CAS 372-31-6

Etil 4,4,4-trifluoroacetoacetato

Descrizione:

Etil 4,4,4-trifluoroacetoacetato è un composto organico caratterizzato dal suo gruppo trifluorometil e dal gruppo funzionale estere. È un liquido incolore a giallo pallido con un odore fruttato, comunemente usato nella sintesi organica e come intermediario nella produzione di farmaci e agrochimici. La presenza di tre atomi di fluoro ne aumenta la reattività e la lipofilia, rendendolo un blocco di costruzione prezioso in varie reazioni chimiche, comprese le sostituzioni nucleofile e le reazioni di condensazione. Questo composto è solubile in solventi organici come etanolo ed etere, ma ha una solubilità limitata in acqua a causa della sua natura idrofobica. Etil 4,4,4-trifluoroacetoacetato è anche noto per la sua stabilità in condizioni normali, anche se deve essere maneggiato con cura a causa della potenziale tossicità associata ai composti fluorurati. Devono essere adottate misure di sicurezza adeguate quando si lavora con questa sostanza, incluso l'uso di dispositivi di protezione individuale e lavorare in un'area ben ventilata.

Formula: C₆H₇F₃O₃

InChI: InChI=1S/C6H7F3O3/c1-2-12-5(11)3-4(10)6(7,8)9/h2-3H2,1H3

InChI key: InChIKey=OCJKUQIPRNZDTK-UHFFFAOYSA-N

SMILES: C(C(C(F)(F)F)=O)C(OCC)=O

Sinonimi:

• 1-Ethoxy-4,4,4-trifluorobutane-1,3-dione
• 4,4,4-Trifluoro-3-oxo-butyric acid ethyl ester
• 4,4,4-Trifluoro-3-oxobutanoic acid ethyl ester
• 4,4,4-Trifluoroacetoacetic acid ethyl ester
• Acetoacetic acid, 4,4,4-trifluoro-, ethyl ester
• Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester
• Etfaa
• Ethyl (trifluoroacetyl)acetate
• Ethyl 3-oxo-4,4,4-trifluoroacetoacetate
• Ethyl 3-oxo-4,4,4-trifluorobutanoate
• Ethyl 4,4,4-trifluoro-3-oxobutanoate
• Ethyl 4,4,4-trifluoro-3-oxobutyrate
• Ethyl 4,4,4-trifluoroacetylacetonate
• Ethyl Trifluoroacetoacetate
• Ethyl γ,γ,γ-trifluoroacetoacetate
• Ethyl ω,ω,ω-trifluoroacetoacetate
• Ethyl-4,4,4-trifloro-3-oxo-butanoate
• NSC 42739
• NSC 49750
• Trifluoro acetoacetic acid ethyl ester
• Ethyl-4,4,4-trifluoroacetoacetate

Ethyl 4,4,4-Trifluoroacetoacetate

CAS: 372-31-6

Formula: C₆H₇F₃O₃

Purezza: >98.0%(GC)

Colore e forma: Colorless to Almost colorless clear liquid

Peso molecolare: 184.11

Ref: 3B-T0810

Ethyl trifluoroacetoacetate, 97%

CAS: 372-31-6

Ethyl trifluoroacetoacetate is used as an intermediate in synthetic chemistry. It is also used as an intermediate for agro chemicals and pharmaceuticals. Further, it is used in the preparation of fluorinated 2-thiouracil analogs as antithyroid agents. This Thermo Scientific Chemicals brand product w

Formula: C₆H₇F₃O₃

Purezza: 97%

Colore e forma: Liquid, Clear colorless to pale yellow

Peso molecolare: 184.11

Ref: 02-A13717

Ethyl 4,4,4-trifluoroacetoacetate

CAS: 372-31-6

Ethyl 4,4,4-trifluoroacetoacetate

Formula: C₆H₇F₃O₃

Purezza: 95%

Colore e forma: Colourless Liquid

Peso molecolare: 184.11318

Ref: 54-PC3280

Ethyl 4,4,4-trifluoroacetoacetate

CAS: 372-31-6

Ethyl 4,4,4-trifluoroacetoacetate

Formula: C₆H₇F₃O₃

Purezza: tech

Colore e forma: Liquid

Peso molecolare: 184.11318

Ref: 54-PC49444

Ethyl 4,4,4-trifluoroacetoacetate

CAS: 372-31-6

Formula: C₆H₇F₃O₃

Purezza: 98%

Colore e forma: Liquid

Peso molecolare: 184.1132

Ref: IN-DA0035YJ

Ethyl 4,4,4-trifluoro-3-oxobutanoate

CAS: 372-31-6

Ethyl 4,4,4-trifluoro-3-oxobutanoate

Formula: C₆H₇F₃O₃

Purezza: 96%

Peso molecolare: 184.11

Ref: IN-DG33439

Ethyl 4,4,4-trifluoroacetoacetate

CAS: 372-31-6

Formula: C₆H₇F₃O₃

Purezza: 97%

Colore e forma: Liquid

Peso molecolare: 184.114

Ref: 10-F001234

Ethyl 4,4,4-trifluoroacetoacetate

CAS: 372-31-6

Ethyl 4,4,4-Trifluoroacetoacetate is a compound that is used to synthesize enantiopure compounds. It is prepared by the reaction of p-nitrophenyl phosphate with trifluoroacetic acid in the presence of ethylene diamine and sodium carbonate. The first step in the synthesis is the formation of a hemiacetal from the p-nitrophenyl phosphate and ethylene diamine. This hemiacetal reacts with an amine to form a secondary aminium salt. The second step involves hydrolysis of this aminium salt with sodium carbonate to produce an ester product and ammonium chloride. Finally, addition of trifluoroacetic acid leads to formation of the desired product. Ethyl 4,4,4-trifluoroacetoacetate has been shown to have anti-inflammatory properties that may be due to its ability to inhibit prostaglandin

Formula: C₆H₇F₃O₃

Purezza: Min. 95%

Colore e forma: Clear Liquid

Peso molecolare: 184.11 g/mol

Ref: 3D-FE60064

4,4,4-Trifluoro-3-oxobutanoic Acid Ethyl Ester

Prodotto controllato

CAS: 372-31-6

Applications 4,4,4-Trifluoro-3-oxobutanoic Acid Ethyl Ester is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References He, J.Y., et al.: Biotechnol. J., 2, 260 (2007); Mize, P.D., et al.: Anal. Biochem., 179, 229 (1989);

Formula: C₆H₇F₃O₃

Colore e forma: Neat

Peso molecolare: 184.11

Ref: TR-T792060