CAS 481-42-5

Plumbagina

Descrizione:

Plumbagina, con il numero CAS 481-42-5, è un composto di naftochinone che si trova naturalmente, derivato principalmente dalle radici della pianta *Plumbago*, in particolare da *Plumbago zeylanica*. È caratterizzato dalla sua apparente cristallina gialla-arancione e ha una formula molecolare di C11H8O3. Plumbagina mostra una gamma di attività biologiche, comprese proprietà antimicrobiche, anticancro e antiossidanti, rendendolo di interesse nella ricerca farmacologica. Si sa che il composto interagisce con vari percorsi cellulari, influenzando potenzialmente l'apoptosi e la proliferazione cellulare. Inoltre, Plumbagina è stato studiato per la sua capacità di inibire alcuni enzimi e il suo ruolo nella medicina tradizionale. La sua solubilità è generalmente maggiore nei solventi organici rispetto all'acqua, il che è una caratteristica comune a molti composti organici. Tuttavia, a causa della sua natura reattiva, Plumbagina può subire ossidazione e altre trasformazioni chimiche, il che può influenzare la sua stabilità e efficacia in varie applicazioni. In generale, Plumbagina rappresenta un composto significativo sia nella chimica dei prodotti naturali che nella ricerca medicinale.

Formula: C₁₁H₈O₃

InChI: InChI=1/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3

InChI key: InChIKey=VCMMXZQDRFWYSE-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=C1C)=C(O)C=CC2

Sinonimi:

• 1,4-Naphthalenedione, 5-hydroxy-2-methyl-
• 1,4-Naphthoquinone, 5-hydroxy-2-methyl-
• 2-Methyl-5-hydroxy-1,4-naphthalenedione
• 2-Methyl-5-hydroxy-1,4-naphthoquinone
• 2-Methyljuglone
• 5-Hydroxy-2-Methylnaphthalene-1,4-Dione
• 5-Hydroxy-2-methyl-1,4-naphthalenedione
• 5-Hydroxy-2-methyl-1,4-naphthoquinone
• NSC 236613
• NSC 688284
• Plumbagin from Plumbago indica
• Plumbagin,95%
• Plumbagine
• Plumbagone
• Plumbagin
• Plumbagin, 99+%
• Ophioxylin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone, Plumbagin
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene, 5-Hydroxy-2-methyl-1,4-naphthoquinone
• PLUMBAGIN(RG)
• PLUMBAGIN PRACTICAL GRADE
• SPECS AP-782/41885488
• RARECHEM BW GA 0426
• 5-hydroxy-2-methyl-4-naphthoquinone
• plumbapin
• 5-HYDROXY-2-METHYL-1,4-NAPTHOQUINONE
• Plumbagin (natural)
• 1,4-Dihydro-1,4-dioxo-5-hydroxy-2-methylnaphthalene
• PLANT STEROLS KIT
• 5-hydroxy-2-methyl-4-naphthalenedione
• PLUMBAGIN FROM FROM PLUMBAGO INDICA
• PLUMBAGAN

Plumbagin

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purezza: >98.0%(T)(HPLC)

Colore e forma: Orange to Brown powder to crystal

Peso molecolare: 188.18

Ref: 3B-P1139

Plumbagin

CAS: 481-42-5

Plumbagin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₁H₈O₃

Purezza: (HPLC) ≥90%

Colore e forma: Powder

Peso molecolare: 188.18

Ref: 11-0444

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

5-Hydroxy-2-methylnaphthalene-1,4-dione

Formula: C₁₁H₈O₃

Purezza: 95%

Colore e forma: Orange Solid

Peso molecolare: 188.17942

Ref: 54-OR1174

5-Hydroxy-2-methylnaphthalene-1,4-dione

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 188.1794

Ref: IN-DA003TTF

Plumbagin

CAS: 481-42-5

Plumbagin

Formula: C₁₁H₈O₃

Purezza: ≥98%

Peso molecolare: 188.18

Ref: 54-BUP11118

Plumbagin

CAS: 481-42-5

Formula: C₁₁H₈O₃

Peso molecolare: 188.18

Ref: 7W-GL1138

Plumbagin (Standard)

CAS: 481-42-5

Plumbagin (Standard) is a reference standard for research and analysis in studies involving Plumbagin. Plumbagin (Plumbaein) is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. It is also commonly found in the carnivorous plant genera Drosera and Nepenthes. It is also a component of the black walnut drupe.

Formula: C₁₁H₈O₃

Colore e forma: Solid

Peso molecolare: 188.18

Ref: TM-TMSM-2374

plumbapin

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purezza: 95%~99%

Peso molecolare: 188.182

Ref: BP-BP1113

Plumbagin

CAS: 481-42-5

Plumbagin, a yellow dye from naphthoquinone, is isolated from Plumbago and found in Drosera, Nepenthes, and black walnut drupe.

Formula: C₁₁H₈O₃

Purezza: 99.7% - 99.95%

Colore e forma: Red Solid

Peso molecolare: 188.18

Ref: TM-T2841

Plumbagin

CAS: 481-42-5

Plumbagin

Formula: C₁₁H₈O₃

Purezza: By hplc: 99.4% by area (210nm) (Typical Value in Batch COA)

Colore e forma: Solid

Peso molecolare: 188.17941

Ref: 54-BIDF1037

Plumbagin

CAS: 481-42-5

Quinone

Formula: C₁₁H₈O₃

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 188.18

Ref: 5G-80267

Plumbagin

CAS: 481-42-5

Applications Plumbagin induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Formula: C₁₁H₈O₃

Colore e forma: Neat

Peso molecolare: 188.18

Ref: TR-P627000

Plumbagin

CAS: 481-42-5

Plumbagin is a quinonoid compound, which is a secondary metabolite found in the roots of Plumbago species. This compound is characterized by its naphthoquinone structure, which is responsible for its diverse biological activities. Plumbagin exerts its effects primarily through the generation of reactive oxygen species (ROS), modulation of cellular signaling pathways, and inhibition of specific enzyme functions, such as topoisomerases. These actions result in the modulation of cell proliferation, apoptosis, and inflammation, making Plumbagin a compound of interest for various biomedical applications.

Formula: C₁₁H₈O₃

Purezza: Min. 95%

Colore e forma: Orange Powder

Peso molecolare: 188.18 g/mol

Ref: 3D-FP13778

Plumbagin

CAS: 481-42-5

5-Hydroxy-2-methylnaphthalene-1,4-dione

Formula: C₁₁H₈O₃

Purezza: 98%

Peso molecolare: 188.18

Ref: IN-DG148397

5-Hydroxy-2-methyl-[1,4]naphthoquinone

CAS: 481-42-5

Formula: C₁₁H₈O₃

Purezza: 98%

Colore e forma: No data available.

Peso molecolare: 188.182

Ref: 10-F032384

Plumbagin-d3

Prodotto controllato

CAS: 481-42-5

Applications Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

Formula: C₁₁H₅D₃O₃

Colore e forma: Neat

Peso molecolare: 191.2

Ref: TR-P627002