CAS 56-75-7

(-)-Cloramfenicolo

Descrizione:

(-)-Cloramfenicolo, con il numero CAS 56-75-7, è un antibiotico ad ampio spettro originariamente derivato dal batterio Streptomyces venezuelae. È caratterizzato dalla sua capacità di inibire la sintesi proteica batterica legandosi alla subunità 50S del ribosoma batterico, bloccando efficacemente la formazione di legami peptidici. Questo composto è una polvere cristallina bianca o bianco sporco che è solubile in acqua e alcol, ma ha una solubilità limitata nei solventi organici. La sua formula molecolare è C11H12Cl2N2O5 e ha un peso molecolare di circa 323,13 g/mol. (-)-Cloramfenicolo mostra attività antibatterica contro un'ampia gamma di batteri Gram-positivi e Gram-negativi, rendendolo utile nel trattamento di varie infezioni. Tuttavia, il suo uso è limitato a causa di potenziali effetti collaterali, tra cui anemia aplastica e sindrome del bambino grigio nei neonati. Di conseguenza, è spesso riservato per infezioni gravi in cui altri antibiotici sono inefficaci. Una corretta gestione e dosaggio sono cruciali per minimizzare gli effetti avversi e garantire l'efficacia terapeutica.

Formula:C₁₁H₁₂Cl₂N₂O₅

InChI:InChI=1/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9?/m1/s1

InChI key:InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N

SMILES:[C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(N(=O)=O)C=C1

Sinonimi:

2,2-Dichloro-N-(2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl)-Acetamid
2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
2,2-Dichloro-N-[2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide
2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
2,2-dichloro-N-[(1R,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
2,2-dichloro-N-[(1S,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
Ak-Chlor
Alficetyn
Amphenicol
Amphicol
Amseclor
Anacetin
Aquamycetin
Austracol
Bradyoxetin
CAF
CAM
CAP
CPh
Catilan
Chemicetin
Chemicetina
Chlomycol
Chloramex
Chloramphenicol
Chloramsaar
Chlorasol
Chlorcetin
Chloricol
Chlorocaps
Chlorocid
Chlorocide
Chlorocin
Chloromycetin
Chloronitrin
Chloroptic
Ciplamycetin
Cloramfen
Cloramfenicol
Cloramficin
Cloramicol
Clorocyn
Cloromisan
Cylphenicol
D-(-)-Chloramphenicol
D-(-)-Threo-2,2-Dichloro-N-[Beta-Hydroxy-Alpha-(Hydroxy-Methyl)-P-Nitrophenethyl]Acetamide
D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol
D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol
D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol
D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
D-(-)-threo-Chloramphenicol
D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
Detreomycin
Embacetin
Enicol
Enteromycetin
Farmicetina
Fenicol
Globenicol
Gloveticol
Halcetin
Intramycetin
Ismicetina
Juvamycetin
Kamaver
Kemicetine
Klorita
Leukomyan
Leukomycin
Levocin
Levomicetina
Levomitsetin
Levomycetin
Levoplast
Levosin
Levovetin
Loromisin
Mastiphen
Micloretin
Micoclorina
Microcetina
Mychel
Mychel-Vet
Mycinol
Myclocin
Mycochlorin
Novomycetin
Ocuphenicol
Opclor
Ophthochlor
Pantovernil
Paraxin
Quemicetina
Ronphenil
Septicol
Sintomicetin
Sintomicetina
Soluthor
Stanomycetin
Synthomycetin
Synthomycin
Tevcocin
Tifomycine
Treomicetina
Unimycetin
Veticol
Viceton
[R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
D,L-chloramphenicol
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
nitrophenyl)ethyl]acetamide
Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-
D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENETHYL]ACETAMIDE
D-THREO-(-)-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-HYDROXYMETHYL-P-NITROPHENETHYL]ACETAMIDE
D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENYL] ACETAMIDE
D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
D-2-DICHLOROACETAMIDO-1-P-NITRO-PHENYL-1,3-PROPANEDIOL
[R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide
D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE
D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE
D-(-)-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
CHLORAMPHENICOLUM
D-(-)-THREO-2-DICHLOROACETAMIDO-1-[P-NITRO-PHENYL]-1,3-PROPANEDIOL
,[theta-(theta,theta)]-
D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE
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