CAS 633-65-8

Cloridrato di berberina

Descrizione:

Cloridrato di berberina è un sale di ammonio quaternario derivato dall'alcaloide berberina, che si trova in varie piante, tra cui goldenseal e agrifoglio. È caratterizzato dal suo colore giallo brillante ed è noto per il suo sapore amaro. La sostanza è solubile in acqua e alcol, rendendola adatta per varie formulazioni farmaceutiche. Cloridrato di berberina presenta una gamma di attività biologiche, comprese proprietà antimicrobiche, anti-infiammatorie e antidiabetiche, che hanno suscitato interesse sia nella medicina tradizionale che in quella moderna. Il suo meccanismo d'azione implica la modulazione di diversi percorsi cellulari, inclusi quelli relativi al metabolismo del glucosio e alla regolazione dei lipidi. Inoltre, la berberina è stata studiata per i suoi potenziali effetti sulla salute cardiovascolare e sulla microbiota intestinale. A causa dei suoi effetti farmacologici diversificati, Cloridrato di berberina è spesso utilizzato in integratori alimentari e rimedi erboristici, sebbene il suo uso debba essere affrontato con cautela a causa delle potenziali interazioni con altri farmaci e degli effetti collaterali. In generale, Cloridrato di berberina è un composto di notevole interesse sia in contesti di ricerca che terapeutici.

Formula: C₂₀H₁₈ClNO₄

InChI: InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;

InChI key: InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M

SMILES: O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC.[Cl-]

Sinonimi:

• 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1)
• 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
• Berberberberine hydrochloride n-hydrate
• Berberine IR
• Berberine chloride
• Berberine hcl
• Berberinium chloride
• Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
• NSC 163088
• NSC 646666
• ine HCl
• Berberine hydrochloride
• Berberine chloride form,Natural Yellow18
• 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniuchlori
• Berberine chloride form
• Berberine chloride ,98%
• Kyoberin
• Berberine hydrochloride hydrate,97%
• Berberdine HCl
• BERBERINECHLORIDE(SH)
• 9,10-Dimethoxy-5,6-dihydro-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• BERBERINE CHLORIDE(AHP)
• 9,10-Dimethoxy-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• berberiniumchloride
• NATURAL YELLOW 18
• BERBERIN HCL
• UMBELLATINE
• TIMTEC-BB SBB006488
• LABOTEST-BB LT00440956
• C.I.Natural Yellow 18
• Berberine Chloride, JP
• 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
• BBR
• BERBERINE HYDROCHLORIDE N-HYDRATE
• 7,8,13,13a-Tetradehydro-9,10-diMethoxy-2,3-(Methylenedioxy)berbiniuM Chloride
• Berberin chloride dihydrate
• Berberinehydrochloride，Berberine chloride form
• 3)benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)(c
• 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
• NATURAL YELLOW 18 CHLORIDE
• Berberine chloride (TN)
• CI 75160

Berberine Chloride Hydrate

CAS: 141433-60-5, 2086-83-1, 633-65-8

Formula: C₂₀H₁₈ClNO₄·xH₂O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Yellow to Orange powder to crystaline

Peso molecolare: 371.82 (as Anhydrous)

Ref: 3B-B0450

Berberine chloride

CAS: 633-65-8

Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical r

Formula: C₂₀H₁₈ClNO₄

Colore e forma: Yellow to orange, Powder

Peso molecolare: 371.82

Ref: 02-J62311

Berberine chloride

CAS: 633-65-8

Berberine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₀H₁₈ClNO₄

Purezza: (HPLC) ≥95%

Colore e forma: Powder

Peso molecolare: 371.82

Ref: 11-0601

BERBERINE CHLORIDE CRS

CAS: 633-65-8

BERBERINE CHLORIDE CRS

Formula: C₂₀H₁₉ClNO₄

Peso molecolare: 372.8216

Ref: 41-Y0001149

Berberine chloride

CAS: 633-65-8

Berberine chloride

Formula: C₂₀H₁₈NO₄

Purezza: 77.7%

Colore e forma: White

Peso molecolare: 336.12358

Ref: 47-1108

Berberine chloride

CAS: 633-65-8

Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.

Formula: C₂₀H₁₈ClNO₄

Purezza: 99.47% - 99.93%

Colore e forma: Yellow Crystalline Powder

Peso molecolare: 371.80

Ref: TM-T0461

Berberine hydrochloride

CAS: 633-65-8

Formula: C₂₀H₁₈ClNO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 371.8142

Ref: IN-DA00IB6S

Berberine chloride

CAS: 633-65-8

Berberine chloride

Purezza: ≥98%

Peso molecolare: 371.8g/mol

Ref: 54-BUP19732

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride

Purezza: 98%

Peso molecolare: 371.81g/mol

Ref: 54-OR1028076

Berberine hydrochloride

CAS: 633-65-8

Formula: C₂₀H₁₈ClNO₄

Purezza: 96.0 - 104.0 % (dried basis)

Colore e forma: Yellow or orange powder

Peso molecolare: 371.82

Ref: 7W-GK8292

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride (berberine), a natural plant alkaloid derived from Chinese herbal medicine, is characterized by diverse pharmacological effects, such as anticancer and lower elevated blood glucose, it can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation.

Formula: C₂₀H₁₈ClNO₄

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 371.817

Ref: BP-BP0252

Berberine Chloride

Prodotto controllato

CAS: 633-65-8

Formula: C₂₀H₁₈NO₄·Cl

Colore e forma: Neat

Peso molecolare: 371.81

Ref: 86-MM1632.00

Berberine chloride

Prodotto controllato

CAS: 633-65-8

Formula: C₂₀H₁₈NO₄·Cl

Colore e forma: Neat

Peso molecolare: 371.81

Ref: 04-C10573950

Berberine Hydrochloride-d6

Prodotto controllato

CAS: 633-65-8

Stability Hygroscopic
Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Formula: C₂₀H₁₂D₆ClNO₄

Colore e forma: Neat

Peso molecolare: 377.85

Ref: TR-B318152

Berberine Chloride Hydrate

Prodotto controllato

CAS: 633-65-8

Stability Hygroscopic
Applications An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Formula: C₂₀H₁₈NO₄·Cl

Colore e forma: Light Yellow To Yellow

Peso molecolare: 371.81

Ref: TR-B318150

Berberine hydrochloride

CAS: 633-65-8

Formula: C₂₀H₁₈ClNO₄

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 371.82

Ref: 10-F516404

Berberine Chloride

CAS: 633-65-8

Formula: C₂₀H₁₈NO₄Cl

Peso molecolare: 336.4 : 35.5

Ref: ST-EA-CP-B118001

Berberine chloride

CAS: 633-65-8

Activates AMPK enzyme; anti-inflammatory; anti-diabetic

Formula: C₂₀H₁₈NO₄•Cl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 371.81 g/mol

Ref: 3D-FB64955

Berberine Chloride

CAS: 633-65-8

Colore e forma: Neat

Ref: 61-FOR1632.00