CAS 458-37-7

Curcumina

Descrizione:

Curcumina, con il numero CAS 458-37-7, è un composto polifenolico naturale derivato principalmente dal rizoma della pianta di curcuma (Curcuma longa). È noto per il suo vivace colore giallo ed è ampiamente riconosciuto per i suoi potenziali benefici per la salute, comprese le proprietà antinfiammatorie, antiossidanti e anticancro. Curcumina presenta una struttura chimica complessa, caratterizzata dai suoi gruppi diketone e fenolici, che contribuiscono alla sua reattività e attività biologica. È poco solubile in acqua ma solubile in solventi organici, il che può influenzare la sua biodisponibilità nelle applicazioni terapeutiche. Curcumina è stato oggetto di ampie ricerche, esplorando il suo ruolo in varie condizioni di salute, comprese le malattie croniche e i disturbi metabolici. Inoltre, è stato studiato per il suo potenziale utilizzo nei coloranti alimentari e come integratore alimentare. Tuttavia, la sua stabilità può essere influenzata da fattori come il pH e l'esposizione alla luce, che sono considerazioni importanti sia nella ricerca che nelle applicazioni pratiche.

Formula: C₂₁H₂₀O₆

InChI: InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

InChI key: InChIKey=VFLDPWHFBUODDF-FCXRPNKRSA-N

SMILES: C(=C/C(CC(/C=C/C1=CC(OC)=C(O)C=C1)=O)=O)\C2=CC(OC)=C(O)C=C2

Sinonimi:

• (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
• (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• (E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione
• (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-
• 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-
• 1,7-Bis(4-Hidroxi-3-Metoxifenil)Hepta-1,6-Dieno-3,5-Diona
• 1,7-Bis(4-Hydroxy-3-Methoxyphenyl)-1,6-Heptadiene-3,5-Dione
• 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-dien-3,5-dion
• 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
• Biocurcumax
• Br 213
• C Yellow 15
• Colorant E 100
• Curcuma
• Curcuma yellow
• Curcumax
• Curcumin I
• Curcumin W
• Curcumine
• Cureit
• Curouma
• Diferuloylmethane
• E 100 (dye)
• E-100
• E100
• Gelbwurz
• Haidr
• Halad
• Haldar
• Halud
• Hepta-1,6-Diene-3,5-Dione, 1,7-Bis(4-Hydroxy-3-Methoxyphenyl)- (1E,6E)
• INS 100i
• Indian Saffron
• Jianghuangsu
• Kacha Haldi
• Kachs Haldi
• Kiriyasu Oil Yellow U
• Lipocurc
• Longvida
• Merita Earth
• NanoCurc
• Natural Yellow 3
• Natxtra
• Nsc 32982
• Safra D'Inde
• San-Ei Curcumine AL
• San-Ei Gen Curcumine AL
• Souchet
• Terra Merita
• Theracurmin
• Theracurmin CR 011L
• Tumeric Yellow
• Turmeric
• Turmeric (dye)
• Turmeric yellow
• Ukon
• Ukon (dye)
• Vacurin
• Yellow Ginger
• Yellow Root
• Yo-Kin
• trans,trans-Curcumin
• C.I. 75300
• C.I. 75300
• C.I. Natural Yellow 3
• Curcumin

Curcumin (Natural)

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Colore e forma: Light yellow to Brown powder to crystal

Peso molecolare: 368.39

Ref: 3B-C0434

Curcumin (Synthetic)

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Purezza: >97.0%(T)

Colore e forma: Light yellow to Brown powder to crystal

Peso molecolare: 368.39

Ref: 3B-C2302

Curcumin, 95% (total curcuminoid content), from Turmeric rhizome

CAS: 458-37-7

Curcumin is used for boron quantification. It inhibits lipoxygenase and cyclooxygenase. It acts as a dietary supplement and is used in pharmaceutical industry. It acts as a food coloring agent and acts as a food additive. This Thermo Scientific Chemicals brand product was originally part of the Alfa

Formula: C₂₁H₂₀O₆

Purezza: 95%

Colore e forma: Orange-yellow or orange, Powder or crystalline powder

Peso molecolare: 368.39

Ref: 02-B21573

Curcumin

CAS: 458-37-7

Curcumin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₂₀O₆

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 368.39

Ref: 11-4739S

Curcumin

CAS: 458-37-7

Formula: [HOC6H3(OCH3)CH=CHCO]2CH2

Purezza: ≥65% (HPLC)

Colore e forma: powder

Peso molecolare: 368.38

Ref: 23-C1386

Curcumin

CAS: 458-37-7

Coloring matter of vegetable or animal origin

Formula: C₂₁H₂₀O₆

Colore e forma: Orange Yellow Powder

Peso molecolare: 368.12599

Ref: 45-1151855

Curcumin

CAS: 458-37-7

Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.

Formula: C₂₁H₂₀O₆

Purezza: 95% - 98.98%

Colore e forma: Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)

Peso molecolare: 368.38

Ref: TM-T1516

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Purezza: 65%

Colore e forma: Solid

Peso molecolare: 368.3799

Ref: IN-DA0038PG

Curcumin

CAS: 458-37-7

Curcumin

Formula: C₂₁H₂₀O₆

Purezza: 97%

Colore e forma: orange solid

Peso molecolare: 368.38g/mol

Ref: 54-BIC8500

Curcumin, pure, 98%

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Purezza: (HPLC) ≥ 98.0%

Colore e forma: Yellow or orange powder

Peso molecolare: 368.39

Ref: 7W-GP7022

Curcumin

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Colore e forma: Yellow or orange powder

Peso molecolare: 368.39

Ref: 7W-GP8291

Curcumin

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Colore e forma: Orange Solid

Peso molecolare: 368.39

Ref: 4Z-C-691

Curcumin (0.1% in ca. 95% Ethanol)

CAS: 458-37-7

Colore e forma: Light yellow to Brown clear liquid

Ref: 3B-C0435

Curcumin

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Colore e forma: Neat

Peso molecolare: 368.38

Ref: 04-C11780000

Curcumin

CAS: 458-37-7

Curcumin, a polyphenolic compound derived from dietary spice turmeric, possesses diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities, it has effective activity against including cancer, cardio-

Formula: C₂₁H₂₀O₆

Purezza: 95%~99%

Colore e forma: Orange powder

Peso molecolare: 368.385

Ref: BP-BP0421

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

CAS: 458-37-7

Formula: C₂₁H₂₀O₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 368.385

Ref: 10-F358294

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

CAS: 458-37-7

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

Formula: C₂₁H₂₀O₆

Purezza: 96%

Colore e forma: orange to dark orange solid

Peso molecolare: 368.38g/mol

Ref: 54-OR24598

Curcumin

CAS: 458-37-7

Ketone phenol

Formula: C₂₁H₂₀O₆

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 368.39

Ref: 5G-89180

Curcumin

CAS: 458-37-7

Applications A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease. Neuroprotective. Dyes and metabolites.
References Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817 (2005), Johnson, J., et al.: Cancer Lett., 255, 170 (2007), Chem. and Eng. News 90(31), 44 (2012)

Formula: C₂₁H₂₀O₆

Colore e forma: Orange

Peso molecolare: 368.38

Ref: TR-C838500

Curcumin

CAS: 458-37-7

Antioxidant; anti-inflammatory; anti-cancer agent; HSP90 inhibitor

Formula: C₂₁H₂₀O₆

Purezza: Min. 95 Area-%

Colore e forma: Slightly Yellow Powder

Peso molecolare: 368.39 g/mol

Ref: 3D-FC09321