CAS 332950-12-6

ISR activator 3

CAS: 332950-12-6

ISR activator 3 (Compound cc81) is the active metabolite of A8. It activates the integrated stress response (ISR) by binding to RIG-I (KD≈ 0.55 μM) without inducing lipid droplet clearance. Additionally, ISR activator 3 enhances the interferon response under viral mimic signaling. This compound is applicable in studies of neurodegenerative diseases and immune stress.

Formula: C₂₃H₂₁N₃O₃S₂

Peso molecolare: 451.56

Ref: TM-T214641