CAS 54024-22-5

Desogestrel

Descrizione:

Desogestrel è un progestinico sintetico, utilizzato principalmente nei contraccettivi ormonali. È caratterizzato dalla sua capacità di imitare l'ormone naturale progesterone, regolando così l'ovulazione e i cicli mestruali. Desogestrel è noto per la sua alta biodisponibilità orale ed è spesso combinato con estrogeni in pillole anticoncezionali orali combinate. La sua struttura chimica presenta un anello ciclopropano, che contribuisce alla sua stabilità ed efficacia. La sostanza è lipofila, permettendo una buona assorbimento nel tratto gastrointestinale. Desogestrel ha una vita media relativamente lunga, che supporta il suo utilizzo in regimi contraccettivi giornalieri. Inoltre, presenta un'attività androgenica minima, rendendolo una scelta preferita per le persone che possono sperimentare effetti collaterali da progestinici più androgenici. Il profilo farmacologico di Desogestrel include effetti sull'endometrio, sul muco cervicale e sulla soppressione dell'ovulazione, rendendolo efficace nella prevenzione della gravidanza. Come per qualsiasi farmaco, è necessario considerare i potenziali effetti collaterali e controindicazioni, ed è essenziale consultare professionisti sanitari per un consiglio personalizzato.

Formula: C₂₂H₃₀O

InChI: InChI=1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

InChI key: InChIKey=RPLCPCMSCLEKRS-BPIQYHPVSA-N

SMILES: C(C)[C@@]12[C@]([C@]3([C@](C(=C)C1)([C@@]4(C(CC3)=CCCC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]

Sinonimi:

• (+)-13β-Ethyl-17α-ethynyl-11-methylenegon-4-en-17β-ol
• (17a)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
• (17alpha)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
• (8S,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-11-methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)
• (8S,9S,10R,13S,14S,17R)-17-Ethinyl-13-ethyl-11-methyliden-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol
• 13-Ethyl-11-methylene-18,19-dinor-17α-4-pregnen-20-yn-17-ol
• 17-Ethynyl-18-methyl-11-methyleneestr-4-en-17β-ol
• 17a-Ethynyl-18-methyl-11-methyl-ene-D4-estren-17b-ol
• 18,19-Dinorpregn-4-en-20-yn-17-ol, 13-ethyl-11-methylene-, (17α)-
• 258-929-4
• Cerazette
• Cyclosa
• Dicromil
• Marvelon 150/320
• Org 2969
• DESOGESTREL
• org2969
• 18,19-Dinorpregn-4-en-20-yn-17-ol, 13-ethyl-11-methylene-, (17.alpha.)-
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-Methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol
• (17R)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
• 13-ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol
• DESOGESTRAL
• (17β)-13-Ethyl-11-methylene-19-nor-pregn-4-en-20-yn-17-ol
• Desogestrel for system suitability, European Pharmacopoeia (EP) Reference Standard
• 13-ethyl-11-methylene-19-dinorpregn-4-en-20-yn-17-o(17-alpha)-1
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol
• DESTODENE
• Desogestrel (50 mg)

Desogestrel

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 310.48

Ref: 3B-D4163

Desogestrel

CAS: 54024-22-5

Desogestrel

Formula: C₂₂H₃₀O

Purezza: 99.8%

Colore e forma: White To Off-White

Peso molecolare: 310.22967

Ref: 47-568

DESOGESTREL CRS

CAS: 54024-22-5

DESOGESTREL CRS

Formula: C₂₂H₃₀O

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 310.473

Ref: 41-Y0000509

DESOGESTREL FOR SYSTEM SUITABILITY CRS

CAS: 54024-22-5

DESOGESTREL FOR SYSTEM SUITABILITY CRS

Formula: C₂₂H₃₀O

Peso molecolare: 310.473

Ref: 41-Y0000510

Desogestrel

CAS: 54024-22-5

Estrogens and progestins

Formula: C₂₂H₃₀O

Colore e forma: White Crystalline Powder

Peso molecolare: 310.22967

Ref: 45-1173235

Desogestrel

CAS: 54024-22-5

Desogestrel

Formula: C₂₂H₃₀O

Purezza: 99.5%

Colore e forma: Solid

Peso molecolare: 310.47

Ref: 54-BUP11759

Desogestrel

CAS: 54024-22-5

Desogestrel

Formula: C₂₂H₃₀O

Purezza: >98%

Peso molecolare: 310.48

Ref: 54-OR1025609

Desogestrel

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Colore e forma: White To Off-White Solid

Peso molecolare: 310.48

Ref: 4Z-D-167

Desogestrel

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Colore e forma: White To Off-White

Peso molecolare: 310.47

Ref: 61-FOR1024.00

Desogestrel

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Colore e forma: Neat

Peso molecolare: 310.47

Ref: 86-MM1024.00

Desogestrel

Prodotto controllato

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Colore e forma: Neat

Peso molecolare: 310.47

Ref: 04-C12170120

13-ethyl-17-ethynyl-11-methylene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol;(17α)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-o

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 310.4730

Ref: IN-DA003P9R

Desogestrel-13C2,d2 (Major)

Prodotto controllato

CAS: 54024-22-5

Applications A labelled progestogen with low androgenic potency.
References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)

Formula: C₂₀₁₃C₂H₂₈D₂O

Colore e forma: Neat

Peso molecolare: 314.47

Ref: TR-D296877

Desogestrel

Prodotto controllato

CAS: 54024-22-5

Applications A progestogen with low androgenic potency.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)

Formula: C₂₂H₃₀O

Colore e forma: Neat

Peso molecolare: 310.47

Ref: TR-D296875

Desogestrel

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to almost white powder

Peso molecolare: 310.47

Ref: 7W-GP5321

Desogestrel

CAS: 54024-22-5

Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

Formula: C₂₂H₃₀O

Purezza: 99.8% - 99.95%

Colore e forma: Crystals Solid

Peso molecolare: 310.473

Ref: TM-T6819

Desogestrel

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Colore e forma: Solid

Peso molecolare: 310.5

Ref: BE-RMCD073000

Desogestrel

CAS: 54024-22-5

Formula: C₂₂H₃₀O

Peso molecolare: 310.5

Ref: ST-EA-CP-D35000

Desogestrel

Prodotto controllato

CAS: 54024-22-5

Desogestrel is a progestin that is often used in combination with ethinyl estradiol in oral contraceptives. It has been shown to reduce ovarian activity and has a high level of resistance to metabolism by cytochrome P450 enzymes. Desogestrel has been widely used for the treatment of inflammatory lesions, such as those found on the skin or in the mouth, but it does not have any therapeutic effects against inflammation in other parts of the body. Desogestrel is an active metabolite of nomegestrol acetate, which has been shown to have anti-inflammatory properties. The effect of desogestrel on inflammatory lesions may be due to its ability to inhibit prostaglandin synthesis and its anti-inflammatory effects.

Formula: C₂₂H₃₀O

Purezza: Min. 98 Area-%

Peso molecolare: 310.47 g/mol

Ref: 3D-FD21372