CAS 58-28-6
:Cloridrato di desipramina
Descrizione:
Cloridrato di desipramina è un antidepressivo triciclico utilizzato principalmente nel trattamento del disturbo depressivo maggiore e di alcuni disturbi d'ansia. Funziona inibendo il riassorbimento della norepinefrina e, in misura minore, della serotonina, aumentando così i livelli di questi neurotrasmettitori nella fessura sinaptica. Questo meccanismo contribuisce ai suoi effetti antidepressivi. La sostanza appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, rendendola adatta per somministrazione orale in forma di compresse o come soluzione iniettabile. Cloridrato di desipramina ha una emivita relativamente lunga, consentendo una somministrazione una volta al giorno in molti casi. Gli effetti collaterali comuni possono includere secchezza delle fauci, stitichezza, ritenzione urinaria e sedazione, mentre i rischi più gravi coinvolgono problemi cardiovascolari e potenziale di sovradosaggio. A causa del suo profilo di effetti collaterali, di solito viene prescritto con cautela, in particolare nei pazienti con condizioni cardiache preesistenti. Come con tutti i farmaci, è essenziale che i pazienti consultino professionisti sanitari per consigli personalizzati e monitoraggio durante il trattamento.
Formula:C18H23ClN2
InChI:InChI=1/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H
InChI key:InChIKey=XAEWZDYWZHIUCT-UHFFFAOYSA-N
SMILES:C(CCNC)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Sinonimi:- 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine hydrochloride
- 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride
- 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride (1:1)
- 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine hydrochloride
- 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride
- 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, monohydrochloride
- 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-, hydrochloride (1:1)
- DMI hydrochloride
- Demethylimipramine hydrochloride
- Desimipramine, hydrochloride
- Desipramine HCl
- Desipramine hydrochloride [USAN:JAN]
- Desipramine monohydrochloride
- Desmethylimipramine chloride
- Desmethylimipramine hydrochloride
- Desmethylimipramine monohydrochloride
- Despramine Hydrochloride
- Ex 4355
- G 35020
- GMI
- Imipraminedemethyl hydrochloride
- Jb 8181
- N-(gamma-Methylaminopropyl)iminodibenzyl hydrochloride
- N-(γ-Methylaminopropyl)iminodibenzyl hydrochloride
- Norpolake
- Norpramin
- Nortimil
- Nortrimil
- Nsc 114901
- Pertofran
- Pertofrane
- Pertofrin
- Petilil
- Petylyl
- Rmi 9,384A
- Unii-1Y58Do4My1
- Desipramine hydrochloride
- n-(gamma-methylaminopropyl)iminodibenzylhydrochloride
- demethylimipraminehydrochloride
- Desipramine solution hydrochloride
- f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(monohydrochlor
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine
- Desipramine Hydrochloride (125 mg)I0E2831.000mg/mg(dr)
- Desipramine hydrochloride solution
- desmethylimipraminehydrochloride
- dmihydrochloride
- 5H-Dibenzb,fazepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
- imipraminedemethylhydrochloride
- g35020
- ex4355
- 10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(b,f)azepinehydrochloride
- 3-(5,6-dihydrobenzo[b][1
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methyl-amine
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine hydrochloride
- 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine hydrochloride
- jb8181
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
- Desipramine Hydrochloride (125 mg)
- [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine hydrochloride
- 10,11-DIHYDRO-N-METHYL-5-H-DIBENZ-[B,F]AZEPINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(hydrochlorid
- DESIPRAMINEHYDROCHLORIDE,USP
- DESIPRAMINE HYDROCHLORIDE METHANOL*SOLUT ION
- Vedi altri sinonimi
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Desipramine Hydrochloride
CAS:Formula:C18H22N2·HClPurezza:>98.0%(HPLC)(T)Colore e forma:White to Light yellow powder to crystalPeso molecolare:302.85Desipramine hydrochloride
CAS:Desipramine hydrochlorideFormula:C18H23ClN2Colore e forma:Off-WhitePeso molecolare:302.8416DESIPRAMINE HYDROCHLORIDE CRS
CAS:DESIPRAMINE HYDROCHLORIDE CRSFormula:C18H23ClN2Colore e forma:Added ModifiedPeso molecolare:302.8416Desipramine Hydrochloride
CAS:Antidepressants, tranquilizers and other psychotherapeutic agents, nesoiFormula:C18H22N2·HClColore e forma:White Off-White PowderPeso molecolare:302.15498Desipramine hydrochloride
CAS:Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.Formula:C18H23ClN2Purezza:99.58% - 99.96%Colore e forma:Gray SolidPeso molecolare:302.842Desipramine Hydrochloride
CAS:Desipramine HydrochlorideFormula:C18H23ClN2Purezza:>98%Colore e forma:SolidPeso molecolare:302.84Desipramine hydrochloride
CAS:Formula:C18H22N2·HClPurezza:≥ 97.0%Colore e forma:White to off-white powderPeso molecolare:302.84Desipramine hydrochloride
CAS:Desipramine hydrochlorideFormula:C18H23ClN2Purezza:≥98%Colore e forma:SolidPeso molecolare:302.842Desipramine HCl (N-Desmethyl Imipramine HCl, N-Desmethyl Clomipramine HCl EP Impurity B HCl, Norimipramine HCl)
CAS:Formula:C18H22N2HClPeso molecolare:266.39 36.46Desipramine.HCl, 1mg/ml in Methanol (as free base)
CAS:Formula:C18H22N2·ClHColore e forma:Single SolutionPeso molecolare:302.84Desipramine Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS:Formula:C18H22N2·ClHColore e forma:ColourlessPeso molecolare:302.84Desipramine hydrochloride (Standard)
CAS:Desipramine hydrochloride (Standard) is a reference standard for research and analysis in studies involving Desipramine hydrochloride. Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.Formula:C18H23ClN2Colore e forma:SolidPeso molecolare:302.842Desipramine Hydrochloride
CAS:Prodotto controllatoFormula:C18H22N2·ClHColore e forma:NeatPeso molecolare:302.84Desipramine Hydrochloride
CAS:Prodotto controllatoApplications Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),Formula:C18H22N2·ClHColore e forma:NeatPeso molecolare:302.84
