CAS 51-48-9

(-)-Tiroxina

Descrizione:

(-)-Tiroxina, noto anche come L-tiroxina o T4, è un ormone prodotto dalla ghiandola tiroidea che svolge un ruolo cruciale nella regolazione del metabolismo, della crescita e dello sviluppo nel corpo. È un derivato tetraiodato dell'aminoacido tirosina, caratterizzato dalla presenza di quattro atomi di iodio nella sua struttura. La formula chimica di (-)-Tiroxina è C15H11I4N0 e ha un peso molecolare di circa 776,87 g/mol. Questo composto si trova tipicamente come una polvere cristallina bianca o bianco sporco ed è solubile in acqua e alcol, ma meno solubile nei solventi organici. (-)-Tiroxina funziona legandosi ai recettori degli ormoni tiroidei, influenzando l'espressione genica e i processi metabolici. È comunemente usato in contesti clinici per trattare l'ipotiroidismo e altri disturbi legati alla tiroide. La sua attività è monitorata da vicino, poiché sia la carenza che l'eccesso possono portare a problemi di salute significativi. Il numero CAS 51-48-9 identifica univocamente questo composto nelle banche dati chimiche, facilitando la ricerca e la conformità normativa.

Formula: C₁₅H₁₁I₄NO₄

InChI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1

InChI key: InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I

Sinonimi:

• (-)-Thyroxine
• 3,3',5,5'-Tetraiodo-L-thyronine
• 3,3′,5,5′-Tetraiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,5,3',5'-Tetraiodothyronine
• 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine
• <span class="text-smallcaps">L</span>-T₄
• <span class="text-smallcaps">L</span>-Thyroxin
• <span class="text-smallcaps">L</span>-Thyroxine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl]Alanine
• DL-thyroxin
• DL-thyroxine
• DL-tiroxina
• Henning
• L-3,5,3',5'-Tetraiodothyronine
• L-T4
• L-Thyroxin
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Levothyroxine
• Levotiron
• Nsc 36397
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosin
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodotyrosine
• O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
• SK&amp;F 1-6528
• T4
• T4(Hormone)
• T₄
• T₄ (hormone)
• THX
• Tetraiodothyronine
• Thyrax
• Thyreoideum
• Thyroxin
• Thyroxinal
• Thyroxine, <span class="text-smallcaps">L</span>-

Levothyroxine

CAS: 51-48-9

Amino-acid derivatives

Formula: C₁₅H₁₁I₄NO₄

Colore e forma: Yellow Off-White Crystalline Powder

Peso molecolare: 776.6867

Ref: 45-1365000

L-Thyroxine Sodium Salt Pentahydrate

CAS: 51-48-9, 55-03-8, 6106-07-6

Formula: C₁₅H₁₀I₄NNaO₄·5H₂O

Purezza: >98.0%(T)

Colore e forma: White to Yellow to Orange powder to crystal

Peso molecolare: 888.94

Ref: 3B-T0245

L-Thyroxine, 98%

CAS: 51-48-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₅H₁₁I₄NO₄

Purezza: 98%

Colore e forma: Powder, Pale cream to cream

Peso molecolare: 776.87

Ref: 02-J62606

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Formula: C₁₅H₁₁I₄NO₄

Purezza: >97%

Colore e forma: Solid

Peso molecolare: 776.87

Ref: 54-OR1030066

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Formula: C₁₅H₁₁I₄NO₄

Purezza: ≥95%

Peso molecolare: 776.87

Ref: 54-BUP17744

L-Thyroxine

CAS: 51-48-9

L-Thyroxine, major thyroid hormone, is made by iodinating tyrosine and coupling it in thyroglobulin, then secreted into blood.

Formula: C₁₅H₁₁I₄NO₄

Purezza: 97.63% - 99.56%

Colore e forma: Crystals Solid

Peso molecolare: 776.87

Ref: TM-T0864

O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-L-TYROSINE

CAS: 51-48-9

Formula: C₁₅H₁₁I₄NO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 776.8700

Ref: IN-DA0038OW

L-Thyroxine (Liothyronine EP Impurity A, Levothyroxine, Tetraiodothyronine)

CAS: 51-48-9

Formula: C₁₅H₁₁I₄NO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 776.87

Ref: 4Z-T-421

L-Thyroxine

CAS: 51-48-9

Formula: C₁₅H₁₁I₄NO₄

Purezza: ≥ 98.0% (dried basis)

Colore e forma: White to off-white crystalline powder

Peso molecolare: 776.87

Ref: 7W-GP9966

L-Thyroxine

Prodotto controllato

CAS: 51-48-9

Formula: C₁₅H₁₁I₄NO₄

Colore e forma: Neat

Peso molecolare: 776.87

Ref: 04-C17575300

L-Thyroxine (Standard)

CAS: 51-48-9

L-Thyroxine (Standard) is the standard substance of L-Thyroxine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Formula: C₁₅H₁₁I₄NO₄

Colore e forma: Solid

Peso molecolare: 776.87

Ref: TM-TMSM-1492

Levothyroxine

CAS: 51-48-9

Formula: C₁₅H₁₁I₄NO₄

Peso molecolare: 776.87

Ref: ST-EA-CP-L18000

Levothyroxine Lactose Adduct >85%

Prodotto controllato

CAS: 51-48-9

Formula: C₂₇H₃₁I₄NO₁₄

Purezza: >85%

Colore e forma: Neat

Peso molecolare: 1101.151

Ref: TR-L378053

Thyroxine

Prodotto controllato

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Formula: C₁₅H₁₁I₄NO₄

Colore e forma: Neat

Peso molecolare: 776.87

Ref: TR-T425600

Thyroxine (100% pure T4 reference standard (free of T3))

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Formula: C₁₅H₁₁I₄NO₄

Colore e forma: Neat

Peso molecolare: 776.87

Ref: TR-T425650

Liothyronine EP Impurity A

CAS: 51-48-9

Formula: C₁₅H₁₁I₄NO₄

Peso molecolare: 776.9

Ref: ST-EA-CP-L45001

L-Thyroxine-[13C6] Hydrochloride(T4)

CAS: 51-48-9

Ref: BE-MC-2535C6

L-Thyroxine-[13C6] Hydrochloride(T4) in Methanol

CAS: 51-48-9

Methanol

Ref: BE-MC-2535C6XM-100

O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-L-TYROSINE

CAS: 51-48-9

Purezza: 97%

Peso molecolare: 776.8740234

Ref: 10-F837420

2-(3-(4-Hydroxy-3,5-diiodophenoxy)-2,4-diiodobenzamido)-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-Bridged

Prodotto controllato

CAS: 51-48-9

Formula: C₂₈H₁₆I₇NO₇

Colore e forma: Neat

Peso molecolare: 1366.76

Ref: TR-H972213