CAS 52214-84-3

Ciprofibrato

Descrizione:

Ciprofibrato è un composto sintetico classificato come fibrato, utilizzato principalmente nella gestione della dislipidemia, in particolare per abbassare i livelli di trigliceridi e aumentare il colesterolo HDL (lipoproteine ad alta densità). La sua struttura chimica presenta un gruppo fenossilico e un gruppo acido carbossilico, che contribuiscono alle sue proprietà modulatrici dei lipidi. La sostanza è nota per la sua capacità di attivare i recettori attivati da proliferatori di perossisomi (PPAR), che svolgono un ruolo cruciale nel metabolismo dei lipidi. Ciprofibrato è tipicamente somministrato per via orale ed è ben assorbito nel tratto gastrointestinale. Presenta una emivita moderata, consentendo una somministrazione una o due volte al giorno. Il composto è generalmente ben tollerato, sebbene gli effetti collaterali potenziali possano includere disturbi gastrointestinali e problemi muscolari. Come con altri fibrati, è importante monitorare la funzione epatica e i livelli di enzimi muscolari durante il trattamento. Ciprofibrato è spesso utilizzato in combinazione con modifiche dello stile di vita e altri agenti riduttori dei lipidi per ottenere risultati terapeutici ottimali in pazienti con livelli elevati di lipidi.

Formula: C₁₃H₁₄Cl₂O₃

InChI: InChI=1/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

InChI key: InChIKey=KPSRODZRAIWAKH-UHFFFAOYSA-N

SMILES: ClC1(Cl)C(C1)C2=CC=C(OC(C(O)=O)(C)C)C=C2

Sinonimi:

• 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)2-methylpropanoic acid
• 2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acid
• 2-[4-(2,2-Dichloro-cyclopropyl)-phenoxy]-2-methyl-propionic acid
• Brn 1984981
• Ccris 173
• Ciprofibrato
• Ciprofibrato [INN-Spanish]
• Ciprofibratum
• Ciprofibratum [INN-Latin]
• Ciprol
• Lipanor
• Modalim
• Propanoic acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-
• Unii-F8252Jgo9S
• Win 35833
• Ciprofibrate
• 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionicacid
• Cipml
• 2-[4-(2，2-Dichlom-cyclopropyl)phenoxy]-2-methy|propanoic acid
• 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propionicaci
• Ciprofibric acid
• 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propanoicaci
• 2-[P-(2,2-DICHLOROCYCLOPROPYL)-PHENOXY]-2-METHYLPROPANOIC ACID

Ciprofibrate

CAS: 52214-84-3

Formula: C₁₃H₁₄Cl₂O₃

Purezza: >98.0%(GC)(T)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 289.15

Ref: 3B-C2667

Ciprofibrate impurity standard

CAS: 52214-84-3

Ciprofibrate impurity standard

Colore e forma: White

Ref: 47-1312

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate

Formula: C₁₃H₁₄Cl₂O₃

Purezza: 99.9%

Colore e forma: White

Peso molecolare: 288.032

Ref: 47-1278

CIPROFIBRATE CRS

CAS: 52214-84-3

CIPROFIBRATE CRS

Formula: C₁₃H₁₄Cl₂O₃

Colore e forma: Crystalline Powder. White. Whitish. Powder.

Peso molecolare: 289.1545

Ref: 41-Y0000362

Propanoic acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-

CAS: 52214-84-3

Formula: C₁₃H₁₄Cl₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 289.1545

Ref: IN-DA00I9CC

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate

Formula: C₁₃H₁₄Cl₂O₃

Purezza: ≥98%

Peso molecolare: 289.15

Ref: 54-BUP16708

2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid

CAS: 52214-84-3

2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid

Formula: C₁₃H₁₄Cl₂O₃

Purezza: 98%

Peso molecolare: 289.15

Ref: 54-OR1009741

Ciprofibrate

CAS: 52214-84-3

Formula: C₁₃H₁₄Cl₂O₃

Purezza: ≥ 98.0%

Colore e forma: White to light-yellow powder or crystals

Peso molecolare: 289.15

Ref: 7W-GP0375

Ciprofibrate

CAS: 52214-84-3

Formula: C₁₃H₁₄Cl₂O₃

Colore e forma: Off-White Solid

Peso molecolare: 289.15

Ref: 4Z-C-681

Ciprofibrate

CAS: 52214-84-3

Colore e forma: Neat

Ref: 61-FOR1141.00

Ciprofibrate

Prodotto controllato

CAS: 52214-84-3

Formula: C₁₃H₁₄Cl₂O₃

Colore e forma: Neat

Peso molecolare: 289.15

Ref: 86-MM1141.00

Ciprofibrate

CAS: 52214-84-3

2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid

Formula: C₁₃H₁₄Cl₂O₃

Purezza: 98%

Peso molecolare: 289.15

Ref: IN-DG121411

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.

Formula: C₁₃H₁₄Cl₂O₃

Purezza: 99.63% - >99.99%

Colore e forma: White Or Almost White Crystalline Powder

Peso molecolare: 289.15

Ref: TM-T1264

Ciprofibrate

Prodotto controllato

CAS: 52214-84-3

Applications Ciprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.
References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),

Formula: C₁₃H₁₄Cl₂O₃

Colore e forma: Neat

Peso molecolare: 289.15

Ref: TR-C482475

Ciprofibrate - Bio-X ™

CAS: 52214-84-3

Ciprofibrate is a fibrate drug that is used as a lipid-lowering agent. This drug reduces both LDL and VLDL cholesterol levels in the blood. Ciprofibrate works by reducing the production of triglycerides in the liver and increasing the removal of triglycerides from the blood. This drug is an agonist of peroxisome proliferator-activated receptor alpha.

Formula: C₁₃H₁₄Cl₂O₃

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 289.15 g/mol

Ref: 3D-BD164311

2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

CAS: 52214-84-3

2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid (CGP) is a drug that blocks the nuclear receptor PPARγ. It has been shown to reduce cholesterol levels by inhibiting the synthesis of cholesterol, as well as reducing liver lesions in vivo. CGP also inhibits the growth of cancer cells through its ability to bind to DNA and regulate transcriptional activity. The response element for this compound is found in the promoter region of the gene encoding the growth factor-β1 (GF-β1), which is an important regulator of cell proliferation, differentiation, and apoptosis. CGP also inhibits peroxisome proliferator activator receptor α (PPARα) and γ (PPARγ). This inhibition leads to decreased expression of genes involved in lipid metabolism, such as acyl CoA synthase and fatty acid synthetase. CGP has also been shown to be carcinogenic in vivo

Formula: C₁₃H₁₄Cl₂O₃

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 289.15 g/mol

Ref: 3D-FD11320

2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid

CAS: 52214-84-3

Formula: C₁₃H₁₄Cl₂O₃

Purezza: 95.0%

Colore e forma: Solid, White to slightly pale yellow powder

Peso molecolare: 289.15

Ref: 10-F212903

Ciprofibrate

CAS: 52214-84-3

Formula: C₁₃H₁₄Cl₂O₃

Peso molecolare: 289.15

Ref: ST-EA-CP-C77000