CAS 5968-70-7

Acido acetil-β-boswellico

Descrizione:

Acido acetil-β-boswellico è un composto triterpenoide pentaciclico derivato dalla resina dell'albero Boswellia serrata, comunemente noto per le sue proprietà antinfiammatorie e analgesiche. Questo composto è caratterizzato dalla sua unica struttura chimica, che include un sistema di anelli fusi che contribuisce alla sua attività biologica. Acido acetil-β-boswellico mostra una gamma di effetti farmacologici, inclusa l'inibizione dei mediatori pro-infiammatori, rendendolo di interesse nel trattamento di condizioni come l'artrite e altre malattie infiammatorie. Il suo meccanismo d'azione coinvolge la modulazione di varie vie di segnalazione, inclusa l'inibizione della sintesi dei leucotrieni. Inoltre, questo composto ha mostrato potenziale nella promozione dell'apoptosi nelle cellule tumorali e potrebbe possedere proprietà neuroprotettive. A causa della sua origine naturale, è spesso considerato un'alternativa più sicura ai farmaci anti-infiammatori sintetici. Tuttavia, sono necessarie ulteriori ricerche per comprendere appieno la sua efficacia, le dosi ottimali e i potenziali effetti collaterali nelle applicazioni cliniche.

Formula: C₃₂H₅₀O₄

InChI: InChI=1S/C32H50O4/c1-19-11-14-28(4)17-18-30(6)22(26(28)20(19)2)9-10-23-29(5)15-13-25(36-21(3)33)32(8,27(34)35)24(29)12-16-31(23,30)7/h9,19-20,23-26H,10-18H2,1-8H3,(H,34,35)/t19-,20+,23-,24-,25-,26+,28-,29-,30-,31-,32-/m1/s1

InChI key: InChIKey=YJBVHJIKNLBFDX-MQURJEHKSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)([C@](C(O)=O)(C)[C@H](OC(C)=O)CC3)[H])(CC=C4[C@@]2(C)CC[C@]5(C)[C@]4([C@@H](C)[C@H](C)CC5)[H])[H]

Sinonimi:

• (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid
• (3Α)-3-(Acetyloxy)Urs-12-En-24-Oic Acid
• (3α)-3-Acetoxyurs-12-en-24-oic acid
• (3α,4β)-3-(Acetyloxy)urs-12-en-23-oic acid
• 3-O-Acetyl-β-boswellic acid
• 3α-Acetoxyurs-12-en-24-oic acid
• 3α-Acetyl-β-boswellic acid
• Acetyl-β-boswellic acid
• Beta-Boswellic Acid,3-Acetyl
• Urs-12-En-24-Oic Acid, 3-(Acetyloxy)-, (3Α)-
• Urs-12-en-23-oic acid, 3-(acetyloxy)-, (3α,4β)-
• Urs-12-en-24-oic acid, 3α-hydroxy-, acetate

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-Acetyl-β-boswellic acid

Formula: C₃₂H₅₀O₄

Purezza: ≥95%

Peso molecolare: 498.74

Ref: 54-BUP02661

3-O-Acetyl-β-boswellic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Peso molecolare: 498.74

Ref: 7W-GL8130

(3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-Acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 498.7370

Ref: IN-DA003AJD

3-Acetyl-β-boswellic acid (Standard)

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid (Standard) is a reference standard for research and analysis in studies involving 3-Acetyl-beta-boswellic acid. 3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC₅₀ values ranging from 0.6 to 7.1 microM.

Formula: C₃₂H₅₀O₄

Peso molecolare: 498.737

Ref: TM-TMSM-0187

3-O-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-O-Acetyl-beta-boswellic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₂H₅₀O₄

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 498.75

Ref: 11-2314S

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Purezza: 95%~99%

Peso molecolare: 498.748

Ref: BP-BPF0530

3-O-Acetyl-beta-boswellic Acid

CAS: 5968-70-7

Applications 3-O-Acetyl-beta-boswellic acid possesses anti-inflammatory potential on key inflammatory mediators, TNF-α and IL-6. Main bioactive components of frankincense which is a fragrant resin obtained from plants of the genus Boswellia, acts as a cytotoxic agents. It is also a non-competitive 5-lipoxygenase and topoisomerase I and IIa.
References Sharma, S., et al.: Bioorg. Med. Chem. Lett., 26, 695-698 (2016); Csuk, R., et al.: Tetrahedron, 71, 2025-2034 (2015); Csuk, R., et al.: Eur. J. Med. Chem., 100, 98-105 (2015);

Formula: C₃₂H₅₀O₄

Colore e forma: Neat

Peso molecolare: 498.74

Ref: TR-A177770

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner.

Formula: C₃₂H₅₀O₄

Purezza: 95.62% - 99.17%

Colore e forma: Solid

Peso molecolare: 498.737

Ref: TM-TN1258

3-O-Acetyl-β-boswellic Acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Peso molecolare: 498.75

Ref: 4Z-B-134002

3-O-Acetyl β-boswellic acid

CAS: 5968-70-7

Carboxylic acid with alcohol function

Formula: C₃₂H₅₀O₄

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 498.75

Ref: 5G-89152

3-Acetyl-beta-boswellic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Peso molecolare: 498.7

Ref: BE-RMCB180002

Acetyl β-boswellic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Peso molecolare: 498.7

Ref: BE-RMT17834

3-Acetyl-beta-boswellic acid

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid is a pentacyclic triterpenoid compound, which is derived from the resin of the Boswellia serrata tree. It exhibits significant biological activity, mainly due to its anti-inflammatory properties. The mode of action primarily involves the inhibition of 5-lipoxygenase, an enzyme crucial in the biosynthesis of leukotrienes, which are mediators in inflammatory and allergic responses. Additionally, it has been shown to modulate various signaling pathways and transcription factors involved in inflammation.

Formula: C₃₂H₅₀O₄

Purezza: Min. 95%

Peso molecolare: 498.74 g/mol

Ref: 3D-FA65590