CAS 3075541-07-7

FLT3-IN-40

CAS: 3075541-07-7

FLT3-IN-40 (compound 1) is a type I ATP-competitive FLT3 inhibitor with an IC50 of 16.26 nM. It reduces the autophosphorylation levels of FLT3 and the phosphorylation levels of downstream ERK. FLT3-IN-40 exhibits antiproliferative activity, cell cycle regulation, and apoptosis induction. It is applicable in research related to acute myeloid leukemia.

Formula: C₂₄H₂₂N₆O₂

Peso molecolare: 426.47

Ref: TM-T218483