CAS 50-36-2

Cocaina

Descrizione:

Cocaina, con il numero CAS 50-36-2, è un potente stimolante e anestetico locale derivato dalle foglie della pianta di coca, Erythroxylum coca. È classificato come un alcaloide tropano e ha una struttura chimica complessa, caratterizzata da un telaio biciclico che include un atomo di azoto. Cocaina è noto per la sua capacità di bloccare il riassorbimento dei neurotrasmettitori, in particolare dopamina, norepinefrina e serotonina, portando a livelli aumentati di queste sostanze chimiche nel cervello, contribuendo ai suoi effetti euforici. Nella sua forma pura, Cocaina appare come una polvere cristallina bianca o come un cristallo solido noto come "crack" quando lavorato. È altamente addictivo e ha un alto potenziale di abuso, portando a vari rischi per la salute, inclusi problemi cardiovascolari ed effetti neurologici. Cocaina è anche utilizzato in contesti medici come anestetico locale, in particolare in alcuni tipi di chirurgia oculare, grazie alle sue proprietà vasocostrittrici. Tuttavia, il suo uso ricreativo è illegale in molti paesi ed è classificato come sostanza controllata di Classe II negli Stati Uniti.

Formula: C₁₇H₂₁NO₄

InChI: InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1

InChI key: InChIKey=ZPUCINDJVBIVPJ-LJISPDSOSA-N

SMILES: C(OC)(=O)[C@@H]1[C@@]2(N(C)[C@](C[C@@H]1OC(=O)C3=CC=CC=C3)(CC2)[H])[H]

Sinonimi:

• (-)-Cocaine
• (R)-Cocaine
• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester)
• 1αH,5αH-Tropane-2β-carboxylic acid, 3β-hydroxy-, methyl ester, benzoate (ester)
• 2β-Carbomethoxy-3β-(benzoyloxy)tropane
• 3β-Hydroxy-2β-tropanecarboxylic acid methyl ester benzoate (ester)
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, [1R-(exo,exo)]-
• <span class="text-smallcaps">L</span>-Cocaine
• Benzoylmethylecgonine
• Cocain
• Cocaina
• Ecgonine methyl ester benzoate (ester)
• Neurocaine
• l-Cocaine
• Bernice [Street Name]
• "C" Carrie
• Jam
• Star-spangled powder
• Cocaine [BAN]
• Dama blanca
• Gold dust [Street Name]
• Green gold
• UNII-I5Y540LHVR
• Blow [Street Name]
• methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
• Bernies
• Nose candy
• Pimp's drug
• Coke
• 1-alpha-H,5-alpha-H-Tropane-2-beta-carboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate
• Toot [Street Name]
• Eritroxilina
• 2-beta-Carbomethoxy-3-beta-benzoxytropane
• 2beta-Carbomethoxy-3beta-benzoxytropane
• Erytroxylin
• Star dust
• Kokayeen
• Cholly
• Corine
• 1-Cocaine
• Crack cocaine
• 3-(Benzoyloxy)-8-methyl-8-azabicyclo-(3.2.1)octane-2-carboxylic acid methyl ether
• 3beta-Hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylic acid methyl ester benzoate
• 2-beta-Tropanecarboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester)
• Burese
• DEA No. 9041
• Kokan
• Cocaine, l-
• 3-Tropanylbenzoate-2-carboxylic acid methyl ester
• (1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate
• 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R,2R,3S,5S)-
• Girl [Street Name]
• Rock [Street Name]
• Crack
• Snow
• White girl or lady
• Kokain
• Leaf
• HSDB 6469
• Happy trails
• Methyl 3-beta-hydroxy-1-alpha-H,5-alpha-H-tropane-2-beta-carboxylate benzoate (ester)
• Happy dust [Street Name]
• Methyl 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester)
• Methyl Benzoylecgonine
• Lady [Street Name]
• Flake [Street Name]

Cocaine 0.1 mg/ml in Acetonitrile

Prodotto controllato

CAS: 50-36-2

Colore e forma: Single Solution

Ref: 61-AMP1345.05-12

Cocaine

Prodotto controllato

CAS: 50-36-2

Colore e forma: Neat

Ref: 61-FOR1345.05

Cocaine, 1mg/ml in Acetonitrile

Prodotto controllato

CAS: 50-36-2

Colore e forma: Single Solution

Ref: LP-COC-156-FB-1LA

Cocaine

Prodotto controllato

CAS: 50-36-2

Colore e forma: Neat

Ref: LP-COC-156-FB-10

Cocaine 1.0 mg/ml in Acetonitrile

Prodotto controllato

CAS: 50-36-2

Colore e forma: Single Solution

Ref: 61-AMP1345.05-11

L-Cocaine

Prodotto controllato

CAS: 50-36-2

Applications L-Cocaine, inhibits the dopamine, norepinephrine, and serotonin transporters. Unlike amphetamines, it has no effect on catecholamine release. Controlled substance. Anesthetic (local).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blakely, R.D., et al.: Curr. Opin. Neurobiol., 10, 328 (2000); Cowell, R. M., et al.: Eur. J. Pharmacol., 389, 59 (2000); Fleckenstein, A.E., Eur. J. Pharmacol., 406, 1 (2000), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003);

Formula: C₁₇H₂₁NO₄

Colore e forma: Neat

Peso molecolare: 303.35

Ref: TR-C633495

L-Cocaine (1 mg/ml in Methanol)

Prodotto controllato

CAS: 50-36-2

Formula: C₁₇H₂₁NO₄

Colore e forma: Single Solution

Peso molecolare: 303.35

Ref: TR-KIT2480

Cocaine

Prodotto controllato

CAS: 50-36-2

Cocaine is a small-molecule drug that acts as an indirect agonist to the neurotransmitter dopamine, which is involved in reward and motivation. Cocaine binds to the response element in the promoter region of the gene for the enzyme human erythrocyte membrane protein band 3 (hEPB3). This binding inhibits transcription of hEPB3 mRNA by preventing RNA polymerase from reading through to the start codon. Cocaine also prevents reuptake of catecholamines, which prolongs their effects on postsynaptic cells. Cocaine has been used as a pharmacological treatment for attention deficit hyperactivity disorder, although it is not currently approved by the FDA for this use. The physiological effects of cocaine are similar to those seen with other stimulants such as amphetamine and methyl ethylamphetamine. These include increased heart rate and blood pressure, anxiety, insomnia, paranoia, anorexia, and reduced pain sensitivity.

Formula: C₁₇H₂₁NO₄

Purezza: Min. 95%

Peso molecolare: 303.35 g/mol

Ref: 3D-FC111889