CAS 3849-21-6

Etil 2-ciano-2-(idrossimino)acetato

Descrizione:

Etil 2-ciano-2-(idrossimino)acetato, con il numero CAS 3849-21-6, è un composto organico caratterizzato dai suoi gruppi funzionali, tra cui un gruppo ciano e un gruppo idrossimino. Questo composto appare tipicamente come un liquido o solido incolore o giallo pallido, a seconda della sua purezza e forma. È solubile in solventi organici polari, il che facilita il suo utilizzo in varie reazioni chimiche. Etil 2-ciano-2-(idrossimino)acetato è spesso utilizzato nella sintesi organica, in particolare nella preparazione di vari derivati e come intermediario nella sintesi di prodotti farmaceutici e agrochimici. La presenza del gruppo ciano contribuisce alla sua reattività, permettendogli di partecipare a reazioni di addizione nucleofila. Inoltre, il gruppo idrossimino può impegnarsi in tautomerizzazione, influenzando la reattività e la stabilità del composto. Devono essere adottate precauzioni di sicurezza quando si maneggia questa sostanza, poiché può comportare rischi per la salute se ingerita o inalata, e deve essere utilizzato un adeguato equipaggiamento di protezione.

Formula: C₅H₆N₂O₃

InChI: InChI=1/C5H6N2O3/c1-2-10-5(8)4(3-6)7-9/h9H,2H2,1H3/b7-4+

InChI key: InChIKey=LCFXLZAXGXOXAP-UHFFFAOYSA-N

SMILES: C(C(OCC)=O)(C#N)=NO

Sinonimi:

• 2-Cyano-2-(hydroxyimino)acetic acid ethyl ester
• Acetic acid, 2-cyano-2-(hydroxyimino)-, ethyl ester
• Acetic acid, cyano(hydroxyimino)-, ethyl ester
• Ethyl (Hydroxyimino)Cyanoacetate
• Ethyl 2-(Hydroxyimino) Cyanoacetate
• Ethyl 2-(Hydroxyimino)-3-Nitrilopropanoate
• Ethyl 2-cyano-2-(hydroxyimino)acetate
• Ethyl 2-cyano-2-(hydroxyimino)ethanoate
• Ethyl 2-cyano-2-oxidoiminoacetate
• Ethyl 2-cyano-2-oximinoacetate
• Ethyl 2-hydroxyimino-2-cyanoacetate
• Ethyl Cyanoglyoxylate Oxime
• Ethyl Cyanoglyoxylate-2-Oxime
• Ethyl Oximinocyanoacetate
• Ethyl cyanoglyoxalate-2-oxime
• Ethyl cyanoximidoacetate
• Ethyl isonitrosocyanoacetate
• Ethyl α-cyano-α-oximinoacetate
• Ethyl2-cyano-2-oximinoacetate
• Ethyl[Hydroximino]Cyanoacetate
• Ethylcyanoglyoxylate-2-oxime=Ethyloximinocyanoacetate
• Glyoxylic acid, cyano-, ethyl ester, 2-oxime
• Glyoxylic acid, cyano-, ethyl ester, oxime
• Isonitrosocyanoacetic Acid Ethyl Ester
• NSC 137667
• NSC 41021
• NSC 42116
• Oximinocyanoaceticacidethylester
• Oxyma
• Oxyma Pure
• Timtec-Bb Sbb007937
• ethyl (2E)-cyano(hydroxyimino)ethanoate
• ethyl (2Z)-cyano(hydroxyimino)ethanoate
• ETHYL CYANO(HYDROXYIMINO)-ACETATE
• Ethyl cyanoglyoxalate-2-oxime, Ethyl isonitrosocyanoacetate
• 2-Ethyloximinocyanocaetate
• Ethyl cyano(hydroxyimino)acetate, Ethyl cyanoglyoxalate-2-oxime, Ethyl isonitrosocyanoacetate

Ethyl Cyano(hydroxyimino)acetate

CAS: 3849-21-6

Formula: C₅H₆N₂O₃

Purezza: >98.0%(GC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 142.11

Ref: 3B-E0847

Ethyl 2-cyano-2-(hydroxyimino)acetate

CAS: 3849-21-6

Formula: C₅H₆N₂O₃

Purezza: 98.0%

Colore e forma: Solid, Powder or Crystalline Powder or Solid

Peso molecolare: 142.114

Ref: 10-F043278

Ethyl isonitrosocyanoacetate, 97%

CAS: 3849-21-6

This product is a non-explosive alternative to HOBt or HOAt, and allows high peptide coupling rates at low racemization when applied in combination with carbodiimides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label

