16,18-19,21H,9-14,17H2,1H3,(H,32,33,34)/t21-/m0/s1

InChI key: IKONUSTXITZHRM-NRFANRHFSA-N

SMILES: COC1=C(C=C(C=N1)C2=NC3=C(C=C2)N=CN=C3N[C@H]4CCN(C4)C(=O)C5CCOCC5)C(=O)OC6=CC=CC=C6

PI3Kδ-IN-23

CAS: 3051828-81-7

PI3Kδ-IN-23 (compound A11) is a potent inhibitor of PI3Kδ, with an IC₅₀ of 0.27 nM. It binds to PI3Kδ through covalent interaction with Lys779 and plays a significant role in cancer research.

Formula: C₃₀H₃₀N₆O₅

Colore e forma: Solid

Peso molecolare: 554.596

Ref: TM-T204114