CAS 58-94-6

clorotiazide

Descrizione:

clorotiazide è un diuretico tiazidico comunemente usato nel trattamento dell'ipertensione e dell'edema associato a insufficienza cardiaca o disturbi renali. La sua formula chimica è C7H6ClN3O4S e presenta un gruppo sulfonamide, caratteristico dei diuretici tiazidici. clorotiazide agisce inibendo il riassorbimento del sodio nel tubulo contorto distale del nefrone, portando a un aumento dell'escrezione di sodio e acqua, riducendo così il volume del sangue e abbassando la pressione sanguigna. La sostanza è tipicamente somministrata per via orale ed è nota per il suo inizio d'azione relativamente rapido. clorotiazide può anche avere effetti sull'equilibrio elettrolitico, in particolare sul potassio, il che può portare a ipokaliemia se non monitorato. È importante considerare i potenziali effetti collaterali, tra cui vertigini, disturbi gastrointestinali e reazioni allergiche. Come per qualsiasi farmaco, il suo uso dovrebbe essere guidato da un professionista sanitario, tenendo conto dei fattori individuali del paziente e delle potenziali interazioni farmacologiche.

Formula: C₇H₆ClN₃O₄S₂

InChI: InChI=1/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H2,9,12,13)(H,10,11,14,15)

InChI key: InChIKey=JBMKAUGHUNFTOL-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(=CC(Cl)=C(S(N)(=O)=O)C2)NC=N1

Sinonimi:

• 2-Chloro-1,2,4-Benzothiadiazine-7-Sulphonamide 1,1-Dioxide
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide
• 6-Chloro-1-Hydroxy-1Lambda~4~,2,4-Benzothiadiazine-7-Sulfonamide 1-Oxide
• 6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
• 6-Chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• 6-Chloro-7-sulfamyl-1,2,4-benzothiadiazine 1,1-dioxide
• 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Alurene
• Chlorosal
• Chlorothiazid
• Chlorthiazide
• Chlorurit
• Chlotride
• Clorotiazida
• Clotride
• Diuresal
• Diuril
• Diuril Boluses
• Diurilix
• Diurite
• Diutrid
• Flumen
• Minzil
• Neo-Dema
• Nsc 25693
• Salisan
• Salunil
• Saluretil
• Saluric
• Thiazide
• Urinex
• Warduzide
• Yadalan
• Chlorothiazide
• Chlortiazid
• Chlrosal
• Aldoclor

Chlorothiazide

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 295.71

Ref: 3B-C2259

Chlorothiazide

CAS: 58-94-6

Colore e forma: Neat

Ref: 61-FOR0011.03

CHLOROTHIAZIDE CRS

CAS: 58-94-6

CHLOROTHIAZIDE CRS

Formula: C₇H₆ClN₃O₄S₂

Peso molecolare: 295.7232

Ref: 41-C1700000

Chlorothiazide

CAS: 58-94-6

Chlorothiazide

Colore e forma: White. To. Off-White

Ref: 47-76

Chlorothiazide

CAS: 58-94-6

Sulfonamides used as drugs

Formula: C₇H₆ClN₃O₄S₂

Colore e forma: White Powder

Peso molecolare: 294.94883

Ref: 45-1121005

Chlorothiazide (Hydrochlorothiazide EP Impurity A)

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Peso molecolare: 295.71

Ref: 4Z-C-449001

Chlorothiazide

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Purezza: ≥ 97.0%

Colore e forma: White to off-white powder or crystals

Peso molecolare: 295.72

Ref: 7W-GK7819

Chlorothiazide

CAS: 58-94-6

Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.

Formula: C₇H₆ClN₃O₄S₂

Purezza: 98.46% - 98.91%

Colore e forma: White Solid

Peso molecolare: 295.72

Ref: TM-T0677

Chlorothiazide

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Colore e forma: Neat

Peso molecolare: 295.72

Ref: 04-C11510700

Chlorothiazide (Standard)

CAS: 58-94-6

Chlorothiazide (Standard) is the standard substance of Chlorothiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.

Formula: C₇H₆ClN₃O₄S₂

Peso molecolare: 295.72

Ref: TM-TMSM-0717

Chlorothiazide

Prodotto controllato

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Colore e forma: White To Off-White

Peso molecolare: 295.72

Ref: 86-MM0011.03

Chlorothiazide 100 µg/mL in Acetonitrile

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Colore e forma: Single Solution

Peso molecolare: 295.72

Ref: 04-A11510700AL-100

Chlorothiazide

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Peso molecolare: 295.71

Ref: ST-EA-CP-C269000

Hydrochlorothiazide EP Impurity A

CAS: 58-94-6

Formula: C₇H₆ClN₃O₄S₂

Peso molecolare: 295.71

Ref: ST-EA-CP-H3001

Chlorothiazide

Prodotto controllato

CAS: 58-94-6

Impurity Hydrochlorothiazide EP Impurity A
Applications Diuretic; antihypertensive. Hydrochlorothiazide EP Impurity A.
References Brittain, H.G., et al.: Anal. Profiles Drug Subs., 18, 33 (1989), Yoshida, F., et al.: J. Med. Chem., 43, 2575 (2000), Luan, F., et al.: Chem. Res. Toxicol., 18, 198 (2005), Si, H., et al.: Bioorg. Med. Chem., 14, 4834 (2006),

Formula: C₇H₆ClN₃O₄S₂

Colore e forma: Neat

Peso molecolare: 295.72

Ref: TR-C380000

Chlorothiazide

Prodotto controllato

CAS: 58-94-6

Chlorothiazide is a diuretic that is a thiazide. It is used in combination preparations to treat high blood pressure (hypertension) and congestive heart failure. Chlorothiazide is also used to reduce the amount of fluid in the body (edema) and as an adjuvant therapy for kidney disease. This drug has been shown to be safe at therapeutic doses, although it may have some toxic effects on liver function. The toxicity studies on chlorothiazide have demonstrated no carcinogenic effects in either animals or humans, but there are reports of some skin cancer cases among people who have taken this drug for many years.

Formula: C₇H₆ClN₃O₄S₂

Purezza: Min. 95%

Colore e forma: White/Off-White Solid

Peso molecolare: 295.73 g/mol

Ref: 3D-FC20399

6-chloro-1,1-dioxo-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide

CAS: 58-94-6

Purezza: 95%

Peso molecolare: 295.7099915

Ref: 10-F814386