CAS 3599-32-4
:Verde di indocianina
Descrizione:
Verde di indocianina (ICG) è un colorante sintetico utilizzato principalmente nella diagnostica medica, in particolare in oftalmologia e imaging cardiovascolare. È caratterizzato dal suo colore verde scuro e da una forte assorbimento nella regione dell'infrarosso vicino dello spettro elettromagnetico, rendendolo particolarmente utile per l'imaging a fluorescenza. La struttura chimica dell'ICG include uno scheletro di colorante cianina, che contribuisce alle sue uniche proprietà ottiche. L'ICG è solubile in acqua e ha un profilo di tossicità relativamente basso, il che ne aumenta l'idoneità per le applicazioni cliniche. Dopo la somministrazione, si lega alle proteine plasmatiche, consentendo una visualizzazione efficace del flusso sanguigno e della perfusione tissutale. La sua rapida eliminazione dal flusso sanguigno, principalmente attraverso il fegato, è un'altra caratteristica notevole. Inoltre, l'ICG è utilizzato in varie applicazioni oltre all'imaging, inclusa la valutazione della funzione epatica e la guida di procedure chirurgiche. In generale, le sue proprietà distintive rendono Verde di indocianina uno strumento prezioso sia in contesti diagnostici che terapeutici.
Formula:C43H47N2NaO6S2
InChI:InChI=1/C43H48N2O6S2.Na/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-52(46,47)48)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1/rC43H47N2NaO6S2/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-53(47,48)49)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-54(50,51)52-46/h5-13,18-27H,14-17,28-31H2,1-4H3
InChI key:InChIKey=AANGVCDSLQANGQ-UHFFFAOYSA-N
SMILES:CC1(C)C2=C([N+](CCCCS(=O)(=O)[O-])=C1C=CC=CC=CC=C3N(CCCCS(=O)(=O)O)C4=C(C3(C)C)C=5C(C=C4)=CC=CC5)C=CC=6C2=CC=CC6.[Na]
Sinonimi:- 1H-Benz[e]indolium, 2-[7-[1,1-dimethyl-3-(4-sulfobutyl)benz[e]indolin-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
- 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1)
- 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
- 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt
- 2-{7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]hepta-1,3,5-trienyl}-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium, hydroxyde, sel interne, sel de sodium
- 4,5-Benzoindotricarbocyanine
- 4-[(2Z)-2-[(2Z,4E,6Z)-7-[3,3-dimethyl-1-(4-sulfonatobutyl)benzo[g]indol-1-ium-2-yl]hepta-2,4,6-trienylidene]-3,3-dimethyl-benzo[g]indol-1-yl]butylsulfonyloxysodium
- Cardio Green
- HWD Indocyanine Green
- ICG
- Indocyanin green
- Ir-125
- Natrium-2-[7-[3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolin-2-yliden]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
- Nk 2611
- Nk 2612
- Opthagreen
- Sacarosa, Bruta (De Cana)
- Saccharose, Brut (De Canne)
- So 270
- Sodium 2-(7-(3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz(E)Indolin-2-Ylidene)Hepta-1,3,5-Trien-Y-1-Yl)-3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz[E]Indolinium
- Sodium 2-(7-(3,3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
- Ujoviridin
- Wofaverdin
- sodium 4-(2-{7-[1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indolium-2-yl]hepta-2,4,6-trien-1-ylidene}-1,1-dimethyl-1,2-dihydro-3H-benzo[e]indol-3-yl)butane-1-sulfonate
- 4-(2-[7-[1,1-DIMETHYL-3-(4-SULFO-BUTYL)-1H-BENZO[E]INDOL-2-YL]-HEPTA-2,4,6-TRIENYLIDENE]-1,1-DIMETHYL-BENZO[E]INDOLIUM-3-YL)-BUTANE-1-SULFONIC ACID SODIUM SALT
- )-1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,
- CARDIOGREEN
