CAS 3075162-42-1

PKM2 agonist-1

CAS: 3075162-42-1

PKM2 agonist-1 (Compound D16) is a potent allosteric activator of PKM2, with an AC50 value of 77 nM. It inhibits angiotensin II-induced smooth muscle cell phenotypic transformation, effectively preventing aortic dissection and reducing mortality.

Formula: C₂₄H₂₃N₅O₄S₂

Peso molecolare: 509.6

Ref: TM-T214850