CAS 321-02-8

Mononucleotide di acido nicotinico

Descrizione:

Mononucleotide di acido nicotinico (NAMN), con il numero CAS 321-02-8, è un nucleotide che gioca un ruolo cruciale nel metabolismo cellulare ed è un precursore del nicotinamide adenina dinucleotide (NAD+), una coenzima essenziale nelle reazioni redox. È composto da un gruppo di acido nicotinico legato a uno zucchero ribosio e a un gruppo fosfato. NAMN si trova tipicamente nei sistemi biologici ed è coinvolto in vari percorsi biochimici, comprese le vie relative alla produzione di energia e alla riparazione del DNA. La sostanza è solubile in acqua, il che facilita le sue funzioni biologiche. La sua struttura consente di partecipare a reazioni di fosforilazione, contribuendo alla sintesi di NAD+ e influenzando processi cellulari come il metabolismo energetico, la segnalazione e le risposte allo stress. Inoltre, Mononucleotide di acido nicotinico ha suscitato interesse nella ricerca relativa all'invecchiamento e ai disturbi metabolici, poiché i livelli di NAD+ sono noti per diminuire con l'età, influenzando la salute e la funzione cellulare. In generale, NAMN è un composto vitale nella biochimica, collegando il metabolismo della vitamina B3 a funzioni cellulari essenziali.

Formula: C₁₁H₁₄NO₉P

InChI: InChI=1S/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/m1/s1

InChI key: InChIKey=JOUIQRNQJGXQDC-ZYUZMQFOSA-N

SMILES: O[C@H]1[C@@H](O[C@H](COP(=O)(O)O)[C@H]1O)[N+]=2C=C(C([O-])=O)C=CC2

Sinonimi:

• 1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carboxylate
• 3-Carboxy-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt
• 3-Pyridinecarboxylic acid, mononucleotide
• 3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium
• 3-carboxy-1-(5-O-phosphonopentofuranosyl)pyridinium
• Deamido nicotinamide ribonucleotide
• Deamido-NMN
• Nicotinate mononucleotide
• Nicotinate ribonucleotide
• Nicotinic acid ribonucleotide
• Nicotinic acid ribotide
• Nicotinic mononucleotide
• Pyridinium, 3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt
• Pyridinium, 3-carboxy-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, inner salt
• Pyridinium, 3-carboxy-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• cyclohexane-1,4-diylbis[N-(2-chlorobenzyl)methanamine] dihydrochloride
• β-Nicotinic acid mononucleotide
• Pyridinium, 3-carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt
• Nicotinic acid mononucleotide
• Pyridinium, 3-carboxy-1-β-D-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• 3-Carboxy-1-β-D-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

CAS: 321-02-8

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

Formula: C₁₁H₁₄NO₉P

Purezza: 99%

Peso molecolare: 335.21

Ref: 54-OR1066774

Nicotinic acid mononucleotide

CAS: 321-02-8

Formula: C₁₁H₁₄NO₉P

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 335.2039

Ref: IN-DA00C98M

Nicotinic acid mononucleotide

CAS: 321-02-8

Nicotinic acid mononucleotide iss a key intermediate in the intracellular synthesis of NAD+, Coenzyme 1), closely associated with cellular metabolism.

Formula: C₁₁H₁₄NO₉P

Purezza: 99.87%

Colore e forma: White Solid

Peso molecolare: 335.2

Ref: TM-T19477

Nicotinic acid mononucleotide

CAS: 321-02-8

Peso molecolare: 335.20

Ref: 7W-GV2930

Nicotinic acid mononucleotide

CAS: 321-02-8

1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

Formula: C₁₁H₁₄NO₉P

Purezza: 99%

Peso molecolare: 335.2

Ref: IN-DG01129151

Nicotinic Acid Mononucleotide

CAS: 321-02-8

Formula: C₁₁H₁₄NO₉P

Peso molecolare: 335.20

Ref: 4Z-N-056032

β-Nicotinic Acid Mononucleotide-d4

Prodotto controllato

CAS: 321-02-8

Stability Hygroscopic
Applications β-Nicotinic Acid Mononucleotide-d4 is the isotope labelled analog of β-Nicotinic Acid Mononucleotide (N429390); a nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.
References Petrelli, R. et al.: Curr. Med. Chem., 18, 1973 (2011); Shibata, K. et al.: J. Chrom. B Biomed. Sci. Appl., 749, 281 (2000); Evans, C. et al.: BMC Chem. Biol., 10, 2 (2010)

Formula: C₁₁H₁₀D₄NO₉P

Purezza: >90%

Colore e forma: Neat

Peso molecolare: 339.23

Ref: TR-N429393

β-Nicotinic Acid Mononucleotide

Prodotto controllato

CAS: 321-02-8

Stability Hygroscopic
Applications A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.
References Petrelli, R. et al.: Curr. Med. Chem., 18, 1973 (2011); Shibata, K. et al.: J. Chrom. B Biomed. Sci. Appl., 749, 281 (2000); Evans, C. et al.: BMC Chem. Biol., 10, 2 (2010);

Formula: C₁₁H₁₄NO₉P

Colore e forma: Neat

Peso molecolare: 335.2

Ref: TR-N429390

β-Nicotinic Acid Mononucleotide

CAS: 321-02-8

Formula: C₁₁H₁₄NO₉P

Peso molecolare: 335.2

Ref: ST-EA-CP-A88111