CAS 34031-32-8
:Auranofin
Descrizione:
Auranofin è un composto contenente oro utilizzato principalmente nel trattamento dell'artrite reumatoide. Appartiene alla classe di farmaci noti come sali d'oro, che hanno proprietà anti-infiammatorie. La formula chimica di Auranofin è C20H17AuO9PS, indicando che contiene oro, zolfo, fosforo e diversi componenti organici. Auranofin agisce modulando la risposta immunitaria e inibendo l'attività di alcuni enzimi coinvolti nell'infiammazione. Viene tipicamente somministrato per via orale ed è noto per la sua tossicità relativamente bassa rispetto ad altri composti d'oro. Tuttavia, può comunque causare effetti collaterali, tra cui disturbi gastrointestinali e potenziali reazioni allergiche. Il meccanismo d'azione del composto implica l'inibizione dell'attivazione dei macrofagi e la modulazione della produzione di citochine, contribuendo ai suoi effetti terapeutici. Auranofin ha anche suscitato interesse nella ricerca per le sue potenziali applicazioni oltre l'artrite, comprese le sue proprietà antiparassitarie e anticancro. Come per qualsiasi medicinale, il suo uso deve essere monitorato da professionisti sanitari per gestire efficacemente eventuali effetti avversi.
Formula:C20H34AuO9PS
InChI:InChI=1/C6H15P.Au/c1-4-7(5-2)6-3;/h4-6H2,1-3H3;/q;+1
InChI key:InChIKey=AUJRCFUBUPVWSZ-XTZHGVARSA-M
SMILES:O(C(C)=O)[C@@H]1[C@@H](OC(C)=O)[C@H]([S-][Au+][P](CC)(CC)CC)O[C@H](COC(C)=O)[C@H]1OC(C)=O
Sinonimi:- (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
- 3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydropyran-2-Thiolate
- Aktil
- Auranofina
- Auranofine
- Crisinor
- Crisofin
- Gold Salt
- Gold(+1) Cation
- Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate
- Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-
- Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate
- Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-
- Gold, [1-(thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-
- Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-
- Nsc 321521
- Phosphine, Triethyl-, Gold(1+) Salt (1:1)
- Ridaura
- Ridauran
- Skf 39162
- Skf 39162D
- Triethylphosphonium
- [(Tetra-O-acetyl-β-<span class="text-smallcaps">D</span>-glucopyranosyl)thio](triethylphosphine)gold
- [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold
- [1-(Thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold
- β-<span class="text-smallcaps">D</span>-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex
- β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex
- [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold
- 3,4,5-Triacetyloxy-6-(acetyloxymethyl) oxane-2-thiolate triethylphosphanium
- gold,(1-thio-beta-d-glucopyranose2,3,4,6-tetraacetato-s)(triethylphosphine)
- Gold, [1-(thio-kS)-b-D-glucopyranose2,3,4,6-tetraacetato](triethylphosphine)-
- sk&f39162
- 2,3,4,6-tetra-o-acetyl-1-thio-beta-d-glucopyranosato-s(triethylphosphine)gol
- sk&f39162d
- (1-thio-beta-d-glucopyranosato)-(triethylphosphine)gold2,3,4,6-tetraacetate
- (1-Thio-β-D-glucopyranosato)(triethylphosphine)gold-2，3，4，6-tetraacetate
- gold,(1-thio-beta-d-glucopyranosato-s)(triethylphosphine)-,2,3,4,6-tetraaceta
- AURANOFIN
- sk&fd-39162
- Adtil
- Auranofin, >=98%
- Vedi altri sinonimi
Ordinare per
Purezza (%)
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100
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9 prodotti.
(1-Thio-β-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
CAS:Formula:C20H34AuO9PSPurezza:98%Colore e forma:SolidPeso molecolare:678.4839Ref: IN-DA00382F
1gPrezzo su richiesta1mg52,00€10mg89,00€50mg168,00€100mg271,00€250mgPrezzo su richiesta500mgPrezzo su richiestaAuranofin
CAS:<p>Auranofin (SKF-39162), an antirheumatic, treats rheumatoid arthritis and eases joint pain and stiffness.</p>Formula:C20H34AuO9PSPurezza:97% - 99.01%Colore e forma:White Crystalline Powder SolidPeso molecolare:678.49((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2-Thio)(Triethylphosphine)Gold
CAS:((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2-Thio)(Triethylphosphine)GoldPurezza:98%Peso molecolare:678.5g/molAuranofine
CAS:Formula:C20H34AuO9PSPurezza:≥ 95.0%Colore e forma:White to off-white solidPeso molecolare:678.48Auranofin
CAS:<p>Auranofin is a chrysotherapeutic agent which inhibits histamine release from human basophils. Auranofin is gold-containing salt extensively used in the treatment of rheumatoid arthritis. Auranofin has antimicrobial properties and inhibits the growth of Clostridium difficile more effectively than vancomycin and metronidazole. According to in vitro studies carried out in 2020, auranofin inhibits the replication of coronavirus SARS-CoV-2 and reduces inflammation in human cells.</p>Formula:C20H34AuO9PSColore e forma:White Off-White PowderPeso molecolare:678.49 g/molAuranofin-13C6
CAS:Prodotto controllatoFormula:C14C6H34AuO9PSColore e forma:NeatPeso molecolare:684.44Auranofin
CAS:Prodotto controllato<p>Applications Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kizu, R., et al.: Chem. Pharm. Bull., 41, 1261 (1993), Itokazu, M., et al.: Clin. Ther., 17, 60 (1995), Kean, W.F., et al.: Br. J. Rheumatol., 36, 560 (1997),<br></p>Formula:C20H34AuO9PSColore e forma:NeatPeso molecolare:678.48
