CAS 33305-77-0

N-(tert-butilossicarbonil)-4-nitro-L-fenilalanina

Descrizione:

N-(tert-butilossicarbonil)-4-nitro-L-fenilalanina, comunemente noto come Boc-4-nitro-L-fenilalanina, è un derivato di amminoacido caratterizzato dalla presenza di un gruppo protettivo tert-butilossicarbonilico (Boc) sul gruppo amminico e di un gruppo nitro nella posizione para dell'anello fenilico. Questo composto è tipicamente utilizzato nella sintesi di peptidi come forma protetta dell'amminoacido L-fenilalanina, consentendo reazioni selettive senza interferire con il gruppo amminico. Il gruppo Boc è stabile in condizioni basiche, ma può essere facilmente rimosso in condizioni acide, rendendolo uno strumento prezioso nella sintesi organica. Il gruppo nitro contribuisce alla polarità del composto e può influenzare la sua reattività e solubilità in vari solventi. Inoltre, la presenza dell'anello fenilico fornisce caratteristiche aromatiche, che possono influenzare le interazioni del composto nei sistemi biologici. In generale, Boc-4-nitro-L-fenilalanina funge da intermediario importante nella sintesi di peptidi e altre molecole bioattive.

Formula: C₁₄H₁₈N₂O₆

InChI: InChI=1S/C14H18N2O6/c1-14(2,3)22-13(19)15-11(12(17)18)8-9-4-6-10(7-5-9)16(20)21/h4-7,11H,8H2,1-3H3,(H,15,19)(H,17,18)/t11-/m0/s1

InChI key: InChIKey=XBQADBXCNQPHHY-NSHDSACASA-N

SMILES: C([C@H](NC(OC(C)(C)C)=O)C(O)=O)C1=CC=C(N(=O)=O)C=C1

Sinonimi:

• (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propanoic acid
• (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic acid
• (S)-2-(tert-Butoxycarbonylamino)-3-(4-nitrophenyl)propanoic acid
• (S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic acid
• 2-(S)-[(tert-Butoxycarbonyl)amino]-3-(4-nitrophenyl)propionic acid
• <span class="text-smallcaps">L</span>-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-4-nitro-
• Alanine, N-carboxy-3-(p-nitrophenyl)-, N-tert-butyl ester, <span class="text-smallcaps">L</span>-
• BOC-L-4-Nitrophe
• Boc-L-4-Nitrophenylalanine
• Boc-Phe(4-NO2)-OH
• D-Phe.otBu.HCl
• N-(tert-Butoxycarbonyl)-4-nitro-<span class="text-smallcaps">L</span>-phenylalanine
• N-(tert-Butyloxycarbonyl)-p-nitro-<span class="text-smallcaps">L</span>-phenylalanine
• N-Boc-p-nitro-<span class="text-smallcaps">L</span>-phenylalanine
• N-[(1,1-Dimethylethoxy)carbonyl]-4-nitro-<span class="text-smallcaps">L</span>-phenylalanine
• N-tert-Butoxycarbonyl-p-nitro-<span class="text-smallcaps">L</span>-phenylalanine
• N-tert-Butoxycarbonyl-p-nitro-L-phenylalanine
• L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-4-nitro-
• N-[(1,1-Dimethylethoxy)carbonyl]-4-nitro-L-phenylalanine
• Alanine, N-carboxy-3-(p-nitrophenyl)-, N-tert-butyl ester, L-

N-(tert-Butoxycarbonyl)-4-nitro-L-phenylalanine

CAS: 33305-77-0

Formula: C₁₄H₁₈N₂O₆

Purezza: >98.0%(T)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 310.31

Ref: 3B-B2232

N-Boc-4-nitro-L-phenylalanine, 95%

CAS: 33305-77-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₄H₁₈N₂O₆

Purezza: 95%

Peso molecolare: 310.31

Ref: 02-H51986

4-Nitro-L-phenylalanine, N-BOC protected

CAS: 33305-77-0

4-Nitro-L-phenylalanine, N-BOC protected

Formula: C₁₄H₁₈N₂O₆

Purezza: >98%

Colore e forma: Light red. Powder

Peso molecolare: 310.30251

Ref: 54-OR14584

Boc-Phe(4-NO2)-OH

CAS: 33305-77-0

Formula: C₁₄H₁₈N₂O₆

Peso molecolare: 310.31

Ref: 7W-GM3581

N-Boc-p-nitro-L-phenylalanine

CAS: 33305-77-0

Formula: C₁₄H₁₈N₂O₆

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 310.3025

Ref: IN-DA003OI4

(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-nitrophenyl)propanoic acid

CAS: 33305-77-0

Formula: C₁₄H₁₈N₂O₆

Purezza: 98%

Peso molecolare: 310.3

Ref: IN-DG20277

BOC-4-Nitro-L-Phenylalanine extrapure, 98%

CAS: 33305-77-0

Formula: C₁₄H₁₈N₂O₆

Purezza: min. 98%

Colore e forma: Yellowish brown, Crystalline powder, Clear

Peso molecolare: 310.31

Ref: SR-14910

Boc-4-Nitro-phenylalanine

CAS: 33305-77-0

M03191 - Boc-4-Nitro-phenylalanine

Formula: C₁₄H₁₈N₂O₆

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 310.306

Ref: 10-M03191

N-Boc-p-nitro-L-phenylalanine

Prodotto controllato

CAS: 33305-77-0

Applications N-Boc-p-nitro-L-phenylalanine is the N-Boc protected form of p-Nitro-L-phenylalanine (N502725, Hydrate) and is a useful synthetic intermediate in the synthesis of Hydroxymelphalan (H939850); an analog of Melphalan (M216900) which is an antineoplastic.
References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)

Formula: C₁₄H₁₈N₂O₆

Colore e forma: Neat

Peso molecolare: 310.3

Ref: TR-B658040