CAS 524-17-4

Dauricina

Descrizione:

Dauricina, con il numero CAS 524-17-4, è un alcaloide derivato da varie specie vegetali, in particolare quelle della famiglia Menispermaceae. È noto per la sua complessità strutturale, caratterizzata da un framework tetraciclico che contribuisce alla sua attività biologica. Dauricina presenta una gamma di proprietà farmacologiche, inclusi effetti analgesici, anti-infiammatori e potenziali effetti antitumorali, rendendolo di interesse nella chimica medicinale. Il composto si trova tipicamente sotto forma di solido cristallino bianco a giallo pallido ed è solubile in solventi organici come etanolo e cloroformio, ma meno solubile in acqua. Si pensa che il suo meccanismo d'azione coinvolga la modulazione dei sistemi di neurotrasmettitori e l'interferenza con le vie di segnalazione cellulare. A causa della sua natura bioattiva, la ricerca continua sul suo potenziale terapeutico e sul profilo di sicurezza, sebbene siano necessari ulteriori studi per comprendere appieno la sua efficacia e i meccanismi in vari contesti biologici. Come con molti alcaloidi, si consiglia cautela riguardo al suo uso, poiché potrebbe presentare tossicità a concentrazioni più elevate.

Formula: C₃₈H₄₄N₂O₆

InChI: InChI=1/C38H44N2O6/c1-39-15-13-26-20-35(42-3)37(44-5)22-29(26)31(39)17-24-7-10-28(11-8-24)46-34-19-25(9-12-33(34)41)18-32-30-23-38(45-6)36(43-4)21-27(30)14-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3

InChI key: InChIKey=AQASRZOCERRGBL-ROJLCIKYSA-N

SMILES: C([C@@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC(OC4=CC=C(C[C@@H]5C=6C(=CC(OC)=C(OC)C6)CCN5C)C=C4)=C(O)C=C3

Sinonimi:

• 4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]-2-{4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]Phenoxy}Phenol
• 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenol
• 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-(4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenoxy)phenol
• Nsc 36413
• Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-, (R-(R*,R*))-
• Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-
• Dauricine
• 6,6'-Di-O-Methyldauricoline
• Menispermum dauricum DC Extract
• (r-(r*,r*))-y)
• -(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenox
• dauricine (8ci)

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Peso molecolare: 624.77

Ref: 7W-GP0181

Dauricine

CAS: 524-17-4

Dauricine

Formula: C₃₈H₄₄N₂O₆

Purezza: 99.5%

Peso molecolare: 624.77

Ref: 54-BUP07831

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 624.7658

Ref: IN-DA00DEJ0

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Purezza: 95%~99%

Peso molecolare: 624.778

Ref: BP-BP0452

Dauricine (Standard)

CAS: 524-17-4

Dauricine (Standard) is a reference standard for research and analysis in studies involving Dauricine. 1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes.

Formula: C₃₈H₄₄N₂O₆

Peso molecolare: 624.7658

Ref: TM-TMSM-0845

Dauricine

Prodotto controllato

CAS: 524-17-4

Applications Dauricine is a bisbenzylisoquinoline allkaloid derivative that displays a noted number of pharmaceutical properties. It is known to induces severe lung toxicity in animals.
References Xie, H. et al.: Anal. Bioanal. Chem., 408, 4111 (2016);

Formula: C₃₈H₄₄N₂O₆

Colore e forma: Neat

Peso molecolare: 624.77

Ref: TR-D194825

Dauricine

CAS: 524-17-4

1.

Formula: C₃₈H₄₄N₂O₆

Purezza: 99.24% - 99.75%

Colore e forma: Solid

Peso molecolare: 624.7658

Ref: TM-T6S0119

Dauricine

CAS: 524-17-4

Natural alkaloid

Formula: C₃₈H₄₄N₂O₆

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 624.78

Ref: 5G-80419

Dauricine

CAS: 524-17-4

Dauricine is a natural bisbenzylisoquinoline alkaloid, which is derived from the plant Menispermum dauricum, commonly found in regions of Asia. Its mode of action involves inhibition of various ion channels, notably the calcium and potassium channels, as well as modulation of signaling pathways that influence cell proliferation and apoptosis. These biochemical activities endow Dauricine with the potential to influence cardiovascular, neurological, and oncological outcomes.

Formula: C₃₈H₄₄N₂O₆

Purezza: Min. 95%

Colore e forma: Brown Yellow Powder

Peso molecolare: 624.77 g/mol

Ref: 3D-FD66056

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Peso molecolare: 624.8

Ref: BE-RMT10620

Dauricine

CAS: 524-17-4

4-(((R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-2-(4-(((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)phenoxy)phenol

Formula: C₃₈H₄₄N₂O₆

Purezza: 98%

Peso molecolare: 624.77

Ref: IN-DG123496

DAURICINE

CAS: 524-17-4

Purezza: 98%

Peso molecolare: 624.7780151

Ref: 10-F794658