CAS 58-46-8

(±)-Tetrabenazina

Descrizione:

(±)-Tetrabenazina è un composto chimico utilizzato principalmente come farmaco per il trattamento dei disturbi del movimento, in particolare in condizioni come la malattia di Huntington e la discinesia tardiva. È classificato come un agente depletore di monoamine, mirato specificamente alla deplezione di neurotrasmettitori come la dopamina. Il composto ha una struttura complessa con un nucleo di tetrabenazina, che contribuisce alla sua attività farmacologica. È noto per la sua capacità di ridurre i movimenti involontari modulando l'attività dopaminergica nel cervello. La sostanza è tipicamente somministrata nella sua forma di sale cloridrato ed è caratterizzata dalla sua relativamente bassa solubilità in acqua, che influisce sulla sua biodisponibilità. Gli effetti collaterali possono includere sedazione, depressione e disturbi gastrointestinali, richiedendo un attento monitoraggio durante il trattamento. A causa dei suoi effetti sui livelli di neurotrasmettitori, (±)-Tetrabenazina è classificato come sostanza controllata in alcune giurisdizioni, riflettendo il suo potenziale di abuso e la necessità di un uso regolato in contesti clinici.

Formula: C₁₉H₂₇NO₃

InChI: InChI=1/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/s2

InChI key: InChIKey=MKJIEFSOBYUXJB-VTLFJGNJNA-N

SMILES: O(C)C=1C=C2[C@]3(N(C[C@H](CC(C)C)C(=O)C3)CCC2=CC1OC)[H]

Sinonimi:

• 2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine
• 2H-Benzo[A]Quinolizin-2-One, 1,3,4,6,7,11B-Hexahydro-9,10-Dimethoxy-3-(2-Methylpropyl)-, (3R,11Br)-Rel-
• 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-
• 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis-
• 2H-benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
• 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
• 9,10-Dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isochinolin-2-on
• 9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
• Nsc 169886
• Nsc 172187
• Ro 1-9569
• Rubigen
• Tetrabenazin
• Tetrabenazina
• Xenazine
• cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine

Tetrabenazine

CAS: 58-46-8

Formula: C₁₉H₂₇NO₃

Purezza: >99.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 317.43

Ref: 3B-T2839

Tetrabenazine ((3RS,11bRS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one)

CAS: 58-46-8

Drugs primarily affecting the central nervous system, not elsewhere specified or included

Formula: C₁₉H₂₇NO₃

Colore e forma: White Crystalline Powder

Peso molecolare: 317.19909

Ref: 45-1649801

TETRABENAZINE

CAS: 58-46-8

Formula: C₁₉H₂₇NO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 317.4226

Ref: IN-DA003UMF

Tetrabenazine

CAS: 58-46-8

Tetrabenazine

Formula: C₁₉H₂₇NO₃

Purezza: ≥98%

Peso molecolare: 317.42

Ref: 54-BUP15812

Tetrabenazine

CAS: 58-46-8

Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders.

Formula: C₁₉H₂₇NO₃

Purezza: 98% - 99.91%

Colore e forma: Solid

Peso molecolare: 317.42

Ref: TM-T0719

Tetrabenazine

CAS: 58-46-8

Tetrabenazine

Formula: C₁₉H₂₇NO₃

Purezza: 99%

Peso molecolare: 317.42

Ref: 54-OR1028221

Tetrabenazine

CAS: 58-46-8

Formula: C₁₉H₂₇NO₃

Colore e forma: White To Off-White Solid

Peso molecolare: 317.43

Ref: 4Z-T-781

Tetrabenazine

CAS: 58-46-8

Formula: C₁₉H₂₇NO₃

Peso molecolare: 317.42

Ref: 7W-GK0293

Tetrabenazine-d7

CAS: 58-46-8

Formula: C₁₉H₂₀D₇NO₃

Colore e forma: White To Off-White Solid

Peso molecolare: 324.47

Ref: 4Z-T-782

Tetrabenazine

CAS: 58-46-8

Formula: C₁₉H₂₇NO₃

Colore e forma: Neat

Peso molecolare: 317.42

Ref: 86-MM1633.01

Tetrabenazine

CAS: 58-46-8

Formula: C₁₉H₂₇NO₃

Peso molecolare: 317.43

Ref: ST-EA-CP-T104000

Tetrabenazine - Bio-X ™

Prodotto controllato

CAS: 58-46-8

Tetrabenazine is a drug that has been used for the treatment of Parkinson's disease. It acts by inhibiting dopamine release and reducing the activity of nerve cells in the brain. Tetrabenazine Bio-X is used to treat dyskinesias, that are abnormal and involuntary muscle movements by inhibiting the monoamine transporter (VMAT2). Tetrabenazine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use."

Formula: C₁₉H₂₇NO₃

Purezza: Min. 99 Area-%

Colore e forma: White Powder

Peso molecolare: 317.42 g/mol

Ref: 3D-BT164463

3-ISOBUTYL-9,10-DIMETHOXY-3,4,6,7-TETRAHYDRO-1H-PYRIDO[2,1-A]ISOQUINOLIN-2(11BH)-ONE

CAS: 58-46-8

Formula: C₁₉H₂₇NO₃

Purezza: 97.0%

Colore e forma: Solid

Peso molecolare: 317.429

Ref: 10-F301460

Tetrabenazine

Prodotto controllato

CAS: 58-46-8

Applications Dopamine depleting agent. An antidyskinetic; antipsychotic.
References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),

Formula: C₁₉H₂₇NO₃

Colore e forma: Neat

Peso molecolare: 317.42

Ref: TR-T284000

Tetrabenazine

Prodotto controllato

CAS: 58-46-8

Tetrabenazine is a drug that has been used for the treatment of Parkinson's disease. It acts by inhibiting dopamine release and reducing the activity of nerve cells in the brain. Tetrabenazine Bio-X is used to treat dyskinesias, that are abnormal and involuntary muscle movements by inhibiting the monoamine transporter (VMAT2).

Formula: C₁₉H₂₇NO₃

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 317.42 g/mol

Ref: 3D-FT28060