CAS 35661-60-0

Fmoc-leucina

Descrizione:

Fmoc-leucina, o fluorenilmetossicarbonile-leucina, è un derivato dell'aminoacido leucina, comunemente utilizzato nella sintesi di peptidi e nella sintesi di peptidi in fase solida (SPPS). Presenta un gruppo protettivo Fmoc che consente la deprotezione selettiva durante il processo di sintesi. La struttura di Fmoc-leucina include un gruppo fluorenilmetossicarbonile attaccato al gruppo amminico della leucina, che aiuta a stabilizzare l'aminoacido durante la sintesi e previene reazioni indesiderate. Fmoc-leucina è tipicamente un solido bianco a bianco sporco ed è solubile in solventi organici come dimetilformammide (DMF) e dimetilsolfossido (DMSO), ma meno solubile in acqua. Il suo utilizzo nella sintesi di peptidi è favorito grazie alla facilità di rimozione del gruppo Fmoc in condizioni basiche leggere, consentendo l'aggiunta sequenziale di aminoacidi. Inoltre, Fmoc-leucina conserva le proprietà essenziali della leucina, come la sua natura idrofobica, rendendolo prezioso nella progettazione di peptidi con caratteristiche strutturali e funzionali specifiche.

Formula: C₂₁H₂₃NO₄

InChI: InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1

InChI key: InChIKey=CBPJQFCAFFNICX-IBGZPJMESA-N

SMILES: C(OC(N[C@@H](CC(C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid
• (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-4-methylpentanoic acid
• (S)-N-Fmoc-leucine
• 217: PN: US20070042401 PAGE: 29 claimed protein
• 908: PN: WO2006135786 PAGE: 58 claimed protein
• <span class="text-smallcaps">L</span>-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-<span class="text-smallcaps">L</span>-Leucine
• Fmoc-leucine
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-leucine
• N-(9-Fluorenylmethoxycarbonyl)-L-leucine
• N-(9-Fluorenylmethoxycarbonyl)leucine
• N-(Fluorenylmethoxycarbonyl)leucine
• N-FMOC-leucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-leucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucin
• N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-leucina
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-leucine
• N-[(9H-fluorene-9-ylmethoxy)carbonyl]-L-leucine
• Npc 15199
• Nsc 334290
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoate
• Fmoc-L-Leu-OH
• L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-L-Leucine
• (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoate

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine

CAS: 35661-60-0

Formula: C₂₁H₂₃NO₄

Purezza: >98.0%(HPLC)(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 353.42

Ref: 3B-F0295

Fmoc-Leu-OH

CAS: 35661-60-0

M03365 - Fmoc-Leu-OH

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 353.418

Ref: 10-M03365

N-Fmoc-L-leucine, 98%

CAS: 35661-60-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Colore e forma: White, Powder

Peso molecolare: 353.42

Ref: 02-B21040

Fmoc-Leu-OH

CAS: 35661-60-0

Fmoc-Leu-OH (NPC 15199, NSC 334290) showed anti-inflammatory activity. On histologic examination after administration of arachidonic acid, NPC 15199 was found to block the recruitment of neutrophils into the inflammatory site. Fmoc-L-leucine was effective in blocking antigen arthritis in rabbits.

Formula: C₂₁H₂₃NO₄

Purezza: 99.95%

Colore e forma: White

Peso molecolare: 353.42

Ref: 01-4003139

NPC 15199

CAS: 35661-60-0

NPC 15199

Formula: C₂₁H₂₃NO₄

Purezza: 99.5%

Colore e forma: Solid

Peso molecolare: 353.41

Ref: 54-BUP18624

Fmoc-Leu-OH

CAS: 35661-60-0

Formula: C₂₁H₂₃NO₄

Purezza: ≥ 99.0%

Colore e forma: White to almost white powder

Peso molecolare: 353.42

Ref: 7W-GM6129

L-Leucine-d10-N-FMOC

CAS: 1190594-22-9, 35661-60-0

Formula: (CD₃)₂CDCD₂CD(NHFMOC)COOH

Purezza: 98 atom % D

Colore e forma: White Solid

Peso molecolare: 363.48

Ref: 3U-D5492

L-Leucine-d3-N-FMOC(methyl-d3)

CAS: 35661-60-0, 538372-74-6

Formula: CH₃CH(CD₃)CH₂CH(NHFMOC)COOH

Purezza: 99 atom % D

Colore e forma: White Solid

Peso molecolare: 356.44

Ref: 3U-D5733

Fmoc-L-leucine

CAS: 35661-60-0

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 353.4116

Ref: IN-DA00I72W

L-Leucine, FMOC protected

CAS: 35661-60-0

L-Leucine, FMOC protected

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Colore e forma: White Solid

Peso molecolare: 353.41162

Ref: 54-OR0491

Fmoc-Leu-OH

CAS: 35661-60-0

Fmoc-Leu-OH

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Peso molecolare: 353.41

Ref: IN-DG8598

NPC 15199

CAS: 35661-60-0

NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.

Formula: C₂₁H₂₃NO₄

Purezza: 99.93% - 99.94%

Colore e forma: White Solid

Peso molecolare: 353.41

Ref: TM-T8638

Fmoc-Leu-OH

CAS: 35661-60-0

Formula: C₂₁H₂₃NO₄

Peso molecolare: 353.42

Ref: 4Z-L-117005

Fmoc-Leu-OH

CAS: 35661-60-0

Fmoc-Leu-OH is a fatty acid that has been shown to be effective in treating inflammatory diseases such as skin cancer. It has also been shown to have neuroprotective and anti-inflammatory activities, which may be due to its ability to inhibit the nitrite levels in diabetic patients. Fmoc-Leu-OH has been shown to increase insulin sensitivity and decrease insulin resistance in diabetic patients. This drug may also have an effect on cancer by inhibiting the growth of tumor cells and inducing apoptosis.

Formula: C₂₁H₂₃NO₄

Purezza: Min. 98.0 Area-%

Peso molecolare: 353.41 g/mol

Ref: 3D-FLL-1725-PI

Fmoc-Leu-OH

CAS: 35661-60-0

Fmoc-Leu-OH is a fatty acid that contains a hydroxyl group. It is used in the synthesis of polymer drugs, especially sodium salt polymers. The activity of Fmoc-Leu-OH can be reversed with degarelix acetate, an irreversible inhibitor of ns3 protease. In addition to its use as an antidiabetic agent, Fmoc-Leu-OH has been shown to have immunomodulatory effects and antiinflammatory activity. In tumor treatment, Fmoc-Leu-OH has been shown to inhibit the growth of fat cells without affecting normal cells or causing any toxic side effects.

Formula: C₂₁H₂₃NO₄

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 353.41 g/mol

Ref: 3D-FF15776

NPC 15199

CAS: 35661-60-0

Formula: C₂₁H₂₃NO₄

Colore e forma: Solid; [EMD Millipore MSDS]

Peso molecolare: 353.4

Ref: BE-RMCL060005

FMOC-L-Leucine extrapure, 99%

CAS: 35661-60-0

Formula: C₂₁H₂₃NO₄

Purezza: min. 99%

Colore e forma: White to Off white, Crystalline powder

Peso molecolare: 353.40

Ref: SR-99284

Fmoc-Leu-OH

CAS: 35661-60-0

Formula: C₂₁H₂₃NO₄

Peso molecolare: 353.4

Ref: ST-EA-CP-L28033