CAS: 388082-77-7 - Lapatinib Ditosylate

Formula: C₄₁H₄₀ClFN₄O₁₁S₃

InChI: InChI=1S/C29H26ClFN4O4S.C7H8O3S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19;1-6-2-4-7(5-3-6)11(8,9)10/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35);2-5H,1H3,(H,8,9,10)

InChI key: InChIKey=OZDXXJABMOYNGY-UHFFFAOYSA-N

SMILES: O=S(=O)(O)C1=CC=C(C=C1)C.O=S(=O)(C)CCNCC=1OC(=CC1)C=2C=CC3=NC=NC(NC4=CC=C(OCC=5C=CC=C(F)C5)C(Cl)=C4)=C3C2

Sinonimi:

• 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-, 4-methylbenzenesulfonate (1:2)
• 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-, bis(4-methylbenzenesulfonate)
• Benzenesulfonic Acid
• Gw 572016F
• Hydrate
• Lapatinib Ditoyslate
• Lapatinib ditosylate anhydrous
• Lapatinib, Tykerb, GW572016
• N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine bis(4-methylbenzenesulfonate)
• N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6 -[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine h ydrate
• N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
• N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine benzenesulfonate hydrate (1:2:1)
• N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine bis(4-methylbenzenesulfonate)
• Tykerb
• Tykerb N-{3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl}-6-{5-{(2-methylsulfonylethy amino)-methyl]-2-furyl}-quinazolin-4-amine-benzenesulfonic acid

Lapatinib Ditosylate

CAS: 388082-77-7

• Formula: C₄₃H₄₂ClFN₄O₁₀S₃
• Colore e forma: Solid
• Peso molecolare: 925.4608

Lapatinib Ditosylate

CAS: 388082-77-7

Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for …

• Formula: C₂₉H₂₆ClFN₄O₄S·2C₇H₈O₃S
• Purezza: 99.71%
• Colore e forma: Yellow Solid
• Peso molecolare: 925.46

Lapatinib-d4 Ditosylate

CAS: 388082-77-7

• Formula: C₂₉H₂₂D₄ClFN₄O₄SC₇H₈O₃S
• Colore e forma: Light Yellow Solid
• Peso molecolare: 585.08 2 172.20

Lapatinib Ditosylate

CAS: 388082-77-7388082-78-8

• Formula: C₂₉H₂₆ClFN₄O₄SC₇H₈O₃S
• Colore e forma: Yellow Solid
• Peso molecolare: 581.07 2*172.20

Lapatinib Ditosylate

CAS: 388082-77-7

Applications Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. References Kim, T.E., et …

• Formula: C₂₉H₂₆ClFN₄O₄S• 2CH₈O₃S
• Colore e forma: Yellow
• Peso molecolare: 925.46

Lapatinib tosylate anhydrous

CAS: 388082-77-7

Inhibitor of EGFR (ErbB1) and HER2 (ErbB2) receptor tyrosine kinases. Used for sensitization of HER2-overexpressing …

• Formula: C₂₉H₂₆ClFN₄O₄S•(C₇H₈O₃S)₂
• Purezza: Min. 95%
• Colore e forma: Off-White Powder
• Peso molecolare: 925.46 g/mol