CAS 3054652-58-0

Formula: C48H63NO7

InChI: InChI=1S/C48H63NO7/c1-29-13-14-30(2)36(23-29)55-28-39(51)49-32-12-10-11-31(24-32)25-40(52)56-38-16-17-46(7)37(43(38,3)4)15-18-48(9)41(46)35(50)26-33-34-27-45(6,42(53)54)20-19-44(34,5)21-22-47(33,48)8/h10-14,23-24,26,34,37-38,41H,15-22,25,27-28H2,1-9H3,(H,49,51)(H,53,54)/t34-,37-,38-,41+,44+,45-,46-,47+,48+/m0/s1

InChI key: IWRCQTSSUNJKFR-IUNYWOABSA-N

SMILES: CC1=CC(=C(C=C1)C)OCC(=O)NC2=CC=CC(=C2)CC(=O)O[C@H]3CC[C@]4([C@H](C3(C)C)CC[C@@]5([C@@H]4C(=O)C=C6[C@]5(CC[C@@]7([C@H]6C[C@@](CC7)(C)C(=O)O)C)C)C)C

PPARγ agonist 17

CAS: 3054652-58-0

PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.

Formula: C₄₈H₆₃NO₇

Colore e forma: Solid

Peso molecolare: 766.016

Ref: TM-T206082