Formula: C₅H₆N₂O₃

Purezza: 97%

Colore e forma: White to pale cream to pale yellow, Crystals or powder or crystalline powder

Peso molecolare: 142.11

Ref: 02-A12691

Cyano-hydroxyimino-acetic acid ethyl ester (Oxyma)

CAS: 3849-21-6

Highly efficient coupling additive, a safer, non-explosive alternative to HOBt.

Formula: C₅H₆N₂O₃

Purezza: > 99%

Colore e forma: Whitish

Peso molecolare: 142.11

Ref: 01-4019721

Ethyl cyano(hydroxyimino)acetate

CAS: 3849-21-6

Ethyl cyano(hydroxyimino)acetate

Formula: C₅H₆N₂O₃

Purezza: ≥95%

Colore e forma: Pale yellow Solid-Crystals

Peso molecolare: 142.11273

Ref: 54-OR29185

Ethyl (hydroxyimino)cyanoacetate

CAS: 3849-21-6

Formula: C₅H₆N₂O₃

Purezza: ≥ 98.0%

Colore e forma: White to pale yellow crystals or crystalline powder

Peso molecolare: 142.11

Ref: 7W-GX9766

Ethyl 2-cyano-2-(hydroxyimino)acetate

CAS: 3849-21-6

Formula: C₅H₆N₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 142.1127

Ref: IN-DA0034W1

Ethyl Cyano(hydroxyimino)acetate

Prodotto controllato

CAS: 3849-21-6

Applications Ethyl Cyano(hydroxyimino)acetate is used in peptide synthesis and has shown to suppress racemiztion, has high coupling efficiency in both solution and solid phase synthesis and is a non-explosive alternative to 1-hydroxybenzotriazole (HOBt) and 1-hydroxy-7-azabenzotriazole (HOAt).
References Khattab, S.N.: Bull. Chem. Soc. Jpn., 83, 1374 (2010)

Formula: C₅H₆N₂O₃

Colore e forma: Neat

Peso molecolare: 142.11

Ref: TR-E918840

Oxyma

CAS: 3849-21-6

Formula: C₅H₆N₂O₃

Peso molecolare: 142.11

Ref: 4Z-O-131001

Ethyl 2-cyano-2-(hydroxyimino)acetate

CAS: 3849-21-6

Ethyl 2-cyano-2-(hydroxyimino)acetate

Formula: C₅H₆N₂O₃

Purezza: 95%

Peso molecolare: 142.11

Ref: IN-DG20584

Oxyma Pure®

CAS: 3849-21-6

OxymaPure® is a hydrogen bond-based molecular probe that binds to the hydroxamic acid group of bacterial cell walls. It has been shown to have an antibacterial activity against Staphylococcus aureus and Escherichia coli. OxymaPure® is soluble in water, making it suitable for oral administration. The safety profile of OxymaPure® includes studies in rats, indicating that it does not cause any toxic effects at doses up to 2000 mg/kg body weight. OxymaPure® can be synthesized on a solid phase by using carbodiimides as reactive agents and linkers as additive materials. This process is relatively rapid and produces high yields of the desired product.

Formula: C₅H₆N₂O₃

Purezza: Min. 95%

Peso molecolare: 142.12 g/mol

Ref: 3D-OXY-1050-PI

Oxyma

CAS: 3849-21-6

Ethyl isonitrosocyanoacetate, generally known as Oxyma or OxymaPure, is an additive used in amide coupling reactions as a racemisation suppressant. Oxyma is a safe alternative to the explosive HOAt and HOBt and is mainly used in combination with the carbodiimides EDCI, DCC or DIC. Oxyma is stable, can be used in solution, solid-phase and microwave-assisted synthesis, has great capacity to inhibit epimerisation, excellent coupling efficiencies and shows no risk of capping the resin or the peptide upon hydrolysis of the ethyl ester.

Formula: C₅H₆N₂O₃

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 142.11 g/mol

Ref: 3D-FE04090