CAS 40216-83-9

Cloridrato di 4-idrossi-L-prolina estere metilico

Descrizione:

Cloridrato di 4-idrossi-L-prolina estere metilico è un derivato della prolina, un amminoacido che gioca un ruolo cruciale nella sintesi proteica e nella formazione del collagene. Questo composto presenta un gruppo idrossile al quarto carbonio dell'anello di prolina, il che contribuisce alle sue proprietà uniche. Come estere metilico, ha un gruppo metossile attaccato all'acido carbossilico, migliorando la sua solubilità nei solventi organici. La forma cloridrato indica che è un sale, il che tipicamente migliora la stabilità e la solubilità nelle soluzioni acquose. Questo composto è spesso utilizzato nella ricerca biochimica e nelle applicazioni farmaceutiche, in particolare negli studi relativi alla sintesi del collagene e come potenziale blocco di costruzione nella sintesi dei peptidi. La sua struttura molecolare consente varie interazioni, rendendolo un composto prezioso nella chimica medicinale. Inoltre, potrebbe mostrare attività biologiche, sebbene gli effetti specifici dipendano dal contesto del suo utilizzo e dai sistemi biologici coinvolti. In generale, Cloridrato di 4-idrossi-L-prolina estere metilico è un composto significativo sia nella chimica sintetica che in quella biologica.

Formula: C₆H₁₁NO₃·ClH

InChI: InChI=1S/C6H11NO3.ClH/c1-10-6(9)5-2-4(8)3-7-5;/h4-5,7-8H,2-3H2,1H3;1H/t4-,5+;/m1./s1

InChI key: InChIKey=KLGSHNXEUZOKHH-JBUOLDKXSA-N

SMILES: C(OC)(=O)[C@@H]1C[C@@H](O)CN1.Cl

Sinonimi:

• (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid methyl ester hydrochloride
• (2S,4R)-Methyl 4-Hydroxypyrrolidine-2-Carboxylate Hydrochloride
• (4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride
• 4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride
• 4-Hydroxy-L-Proline Methyl Ester Hcl
• 4-Hydroxyproline ester hydrochloride
• 4-Hydroxyproline methyl ester hydrochloride
• 4-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Hydroxyproline methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4R)-
• <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, hydrochloride, (4R)-
• <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, hydrochloride, trans-
• H-D-trans-Hyp-OMe.HCl
• H-Hyp-Ome・Hcl
• H-L-Hyp-Ome Hcl
• Hcl.Trans-D-Hyp-Ome
• Hydroxyproline methyl ester hydrochloride
• Hydroxyproline-Ome Hcl
• L-4-Hydroxyproline Methyl Ester Hydrochloride
• L-4-Hydroxyproline Methyl Ester Hydrochloride Salt
• L-4-Trans-Hydroxyproline Methyl Ester Hydrochloride
• L-4-Trans-Hydroxyproline Methyl Ester Hydrochloride Salt
• L-Trans-4-Hydroxyproline Methyl Ester Hydrochloride Salt
• Methyl (2S,4R)-4-Hydroxypyrrolidine-2-Carboxylate Hydrochloride
• Methyl (2S,4R)-4-hydroxy-2-pyrrolidinecarboxylate hydrochloride
• Methyl <span class="text-smallcaps">L</span>-hydroxyprolinate hydrochloride
• Methyl trans-4-hydroxy-<span class="text-smallcaps">L</span>-prolinate hydrochloride
• Proline, 4-hydroxy-, methyl ester, hydrochloride
• Trans-4-Hydroxy-L-Proline Methyl Ester Hydrochloride
• trans-4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride
• trans-4-Hydroxyproline methyl ester hydrochloride
• L-Proline, 4-hydroxy-, methyl ester, hydrochloride, trans-
• L-Proline, 4-hydroxy-, methyl ester, hydrochloride, (4R)-
• L-Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4R)-

trans-4-Hydroxy-L-proline Methyl Ester Hydrochloride

CAS: 40216-83-9

Formula: C₆H₁₁NO₃·HCl

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 181.62

Ref: 3B-H1533

trans-4-Hydroxy-L-proline methyl ester hydrochloride, 98%

CAS: 40216-83-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₁₂ClNO₃

Purezza: 98%

Colore e forma: White, Crystals

Peso molecolare: 181.62

Ref: 02-H51726

H-Hyp-OMe · HCl

CAS: 40216-83-9

Bachem ID: 4002341.

Formula: C₆H₁₁NO₃·HCl

Purezza: > 99%

Colore e forma: White

Peso molecolare: 181.62

Ref: 01-4002341

Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride

CAS: 40216-83-9

Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride

Formula: C₆H₁₁NO₃·ClH

Purezza: ≥95%

Colore e forma: White Solid-Crystals

Peso molecolare: 181.61737

Ref: 54-OR14759

H-Hyp-OMe.HCl

CAS: 40216-83-9

Formula: C₆H₁₂ClNO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 181.6174

Ref: IN-DA003UY3

L-4-Hydroxyproline methyl ester hydrochloride

CAS: 40216-83-9

Formula: C₆H₁₁NO₃HCl

Peso molecolare: 181.62

Ref: 7W-GM2861

L-4-Hydroxyproline Methyl Ester HCl

CAS: 40216-83-9

Formula: C₆H₁₁NO₃·HCl

Peso molecolare: 145.16 36.46

Ref: 4Z-P-166023

trans-4-Hydroxy-L-proline Methyl Ester Hydrochloride

CAS: 40216-83-9

Applications trans-4-Hydroxy-L-proline (H952376) derivative. A natural constituent of animal structural proteins such as collagen and elastin.
References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001)

Formula: C₆H₁₂ClNO₃

Colore e forma: Neat

Peso molecolare: 181.62

Ref: TR-H952395

Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride

CAS: 40216-83-9

Formula: C₆H₁₂ClNO₃

Purezza: 97%

Colore e forma: Solid, Crystalline Powder or Solid

Peso molecolare: 181.62

Ref: 10-F066958

trans-4-Hydroxy-L-proline methyl ester hydrochloride

CAS: 40216-83-9

Trans-4-hydroxy-L-proline methyl ester hydrochloride is a matrix metalloproteinase inhibitor. It inhibits the activity of matrix metalloproteinases, which are enzymes that break down collagen and other proteins in the extracellular matrix. The inhibition of these enzymes leads to a decrease in restenosis, which is the recurrence of artery narrowing after angioplasty or stent placement. Trans-4-hydroxy-L-proline methyl ester hydrochloride has been shown to be effective against chemokine receptors, including CCR5 receptor and chemokines such as TNFα. It also inhibits cytokine production by inhibiting signaling pathways that lead to inflammation and cell proliferation.

Formula: C₆H₁₁NO₃·HCl

Colore e forma: White/Off-White Solid

Peso molecolare: 181.62 g/mol

Ref: 3D-FH24381