CAS 39012-20-9

Picroside II

Descrizione:

Picroside II è un composto glicosidico derivato principalmente dalla radice della pianta *Picrorhiza kurroa*, nota per le sue proprietà medicinali nella medicina tradizionale. È caratterizzato dal suo sapore amaro ed è spesso studiato per i suoi potenziali effetti terapeutici, comprese le attività epatoprotettive, anti-infiammatorie e antiossidanti. La struttura chimica di Picroside II consiste in una porzione di glucosio legata a un'aglicone fenolico, contribuendo alla sua attività biologica. Questo composto è solubile in acqua e solventi organici, rendendolo versatile per varie applicazioni in formulazioni erboristiche e ricerca farmacologica. Inoltre, Picroside II ha suscitato interesse per il suo potenziale ruolo nel trattamento dei disturbi epatici e nel miglioramento della funzione immunitaria. Il suo profilo di sicurezza e efficacia sono oggetto di ricerca in corso, evidenziando l'importanza di comprendere la sua farmacocinetica e i meccanismi d'azione nel contesto della medicina erboristica. In generale, Picroside II rappresenta un composto significativo nello studio dei prodotti naturali e delle loro applicazioni nella salute e nel benessere.

Formula: C₂₃H₂₈O₁₃

InChI: InChI=1/C23H28O13/c1-31-12-6-9(2-3-11(12)26)20(30)34-18-10-4-5-32-21(14(10)23(8-25)19(18)36-23)35-22-17(29)16(28)15(27)13(7-24)33-22/h2-6,10,13-19,21-22,24-29H,7-8H2,1H3/t10?,13-,14?,15-,16+,17-,18?,19?,21?,22+,23?/m1/s1

InChI key: InChIKey=AKNILCMFRRDTEY-UHFFFAOYSA-N

SMILES: C(O)C12C(O1)C(OC(=O)C3=CC(OC)=C(O)C=C3)C4C2C(OC5OC(CO)C(O)C(O)C5O)OC=C4

Sinonimi:

• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 2-(Hexopyranosyloxy)-1A-(Hydroxymethyl)-1A,1B,2,5A,6,6A-Hexahydrooxireno[4,5]Cyclopenta[1,2-C]Pyran-6-Yl 4-Hydroxy-3-Methoxybenzoate
• 2-(beta-D-glucopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxy-3-methoxybenzoate
• Amphicoside II
• Ampicoside
• Kutkin II
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Picroside II
• Vanilloyl catalpol
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-D-glucopyranoside deriv.
• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-Hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
• PICROSID II
• Berberine II
• 6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Picroside a…
• Picroside II, 98%, from Picrorhiza scrophulariiflora Pennell.
• 6'-VANILLOYL CATALPOL
• Picroside II, ≥98% (HPLC)
• Picroside II USP/EP/BP
• AMPHICOSIDE
• PICROSIDE ò
• Picroside-2

Picroside II

CAS: 39012-20-9

Formula: C₂₃H₂₈O₁₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 512.4606

Ref: IN-DA00BYG2

Picroside II

CAS: 39012-20-9

Picroside II

Purezza: ≥98%

Peso molecolare: 512.46g/mol

Ref: 54-BUP13396

Picroside 2

CAS: 39012-20-9

Formula: C₂₃H₂₈O₁₃

Purezza: ≥ 98.0%

Colore e forma: White, off-white or pale yellow powder

Peso molecolare: 512.47

Ref: 7W-GC2669

(1aS,1bS,2S,5aR,6S,6aS)-1A-(Hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)Oxy)-1A,1B,2,5A,6,6A-Hexahydrooxireno[2’,3’:4,5]Cyclopenta[1,2-C]Pyran-6-Yl4-

CAS: 39012-20-9

(1aS,1bS,2S,5aR,6S,6aS)-1A-(Hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)Oxy)-1A,1B,2,5A,6,6A-Hexahydrooxireno[2’,3’:4,5]Cyclopenta[1,2-C]Pyran-6-Yl4-

Purezza: 95%

Peso molecolare: 512.46g/mol

Ref: 54-OR1025805

Picroside II

CAS: 39012-20-9

Formula: C₂₃H₂₈O₁₃

Purezza: >98.0%(HPLC)(qNMR)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 512.46

Ref: 3B-P2594

Picroside II

CAS: 39012-20-9

Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities. It has potent anti-apoptotic activity against renal I/R injury by suppressing the TLR4/NF-κB signaling pathway, it can protect the ischemic kidney against renal fibrosis and improve the neurological function of rats upon cerebral ischemia reperfusion injury. Picroside II enhances nerve growth factor (NGF)-induced neurite outgrowth from PC12D cells by amplifying a down-stream step of MAP kinase in the NGF receptor-mediated intracellular MAP kinase-dependent signaling pathway.

Formula: C₂₃H₂₈O₁₃

Purezza: 95%~99%

Peso molecolare: 512.464

Ref: BP-BP1100

Picroside II

CAS: 39012-20-9

Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.

Formula: C₂₃H₂₈O₁₃

Purezza: 98% - 99.83%

Colore e forma: Solid

Peso molecolare: 512.46

Ref: TM-T2817

Picroside ii

CAS: 39012-20-9

Natural glycoside

Formula: C₂₃H₂₈O₁₃

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 512.47

Ref: 5G-89759

Picroside II

Prodotto controllato

CAS: 39012-20-9

Applications Picroside II similar to Picroside I (P437635), acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis or ischemic injury.
References Wang, Y. et al.: Res. Neuro. Int. J., 488911, 8 (2014); Singh, G. et al.: Phytother. Res., 7, 402 (1993); Chander R. et al.: Biochem. Pharmacol., 7, 190 (1992);

Formula: C₂₃H₂₈O₁₃

Colore e forma: Neat

Peso molecolare: 512.46

Ref: TR-P437640

Picroside 2

CAS: 39012-20-9

Picroside 2 is a natural iridoid glycoside, which is derived from the medicinal plant Picrorhiza kurroa. This bioactive compound is primarily extracted from the roots and rhizomes of the plant, known for its significant therapeutic properties. Picroside 2 functions mainly through its antioxidative and anti-inflammatory mechanisms, offering protection against oxidative stress and mitigating liver damage. By inhibiting various inflammatory mediators and pathways, it contributes to cellular protection and promotes regeneration.

Formula: C₂₃H₂₈O₁₃

Purezza: Min. 95%

Peso molecolare: 512.47 g/mol

Ref: 3D-MP10468

Picroside II

CAS: 39012-20-9

Purezza: 97%

Peso molecolare: 512.153

Ref: 10-F869650