CAS 508233-74-7

Vortioxetina

Descrizione:

Vortioxetina è un farmaco antidepressivo utilizzato principalmente per trattare il disturbo depressivo maggiore. È classificato come un modulatore e stimolatore della serotonina, il che significa che influenza vari recettori della serotonina nel cervello, aumentando i livelli e l'attività della serotonina. La formula chimica di Vortioxetina è C18H22N2S e presenta una struttura unica che include un anello fenilico, un gruppo piperazina e un anello di tiofene. Questo composto mostra un meccanismo d'azione duale: non solo inibisce il riassorbimento della serotonina, ma agisce anche come agonista o antagonista su specifici recettori della serotonina, contribuendo ai suoi effetti terapeutici. Vortioxetina è generalmente ben tollerato, con un profilo di effetti collaterali che può includere nausea, stitichezza e disfunzione sessuale. La sua farmacocinetica indica che ha una emivita relativamente lunga, consentendo una somministrazione una volta al giorno. Come per qualsiasi farmaco, è essenziale che i pazienti consultino professionisti sanitari per consigli personalizzati e monitoraggio durante il trattamento.

Formula: C₁₈H₂₂N₂S

InChI: InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3

InChI key: InChIKey=YQNWZWMKLDQSAC-UHFFFAOYSA-N

SMILES: S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3

Sinonimi:

• 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
• 1-(2-(2.4-Dimeethylphenylthio)Pheny1) Piperazine
• 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine
• Brintellix
• Lu AA 21004
• Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-
• Trintellix
• Vortioxetine
• Vortioxetine 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
• Vortioxetine(Lu AA21004)
• Trintellix (vortioxetine)
• Vortioxetine, >=99%
• 1-(2-((2,4-DIMETHYLPHENYL)THIO)PHENYL)PIPERAZINE-HCL

Lu AA 21004

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Purezza: >95.0%(HPLC)(T)

Peso molecolare: 298.45

Ref: 3B-V0200

Vortioxetine

CAS: 508233-74-7

Vortioxetine

Formula: C₁₈H₂₂N₂S

Purezza: 98%

Peso molecolare: 298.45

Ref: 54-OR1028064

Vortioxetine

CAS: 508233-74-7

Vortioxetine

Formula: C₁₈H₂₂N₂S

Purezza: 99.5%

Colore e forma: Solid

Peso molecolare: 298.45

Ref: 54-BUP15037

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Colore e forma: Off-White Solid

Peso molecolare: 298.45

Ref: 4Z-V-043001

Vortioxetine (Standard)

CAS: 508233-74-7

Vortioxetine (Standard) is a reference standard for research and analysis in studies involving Vortioxetine. Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.

Formula: C₁₈H₂₂N₂S

Peso molecolare: 298.45

Ref: TM-TMSM-3548

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Colore e forma: Neat

Peso molecolare: 298.45

Ref: 86-MM3264.00

N-Nitroso-Vortioxetine-D8

Prodotto controllato

CAS: 508233-74-7, 960203-27-4

Formula: C₁₈H₁₃D₈N₃OS

Colore e forma: Neat

Peso molecolare: 335.49

Ref: TR-N991171

Vortioxetine Hydrobromide-D8

Prodotto controllato

CAS: 508233-74-7, 960203-27-4

Applications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)

Formula: C₁₈D₈H₁₄N₂S·BrH

Colore e forma: Neat

Peso molecolare: 387.407

Ref: TR-V766002

Vortioxetine

Prodotto controllato

CAS: 508233-74-7

Applications Vortioxetine can be used in biological study of effectiveness of long term vortioxetine treatment of patients with major depressive disorder.
References Vieta, E., et al.: Eur Neuropsychopharm (2017)

Formula: C₁₈H₂₂N₂S

Colore e forma: Neat

Peso molecolare: 298.45

Ref: TR-V760100

1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine

CAS: 508233-74-7

1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine

Formula: C₁₈H₂₂N₂S

Purezza: 98%

Peso molecolare: 298.45

Ref: IN-DG224799

Vortioxetine

CAS: 508233-74-7

Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders.

Formula: C₁₈H₂₂N₂S

Purezza: 99.34% - 99.78%

Colore e forma: White Solid

Peso molecolare: 298.45

Ref: TM-T2395

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Peso molecolare: 298.45

Ref: ST-EA-CP-V36000

Vortioxetine

Prodotto controllato

CAS: 508233-74-7

Vortioxetine is a serotonin modulator and reuptake inhibitor which appears to be much more potent on serotonin reuptake inhibition and 5-HT3 receptor antagonism than other interactions with the 5-HT receptor family. This drug binds selectively to 5-HT receptors and inhibits the activity of serotonin reuptake transporters on presynaptic neurons, thereby increasing serotonin concentrations in the brain. It is used for the treatment of major depressive disorder (MDD)and has also been shown to be effective against depression-related symptoms such as sleep disturbances, appetite disturbance, and weight change. Vortioxetine has also been demonstrated to suppress glioblastoma in both ex vivo human tissue samples and in mice. This may indicate vortioxetine signalling cascade activation supresses cancer cell division, and could constitute an effective part of a treatment regime for glioblastoma patients.

Formula: C₁₈H₂₂N₂S

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 298.45 g/mol

Ref: 3D-FD58721

Vortioxetine-[d8] 2HBr

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Peso molecolare: 298.4

Ref: BE-MD-7725

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Peso molecolare: 298.4

Ref: BE-RMCV100000

Vortioxetine in Methanol

CAS: 508233-74-7

Methanol

Formula: C₁₈H₂₂N₂S

Peso molecolare: 298.4

Ref: BE-MU-7725YM-1000

Vortioxetine

CAS: 508233-74-7

Formula: C₁₈H₂₂N₂S

Peso molecolare: 298.4

Ref: BE-MU-7725