CAS 58-28-6

Cloridrato di desipramina

Descrizione:

Cloridrato di desipramina è un antidepressivo triciclico utilizzato principalmente nel trattamento del disturbo depressivo maggiore e di alcuni disturbi d'ansia. Funziona inibendo il riassorbimento della norepinefrina e, in misura minore, della serotonina, aumentando così i livelli di questi neurotrasmettitori nella fessura sinaptica. Questo meccanismo contribuisce ai suoi effetti antidepressivi. La sostanza appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, rendendola adatta per somministrazione orale in forma di compresse o come soluzione iniettabile. Cloridrato di desipramina ha una emivita relativamente lunga, consentendo una somministrazione una volta al giorno in molti casi. Gli effetti collaterali comuni possono includere secchezza delle fauci, stitichezza, ritenzione urinaria e sedazione, mentre i rischi più gravi coinvolgono problemi cardiovascolari e potenziale di sovradosaggio. A causa del suo profilo di effetti collaterali, di solito viene prescritto con cautela, in particolare nei pazienti con condizioni cardiache preesistenti. Come con tutti i farmaci, è essenziale che i pazienti consultino professionisti sanitari per consigli personalizzati e monitoraggio durante il trattamento.

Formula: C₁₈H₂₃ClN₂

InChI: InChI=1/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H

InChI key: InChIKey=XAEWZDYWZHIUCT-UHFFFAOYSA-N

SMILES: C(CCNC)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Sinonimi:

• 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine hydrochloride
• 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride
• 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride (1:1)
• 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine hydrochloride
• 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride
• 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, monohydrochloride
• 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-, hydrochloride (1:1)
• DMI hydrochloride
• Demethylimipramine hydrochloride
• Desimipramine, hydrochloride
• Desipramine HCl
• Desipramine hydrochloride [USAN:JAN]
• Desipramine monohydrochloride
• Desmethylimipramine chloride
• Desmethylimipramine hydrochloride
• Desmethylimipramine monohydrochloride
• Despramine Hydrochloride
• Ex 4355
• G 35020
• GMI
• Imipraminedemethyl hydrochloride
• Jb 8181
• N-(gamma-Methylaminopropyl)iminodibenzyl hydrochloride
• N-(γ-Methylaminopropyl)iminodibenzyl hydrochloride
• Norpolake
• Norpramin
• Nortimil
• Nortrimil
• Nsc 114901
• Pertofran
• Pertofrane
• Pertofrin
• Petilil
• Petylyl
• Rmi 9,384A
• Unii-1Y58Do4My1
• Desipramine hydrochloride
• n-(gamma-methylaminopropyl)iminodibenzylhydrochloride
• demethylimipraminehydrochloride
• Desipramine solution hydrochloride
• f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(monohydrochlor
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine
• Desipramine Hydrochloride (125 mg)I0E2831.000mg/mg(dr)
• Desipramine hydrochloride solution
• desmethylimipraminehydrochloride
• dmihydrochloride
• 5H-Dibenzb,fazepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
• imipraminedemethylhydrochloride
• g35020
• ex4355
• 10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(b,f)azepinehydrochloride
• 3-(5,6-dihydrobenzo[b][1
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methyl-amine
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine hydrochloride
• 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine hydrochloride
• jb8181
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
• Desipramine Hydrochloride (125 mg)
• [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine hydrochloride
• 10,11-DIHYDRO-N-METHYL-5-H-DIBENZ-[B,F]AZEPINE HYDROCHLORIDE
• f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(hydrochlorid
• DESIPRAMINEHYDROCHLORIDE,USP
• DESIPRAMINE HYDROCHLORIDE METHANOL*SOLUT ION

Desipramine.HCl

CAS: 58-28-6

Colore e forma: Neat

Ref: LP-DSP-1093-HC-10

Desipramine.HCl, 1mg/ml in Methanol (as free base)

CAS: 58-28-6

Colore e forma: Single Solution

Ref: LP-DSP-1093-HC-1LM

Desipramine Hydrochloride

CAS: 58-28-6

Colore e forma: Neat

Ref: 61-FOR0589.00

Desipramine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 58-28-6

Colore e forma: Single Solution

Ref: 61-AMP0589.00-01

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride

Formula: C₁₈H₂₃ClN₂

Colore e forma: Off-White

Peso molecolare: 302.8416

Ref: 47-931

DESIPRAMINE HYDROCHLORIDE CRS

CAS: 58-28-6

DESIPRAMINE HYDROCHLORIDE CRS

Formula: C₁₈H₂₃ClN₂

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 302.8416

Ref: 41-D0500000

Desipramine Hydrochloride

CAS: 58-28-6

Antidepressants, tranquilizers and other psychotherapeutic agents, nesoi

Formula: C₁₈H₂₂N₂·HCl

Colore e forma: White Off-White Powder

Peso molecolare: 302.15498

Ref: 45-1172006

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.

Formula: C₁₈H₂₃ClN₂

Purezza: 99.58% - 99.94%

Colore e forma: White To Off-White Powder

Peso molecolare: 302.842

Ref: TM-T0991

Desipramine HCl

CAS: 58-28-6

Formula: C₁₈H₂₂N₂·HCl

Peso molecolare: 266.39 36.46

Ref: 4Z-D-026

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride

Purezza: ≥98%

Peso molecolare: 302.842g/mol

Ref: 54-BUP14958

Desipramine Hydrochloride

CAS: 58-28-6

Desipramine Hydrochloride

Purezza: 98%

Peso molecolare: 302.84g/mol

Ref: 54-OR1027543

Desipramine hydrochloride

CAS: 58-28-6

Formula: C₁₈H₂₂N₂·HCl

Purezza: ≥ 97.0%

Colore e forma: White to off-white powder

Peso molecolare: 302.84

Ref: 7W-GP4485

Desipramine Hydrochloride

Prodotto controllato

CAS: 58-28-6

Formula: C₁₈H₂₂N₂·ClH

Colore e forma: Neat

Peso molecolare: 302.84

Ref: 86-MM0589.00

Desipramine hydrochloride

CAS: 58-28-6

Formula: C₁₈H₂₂N₂·ClH

Colore e forma: Neat

Peso molecolare: 302.84

Ref: 04-C12170167

Desipramine Hydrochloride

CAS: 58-28-6

Formula: C₁₈H₂₂N₂·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 302.85

Ref: 3B-D6181

Desipramine Hydrochloride

Prodotto controllato

CAS: 58-28-6

Applications Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),

Formula: C₁₈H₂₂N₂·ClH

Colore e forma: Off-White

Peso molecolare: 302.84

Ref: TR-D290050

Desipramine HCl

Prodotto controllato

CAS: 58-28-6

Desipramine hydrochloride is a tricyclic antidepressant drug that has been used to treat depression. It is an ester of N-methyl-D-aspartate and inhibits the 5-HT2 receptors. Desipramine HCl has been shown to have anti-cancer properties in both animal models and human cell lines, inhibiting carcinoma cells’ growth. The drug also has an effect on locomotor activity in mice and its use may cause drug interactions with nonsteroidal anti-inflammatory drugs.

Formula: C₁₈H₂₃ClN₂

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 302.84 g/mol

Ref: 3D-FD21203