CAS 33069-62-4

Paclitaxel

Descrizione:

Paclitaxel, con il numero CAS 33069-62-4, è un prodotto naturale complesso e un agente chemioterapico utilizzato principalmente nel trattamento di vari tipi di cancro, tra cui cancro ovarico, al seno e ai polmoni. È derivato dalla corteccia dell'albero di tasso del Pacifico (Taxus brevifolia) ed è classificato come un taxano. Paclitaxel funziona stabilizzando i microtubuli e prevenendo la loro depolimerizzazione, il che interrompe il normale processo di divisione cellulare, portando infine all'apoptosi nelle cellule tumorali. Il composto è caratterizzato dalla sua struttura unica, che include un sistema ad anello di taxano e diversi gruppi funzionali che contribuiscono alla sua attività biologica. Paclitaxel viene tipicamente somministrato per via endovenosa e ha una solubilità relativamente bassa in acqua, richiedendo spesso formulazioni con solventi come Cremophor EL per uso clinico. I suoi effetti collaterali possono includere neutropenia, reazioni di ipersensibilità e neuropatia periferica. A causa della sua efficacia e meccanismo d'azione, Paclitaxel rimane un pilastro nelle terapie oncologiche, sebbene il suo uso sia spesso accompagnato da un attento monitoraggio e assistenza di supporto.

Formula: C₄₇H₅₁NO₁₄

InChI: InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1

InChI key: InChIKey=RCINICONZNJXQF-MZXODVADSA-N

SMILES: O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)O)=O)C5)[H]

Sinonimi:

• 5β,20-Epoxy-1,2a,4,7β,10β,13α-hexahydroxy-tax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
• 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
• 7,11-Methano-5H-Cyclodeca[3,4]Benz[1,2-B]Oxete Benzenepropanoic Acid Deriv.
• Abi 007
• Abraxane
• Anzatax
• Apealea
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
• Bms 181339-01
• Capxol
• Coroflex Please
• Cremophor-free paclitaxel
• Cyclopax
• Cynviloq
• Cypher select
• Dhp 107
• Ebetaxel
• EmPAC
• EndoTAG 1
• Genaxol
• Genetaxyl
• Genexol
• Genexol-PM
• Ig 001
• Ig 002
• Infinnium
• Intaxel
• Lep-Etu
• Liposome-entrapped paclitaxel easy-to-use
• Mbt 0206
• Mitotax
• Nab-paclitaxel
• Nanotax
• Nanoxel
• Nk 105
• Nsc 125973
• OncoGel
• Onxal
• Oraxol
• Pacitaxel
• Pacliex
• Padexol
• Paxene
• Pazenir
• Plaxicel
• Qw 8184
• Sindaxel
• TAXUS Express
• TAXUS stent
• Tax-11-en-9-one, 5β,20-epoxy-1,2α,4,7β,10β,13α-hexahydroxy-, 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
• TaxAlbin
• Taxal
• Taxol
• Taxol A
• Taxus
• Taxus Liberte
• Tocosol Paclitaxel

Paclitaxel

CAS: 33069-62-4

Formula: C₄₇H₅₁NO₁₄

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 853.92

Ref: 3B-P1632

Paclitaxel, 99.5+%

CAS: 33069-62-4

Paclitaxel, 33069-62-4, also known as Taxol, is an anticancer agent which acts through disruption of microtubule growth. Learn more at Thermo Fisher Scientific.

Formula: C₄₇H₅₁NO₁₄

Purezza: 99.5+%

Colore e forma: White to cream, Crystalline powder or granular

Peso molecolare: 853.92

Ref: 02-J62734

PACLITAXEL NATURAL FOR PEAK IDENTIFICATION CRS

CAS: 33069-62-4

PACLITAXEL NATURAL FOR PEAK IDENTIFICATION CRS

Formula: C₄₇H₅₁NO₁₄

Peso molecolare: 853.9061

Ref: 41-Y0000700

PACLITAXEL CRS

CAS: 33069-62-4

PACLITAXEL CRS

Formula: C₄₇H₅₁NO₁₄

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 853.9061

Ref: 41-Y0000698

PACLITAXEL SEMI-SYNTHETIC FOR SYSTEM SUITABILITY CRS

CAS: 33069-62-4

PACLITAXEL SEMI-SYNTHETIC FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0000739

