CAS 328-90-5

Acido 2-idrossi-4-(trifluorometil)benzoico

Descrizione:

Acido 2-idrossi-4-(trifluorometil)benzoico, noto anche come TFBA, è un acido carbossilico aromatico caratterizzato dalla presenza di un gruppo idrossile e di un gruppo trifluorometile su un anello benzenico. La sua formula molecolare è C8H5F3O3 e presenta una struttura di acido benzoico con un gruppo idrossile (-OH) in posizione orto e un gruppo trifluorometile (-CF3) in posizione para. Questo composto è tipicamente un solido cristallino bianco ed è solubile in solventi organici, con solubilità limitata in acqua. Il gruppo trifluorometile conferisce proprietà elettroniche uniche, aumentando la sua acidità e rendendolo un intermediario utile nella sintesi organica, in particolare nello sviluppo di farmaci e agrochimici. Inoltre, il TFBA può mostrare interessanti attività biologiche, rendendolo oggetto di ricerca in chimica medicinale. La sua stabilità in varie condizioni e la reattività con nucleofili contribuiscono ulteriormente alla sua utilità nelle applicazioni sintetiche. Devono essere osservate precauzioni di sicurezza quando si maneggia questo composto a causa della sua potenziale tossicità e impatto ambientale.

Formula: C₈H₅F₃O₃

InChI: InChI=1S/C8H5F3O3/c9-8(10,11)4-1-2-5(7(13)14)6(12)3-4/h1-3,12H,(H,13,14)

InChI key: InChIKey=XMLFPUBZFSJWCN-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC(O)=C(C(O)=O)C=C1

Sinonimi:

• 2,4-Cresotic acid, α,α,α-trifluoro-
• 2-Hydroxy-4-(Trifluoromethyl)Benzoic Acid
• 2-Hydroxy-4-Trifluoromethylbenzoic Acid
• 4-(Trifluoromethy)Salicylic Acid
• 4-(Trifluoromethyl)-2-Hydroxybenzoic Acid
• 4-Trifluoromethyl Salicylic Acid
• 4-Trifluoromethylsalicylic Acid
• 4-Trifluoromethylsalicylicacid
• Benzoic Acid, 2-Hydroxy-4-(Trifluoromethyl)-
• P-Trifluoromethylsalicylicacid
• Rarechem Al Be 1424
• Trifluoromethylsalicylicacid
• p-(Trifluoromethyl)salicylic acid

4-Trifluoromethylsalicylic acid

CAS: 328-90-5

2-Hydroxy-4-(trifluoromethyl)benzoic acid

Formula: C₈H₅F₃O₃

Purezza: 97%

Peso molecolare: 206.12

Ref: IN-DG8328

4-(Trifluoromethyl)salicylic Acid

CAS: 328-90-5

Formula: C₈H₅F₃O₃

Purezza: >98.0%(GC)(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 206.12

Ref: 3B-T2064

4-Trifluoromethylsalicylic acid

CAS: 328-90-5

Formula: C₈H₅F₃O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 206.1187

Ref: IN-DA007ILP

4-Trifluoromethylsalicylic acid

CAS: 328-90-5

4-Trifluoromethylsalicylic acid ,with CAS No. 328-90-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Trifluoromethylsalicylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Formula: C₈H₅F₃O₃

Peso molecolare: 206.12

Ref: TM-PDK0182

Triflusal EP Impurity B (Desacetyl Triflusalic Acid)

CAS: 328-90-5

Formula: C₈H₅F₃O₃

Peso molecolare: 206.12

Ref: 4Z-T-663

Triflusal EP Impurity B

Prodotto controllato

CAS: 328-90-5

Formula: C₈H₅F₃O₃

Colore e forma: Neat

Peso molecolare: 206.12

Ref: 86-MM3414.01

2-Hydroxy-4-(trifluoromethyl)benzoic acid

CAS: 328-90-5

2-Hydroxy-4-(trifluoromethyl)benzoic acid

Formula: C₈H₅F₃O₃

Purezza: 98%

Colore e forma: Solid-Powder

Peso molecolare: 206.1187

Ref: 54-PC1216

Triflusal EP Impurity B-d3 (Desacetyl Triflusalic Acid-d3)

CAS: 328-90-5

Formula: C₈H₂F₃O₃D₃

Peso molecolare: 209.14

Ref: 4Z-T-664

Desacetyl Triflusal

CAS: 328-90-5

Applications The active metabolite of Triflusal; inhibits cardiac hypertrophy in vitro and in vivo by blocking the NF-κB signaling pathway.
References Bayon, Y., et al.: Br. J. Pharmacol., 126, 1359 (1999), Cabrero, A., et al.: Diabetes, 50, 1883 (2001), Cabrero, A., et al.: J. Biol. Chem., 277, 10100 (2002), Culebras, A., et al.: Neurology, 62, 1073 (2004),

Formula: C₈H₅F₃O₃

Colore e forma: Neat

Peso molecolare: 206.12

Ref: TR-D288765

Desacetyl triflusal

CAS: 328-90-5

Triflusal is a drug that inhibits the production of colony-stimulating factor and energy metabolism. It has been shown to have beneficial effects on the liver in vivo. Triflusal also has a chemoattractant protein activity that may be useful for tumor therapy. The pharmacological treatment of triflusal is associated with an increased risk of cancer in humans, which can be attributed to its irreversible inhibition of cyclin D2. Triflusal may have therapeutic potential for treating pain and inflammation, but its use should be limited to patients at low risk for cancer.

Formula: C₈H₅F₃O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 206.12 g/mol

Ref: 3D-FD21130

4-(Trifluoromethyl)salicylic acid

CAS: 328-90-5

Formula: C₈H₅F₃O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 206.12

Ref: 10-F043487

Triflusal EP Impurity B

CAS: 328-90-5

Formula: C₈H₅F₃O₃

Peso molecolare: 206.12

Ref: ST-EA-CP-T186002