CAS 39012-20-9

Picroside II

Descrizione:

Picroside II è un composto glicosidico derivato principalmente dalla radice della pianta *Picrorhiza kurroa*, nota per le sue proprietà medicinali nella medicina tradizionale. È caratterizzato dal suo sapore amaro ed è spesso studiato per i suoi potenziali effetti terapeutici, comprese le attività epatoprotettive, anti-infiammatorie e antiossidanti. La struttura chimica di Picroside II consiste in una porzione di glucosio legata a un'aglicone fenolico, contribuendo alla sua attività biologica. Questo composto è solubile in acqua e solventi organici, rendendolo versatile per varie applicazioni in formulazioni erboristiche e ricerca farmacologica. Inoltre, Picroside II ha suscitato interesse per il suo potenziale ruolo nel trattamento dei disturbi epatici e nel miglioramento della funzione immunitaria. Il suo profilo di sicurezza e efficacia sono oggetto di ricerca in corso, evidenziando l'importanza di comprendere la sua farmacocinetica e i meccanismi d'azione nel contesto della medicina erboristica. In generale, Picroside II rappresenta un composto significativo nello studio dei prodotti naturali e delle loro applicazioni nella salute e nel benessere.

Formula: C₂₃H₂₈O₁₃

InChI: InChI=1/C23H28O13/c1-31-12-6-9(2-3-11(12)26)20(30)34-18-10-4-5-32-21(14(10)23(8-25)19(18)36-23)35-22-17(29)16(28)15(27)13(7-24)33-22/h2-6,10,13-19,21-22,24-29H,7-8H2,1H3/t10?,13-,14?,15-,16+,17-,18?,19?,21?,22+,23?/m1/s1

InChI key: InChIKey=AKNILCMFRRDTEY-UHFFFAOYSA-N

SMILES: C(O)C12C(O1)C(OC(=O)C3=CC(OC)=C(O)C=C3)C4C2C(OC5OC(CO)C(O)C(O)C5O)OC=C4

Sinonimi:

• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 2-(Hexopyranosyloxy)-1A-(Hydroxymethyl)-1A,1B,2,5A,6,6A-Hexahydrooxireno[4,5]Cyclopenta[1,2-C]Pyran-6-Yl 4-Hydroxy-3-Methoxybenzoate
• 2-(beta-D-glucopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxy-3-methoxybenzoate
• Amphicoside II
• Ampicoside
• Kutkin II
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Picroside II
• Vanilloyl catalpol
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-D-glucopyranoside deriv.
• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-Hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
• PICROSID II
• Berberine II
• 6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Picroside a…
• Picroside II, 98%, from Picrorhiza scrophulariiflora Pennell.
• 6'-VANILLOYL CATALPOL
• Picroside II, ≥98% (HPLC)
• Picroside II USP/EP/BP
• AMPHICOSIDE
• PICROSIDE ò
• Picroside-2

Picroside II

CAS: 39012-20-9

Formula: C₂₃H₂₈O₁₃

Purezza: >98.0%(HPLC)(qNMR)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 512.46

Ref: 3B-P2594

Picroside 2

CAS: 39012-20-9

Formula: C₂₃H₂₈O₁₃

Purezza: ≥ 98.0%

Colore e forma: White, off-white or pale yellow powder

Peso molecolare: 512.47

Ref: 7W-GC2669

Picroside II

CAS: 39012-20-9

Picroside II

Formula: C₂₃H₂₈O₁₃

Purezza: 95%

Peso molecolare: 512.46

Ref: 54-OR1025805

Picroside II

CAS: 39012-20-9

Picroside II

Formula: C₂₃H₂₈O₁₃

Purezza: 98.5%

Peso molecolare: 512.46

Ref: 54-BUP13396

Picroside II

CAS: 39012-20-9

Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities. It has potent anti-apoptotic activity against renal I/R injury by suppressing the TLR4/NF-κB signaling pathway, it can protect the ischemic kidney against renal fibrosis and improve the neurological function of rats upon cerebral ischemia reperfusion injury. Picroside II enhances nerve growth factor (NGF)-induced neurite outgrowth from PC12D cells by amplifying a down-stream step of MAP kinase in the NGF receptor-mediated intracellular MAP kinase-dependent signaling pathway.

Formula: C₂₃H₂₈O₁₃

Purezza: 95%~99%

Peso molecolare: 512.464

Ref: BP-BP1100

Picroside II (Standard)

CAS: 39012-20-9

Picroside II (Standard) is a reference standard for research and analysis in studies involving Picroside II. Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.

Formula: C₂₃H₂₈O₁₃

Peso molecolare: 512.4606

Ref: TM-TMSM-1805

Picroside II

Prodotto controllato

CAS: 39012-20-9

Applications Picroside II similar to Picroside I (P437635), acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis or ischemic injury.
References Wang, Y. et al.: Res. Neuro. Int. J., 488911, 8 (2014); Singh, G. et al.: Phytother. Res., 7, 402 (1993); Chander R. et al.: Biochem. Pharmacol., 7, 190 (1992);

Formula: C₂₃H₂₈O₁₃

Colore e forma: Neat

Peso molecolare: 512.46

Ref: TR-P437640

Picroside II

CAS: 39012-20-9

Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.

Formula: C₂₃H₂₈O₁₃

Purezza: 98% - 99.83%

Colore e forma: Solid

Peso molecolare: 512.4606

Ref: TM-T2817

Picroside II

CAS: 39012-20-9

(1aS,1bS,2S,5aR,6S,6aS)-1a-(Hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxy-3-methoxybenzoate

Formula: C₂₃H₂₈O₁₃

Purezza: 95%

Peso molecolare: 512.46

Ref: IN-DG33504

Picroside II

CAS: 39012-20-9

Natural glycoside

Formula: C₂₃H₂₈O₁₃

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 512.47

Ref: 5G-89759

Picroside-II

CAS: 39012-20-9

Formula: C₂₃H₂₈O₁₃

Peso molecolare: 512.5

Ref: BE-RMT12180

Picroside II

CAS: 39012-20-9

Purezza: 97%

Peso molecolare: 512.153

Ref: 10-F869650

Picroside II

CAS: 39012-20-9

Formula: C₂₃H₂₈O₁₃

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 512.4606

Ref: IN-DA00BYG2