PACLITAXEL SEMI-SYNTHETIC FOR PEAK IDENTIFICATION CRS

CAS: 33069-62-4

PACLITAXEL SEMI-SYNTHETIC FOR PEAK IDENTIFICATION CRS

Formula: C₄₇H₅₁NO₁₄

Peso molecolare: 853.9061

Ref: 41-Y0000719

Paclitaxel

CAS: 33069-62-4

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₄₇H₅₁NO₁₄

Colore e forma: White Off-White Powder

Peso molecolare: 853.33096

Ref: 45-1491332

Paclitaxel

CAS: 33069-62-4

Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.

Formula: C₄₇H₅₁NO₁₄

Purezza: 98% - 99.92%

Colore e forma: White Solid

Peso molecolare: 853.91

Ref: TM-T0968

Paclitaxel

CAS: 33069-62-4

Paclitaxel

Formula: C₄₇H₅₁NO₁₄

Purezza: ≥98%

Colore e forma: Solid

Peso molecolare: 853.91

Ref: 54-BUP20834

Paclitaxel

CAS: 33069-62-4

Formula: C₄₇H₅₁NO₁₄

Purezza: 97.0 - 102.0 % (anhydrous basis)

Colore e forma: White powder

Peso molecolare: 853.91

Ref: 7W-GA4564

Paclitaxel (Docetaxel EP Impurity F)

CAS: 33069-62-4

Formula: C₄₇H₅₁NO₁₄

Colore e forma: White To Off-White Solid

Peso molecolare: 853.92

Ref: 4Z-P-283

Paclitaxel

Prodotto controllato

CAS: 33069-62-4

Formula: C₄₇H₅₁NO₁₄

Colore e forma: Neat

Peso molecolare: 853.91

Ref: 04-C15839000

Paclitaxel (Standard)

CAS: 33069-62-4

Paclitaxel (Standard) is a reference standard for research and analysis in studies involving Paclitaxel. Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.

Formula: C₄₇H₅₁NO₁₄

Colore e forma: Solid

Peso molecolare: 853.91

Ref: TM-TMSM-3141

Paclitaxel

CAS: 33069-62-4

Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibits MT depolymerization, and changes MT dynamics required for mitosis and cell proliferation. Paclitaxel can induce ototoxicity in rats.

Formula: C₄₇H₅₁NO₁₄

Purezza: 95%~99%

Peso molecolare: 853.918

Ref: BP-BP1055

Paclitaxel (1mg×5)

CAS: 33069-62-4

Formula: C₄₇H₅₁NO₁₄

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 853.92

Ref: 3B-P3207

Paclitaxel

Prodotto controllato

CAS: 33069-62-4

Formula: C₄₇H₅₁NO₁₄

Colore e forma: Neat

Peso molecolare: 853.91

Ref: 86-MM1489.00

Paclitaxel, Taxus brevifolia

CAS: 33069-62-4

M02242 - Paclitaxel, Taxus brevifolia

Formula: C₄₇H₅₁NO₁₄

Purezza: >98%

Colore e forma: Solid, Powder

Peso molecolare: 853.918

Ref: 10-M02242

Paclitaxel from Taxus Mairei

CAS: 33069-62-4

Paclitaxel from Taxus Mairei

Formula: C₄₇H₅₁NO₁₄

Purezza: By hplc: consistent with structure (Typical Value in Batch COA)

Colore e forma: White Solid-Powder

Peso molecolare: 853.90614

Ref: 54-BIP1002

Taxol

CAS: 33069-62-4

Oxygen-heterocyclic compound

Formula: C₄₇H₅₁NO₁₄

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 853.92

Ref: 5G-89806

Paclitaxel

CAS: 33069-62-4

Formula: C₄₇H₅₁NO₁₄

Peso molecolare: 853.92

Ref: ST-EA-CP-P36000