CAS 55481-88-4

Mollugin

Descrizione:

Mollugin è un composto che si trova naturalmente, derivato principalmente dalla specie vegetale *Mollugo nudicaulis*, appartenente alla famiglia Molluginaceae. È caratterizzato dalla sua complessa struttura chimica, che include più gruppi funzionali che contribuiscono alla sua attività biologica. Mollugin ha suscitato interesse nel campo della chimica medicinale grazie alle sue potenziali proprietà farmacologiche, tra cui attività anti-infiammatorie, antiossidanti e anticancro. Il composto mostra una gamma di effetti biologici, che possono essere attribuiti alla sua capacità di modulare vari percorsi cellulari. Inoltre, la solubilità e stabilità di Mollugin in diversi solventi possono variare, influenzando la sua biodisponibilità e efficacia nelle applicazioni terapeutiche. La ricerca su Mollugin è in corso, con studi focalizzati sui suoi meccanismi d'azione, potenziali usi terapeutici e la sintesi di analoghi per migliorare le sue proprietà. Come molti prodotti naturali, l'esplorazione delle caratteristiche di Mollugin continua a rivelare la sua importanza sia nella medicina tradizionale che nella farmacologia moderna.

Formula: C₁₇H₁₆O₄

InChI: InChI=1/C17H16O4/c1-17(2)9-8-12-13(16(19)20-3)14(18)10-6-4-5-7-11(10)15(12)21-17/h4-9,18H,1-3H3

InChI key: InChIKey=VLGATXOTCNBWIT-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C2C(=C3C(=C1O)C=CC=C3)OC(C)(C)C=C2

Sinonimi:

• 2H-naphtho[1,2-b]pyran-5-carboxylic acid, 6-hydroxy-2,2-dimethyl-, methyl ester
• Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
• Rubimaillin
• Smb 00431
• Mollugin
• 2H-Naphtho[1,2-b]pyran-5-carboxylic acid
• Mollugin/rubiMaillin
• 6-Hydroxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
• Mollugin, 98%, from Rubia cordifolia L.
• 6-hydroxy-2, 2-dimethyl-, methylester
• RUBIMAILLIN; MOLLUGIN
• 2-DiMethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid Methyl ester
• 6-Hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylic Acid Methyl Ester
• 2,2-Dimethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
• MOLLUGIN(SH)

Mollugin

CAS: 55481-88-4

Formula: C₁₇H₁₆O₄

Purezza: >98.0%(HPLC)

Colore e forma: White to Yellow to Orange powder to crystal

Peso molecolare: 284.31

Ref: 3B-M3091

Methyl 6-Hydroxy-2,2-Dimethyl-2H-Benzo[H]Chromene-5-Carboxylate

CAS: 55481-88-4

Methyl 6-Hydroxy-2,2-Dimethyl-2H-Benzo[H]Chromene-5-Carboxylate

Formula: C₁₇H₁₆O₄

Purezza: 99%

Peso molecolare: 284.31

Ref: 54-OR1013849

Mollugin

CAS: 55481-88-4

Formula: C₁₇H₁₆O₄

Peso molecolare: 284.31

Ref: 7W-GY1430

Mollugin

CAS: 55481-88-4

Mollugin

Formula: C₁₇H₁₆O₄

Purezza: ≥95%

Peso molecolare: 284.31

Ref: 54-BUP10672

Mollugin

CAS: 55481-88-4

Mollugin is a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Mollugin has anticancer efficacy, can modulate the HER2, HO-1, Nrf2 , and NF- κB pathways.

Formula: C₁₇H₁₆O₄

Purezza: 95%~99%

Peso molecolare: 284.311

Ref: BP-BP1228

Mollugin (Standard)

CAS: 55481-88-4

Mollugin (Standard) is the standard for Mollugin. Mollugin selectively inhibits the NLRP3 inflammasome, coordinately regulates inflammation and oxidative stress to promote regeneration, and induces ferroptosis in NSCLC while inhibiting tumor growth in vivo.

Formula: C₁₇H₁₆O₄

Peso molecolare: 284.31

Ref: TM-TMSM-1228

Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate

CAS: 55481-88-4

Formula: C₁₇H₁₆O₄

Purezza: %

Colore e forma: Solid

Peso molecolare: 284.3065

Ref: IN-DA00DE0G

Mollugin

CAS: 55481-88-4

Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.

Formula: C₁₇H₁₆O₄

Purezza: 99.87% - ≥95%

Colore e forma: Solid

Peso molecolare: 284.31

Ref: TM-T3673

Mollugin

CAS: 55481-88-4

Oxygen-heterocyclic compound

Formula: C₁₇H₁₆O₄

Purezza: ≥ 95.0 % (HPLC)

Peso molecolare: 284.31

Ref: 5G-80499

Mollugin

CAS: 55481-88-4

Formula: C₁₇H₁₆O₄

Peso molecolare: 284.31

Ref: BE-RMT11130

Mollugin

CAS: 55481-88-4

Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate

Formula: C₁₇H₁₆O₄

Purezza: 98+%

Peso molecolare: 284.31

Ref: IN-DG140248

Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate

CAS: 55481-88-4

Purezza: ≥98%(HPLC)

Peso molecolare: 284.3110046

Ref: 10-F868957

Mollugin

Prodotto controllato

CAS: 55481-88-4

Applications Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.
References Zhang, L. et al.: Biochem. Biophys. Res. Comm., 450, 247 (2014); Idhayadhulla, A. et al.: Bioorg. Chem., 52, 77 (2014);

Formula: C₁₇H₁₆O₄

Colore e forma: Neat

Peso molecolare: 284.31

Ref: TR-M487600

Mollugin

CAS: 55481-88-4

Mollugin is a bioactive compound, which is derived from the plant Rubia cordifolia. As a phytochemical, it is part of the anthraquinone family, isolated through extraction processes from the root of its source plant. Its mode of action involves modulating various biochemical pathways, notably exhibiting anti-inflammatory, anticancer, and antioxidant activities. These effects are primarily mediated through the inhibition of specific enzymes and signaling pathways, including the NF-κB and MAPK pathways, which are central to inflammatory and cancer processes.

Purezza: Min. 95%

Ref: 3D-FM145252