- BIS-[1-(4-SULFOBUTYL)-3,3-DIMETHYL-4,5-BENZOINDOLINYLIDEN-2]-HEPTAMETHINECYANINE-BETAINE-SODIUM SALT (INDOCYANINEGREEN, CARDIOGREEN)
- FOXGREEN
- IC GREEN
- INDOCYANINE GREEN
- ,innersalt,sodiumsalt(9ci)
- Vedi altri sinonimi
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Indocyanine Green
CAS:Formula:C43H47N2NaO6S2Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:774.97Indocyanine Green
CAS:Synthetic organic coloring matter,nesoiFormula:C43H47N2NaO6S2Colore e forma:Green Brown Blue PowderPeso molecolare:774.27732Cardio-Green
CAS:Cardio-GreenFormula:C43H47N2NaO6S2Purezza:>97%Colore e forma:SolidPeso molecolare:774.96Cardiogreen
CAS:Formula:C43H47N2NaO6S2Purezza:≥ 90.0%Colore e forma:Dark green powderPeso molecolare:774.96Indocyanine green
CAS:Indocyanine greenFormula:C43H47N2NaO6S2Purezza:98.5%Colore e forma:SolidPeso molecolare:774.96Cardiogreen, 95%, USP grade
CAS:Formula:C43H47N2NaO6S2Purezza:90.0 - 105.0 % (dried basis)Colore e forma:Dark green to brown crystalline powderPeso molecolare:774.961H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1)
CAS:Formula:C43H47N2NaO6S2Purezza:95%Colore e forma:SolidPeso molecolare:774.9629Indocyanine Green (~90%)
CAS:Prodotto controllatoFormula:C43H47N2O6S2·NaPurezza:~90%Colore e forma:NeatPeso molecolare:774.96Indocyanine Green >d6
CAS:Prodotto controllatoApplications It is the labeled analogue of Indocyanine Green (I697000), a tricarbocyanine type of dye with infrared absorbing properties that can be used as a diagnostic aid (blood volume determination, cardiac output, hepatic function).
References Papageorgiou, P., et al.: Br. J. Dermatol., 142, 973 (2000), Dreno, B., et al.: Dermatology, 203, 135 (2001), Gollnick, H., et al.: Drugs, 63, 1579 (2003), Seaton, E., et al.: Lancet, 362, 1347 (2003),Formula:C7H14N2OColore e forma:NeatPeso molecolare:NAIndocyanine green
CAS:Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics.Formula:C43H47N2NaO6S2Purezza:98.77%Colore e forma:Brown SolidPeso molecolare:774.963Ref: 4Z-I-134002
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaIndocyanine Green
CAS:Sodium 4-(2-(7-(1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-2(3H)-ylidene)hepta-1,3,5-trien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonateFormula:C43H47N2NaO6S2Purezza:95%Peso molecolare:774.96Indocyanine green
CAS:Indocyanine green is a fluorescent dye with a variety of applications in medical imaging. It has been used to diagnose and evaluate the activity of cancer cells and brain functions. Indocyanine green has also been used as an angiographic agent for diagnosis of solid tumours. In addition, it can be used to evaluate liver function and the blood flow in the brain. The biological properties of indocyanine green have not yet been fully elucidated, but it is known that it binds to hepatocyte-like cells in culture and is found at high levels in human serum. This dye shows fluorescence when bound to DNA or RNA, which indicates its possible use as a molecular probe for detecting carcinoma cells.
Indocyanine green is a STT3B inhibitor and has been shown to prevent α-amanitin toxicity in mice (Wang et al, 2023). This means it could be a possible antidote to poisoning by Amanita, such as death cap mushroom Amanita phalloides, which is the cause of over 90% of fatal mushroom poisoning.Formula:C43H47N2O6S2·NaPurezza:(%) Min. 95%Colore e forma:Green PowderPeso molecolare:774.96 g/mol
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