CAS 633-65-8

Cloridrato di berberina

Descrizione:

Cloridrato di berberina è un sale di ammonio quaternario derivato dall'alcaloide berberina, che si trova in varie piante, tra cui goldenseal e agrifoglio. È caratterizzato dal suo colore giallo brillante ed è noto per il suo sapore amaro. La sostanza è solubile in acqua e alcol, rendendola adatta per varie formulazioni farmaceutiche. Cloridrato di berberina presenta una gamma di attività biologiche, comprese proprietà antimicrobiche, anti-infiammatorie e antidiabetiche, che hanno suscitato interesse sia nella medicina tradizionale che in quella moderna. Il suo meccanismo d'azione implica la modulazione di diversi percorsi cellulari, inclusi quelli relativi al metabolismo del glucosio e alla regolazione dei lipidi. Inoltre, la berberina è stata studiata per i suoi potenziali effetti sulla salute cardiovascolare e sulla microbiota intestinale. A causa dei suoi effetti farmacologici diversificati, Cloridrato di berberina è spesso utilizzato in integratori alimentari e rimedi erboristici, sebbene il suo uso debba essere affrontato con cautela a causa delle potenziali interazioni con altri farmaci e degli effetti collaterali. In generale, Cloridrato di berberina è un composto di notevole interesse sia in contesti di ricerca che terapeutici.

Formula: C₂₀H₁₈ClNO₄

InChI: InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;

InChI key: InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M

SMILES: O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC.[Cl-]

Sinonimi:

• 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1)
• 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
• Berberberberine hydrochloride n-hydrate
• Berberine IR
• Berberine chloride
• Berberine hcl
• Berberinium chloride
• Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
• NSC 163088
• NSC 646666
• ine HCl
• Berberine hydrochloride
• Berberine chloride form,Natural Yellow18
• 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniuchlori
• Berberine chloride form
• Berberine chloride ,98%
• Kyoberin
• Berberine hydrochloride hydrate,97%
• Berberdine HCl
• BERBERINECHLORIDE(SH)
• 9,10-Dimethoxy-5,6-dihydro-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• BERBERINE CHLORIDE(AHP)
• 9,10-Dimethoxy-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• berberiniumchloride
• NATURAL YELLOW 18
• BERBERIN HCL
• UMBELLATINE
• TIMTEC-BB SBB006488
• LABOTEST-BB LT00440956
• C.I.Natural Yellow 18
• Berberine Chloride, JP
• 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
• BBR
• BERBERINE HYDROCHLORIDE N-HYDRATE
• 7,8,13,13a-Tetradehydro-9,10-diMethoxy-2,3-(Methylenedioxy)berbiniuM Chloride
• Berberin chloride dihydrate
• Berberinehydrochloride，Berberine chloride form
• 3)benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)(c
• 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
• NATURAL YELLOW 18 CHLORIDE
• Berberine chloride (TN)
• CI 75160

Berberine Chloride Hydrate

CAS: 141433-60-5, 2086-83-1, 633-65-8

Formula: C₂₀H₁₈ClNO₄·xH₂O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Yellow to Orange powder to crystaline

Peso molecolare: 371.82 (as Anhydrous)

Ref: 3B-B0450

Berberine chloride

CAS: 633-65-8

Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical r

Formula: C₂₀H₁₈ClNO₄

Colore e forma: Yellow to orange, Powder

Peso molecolare: 371.82

Ref: 02-J62311

Berberine chloride

CAS: 633-65-8

Berberine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₀H₁₈ClNO₄

Purezza: (HPLC) ≥95%

Colore e forma: Powder

Peso molecolare: 371.82

Ref: 11-0601

BERBERINE CHLORIDE CRS

CAS: 633-65-8

BERBERINE CHLORIDE CRS

Formula: C₂₀H₁₉ClNO₄

Peso molecolare: 372.8216

Ref: 41-Y0001149

Berberine chloride

CAS: 633-65-8

Berberine chloride

Formula: C₂₀H₁₈NO₄

Purezza: 77.7%

Colore e forma: White

Peso molecolare: 336.12358

Ref: 47-1108

Berberine hydrochloride

CAS: 633-65-8

Formula: C₂₀H₁₈ClNO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 371.8142

Ref: IN-DA00IB6S

Berberine chloride

CAS: 633-65-8

Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.

Formula: C₂₀H₁₈ClNO₄

Purezza: 99.47% - 99.93%

Colore e forma: Yellow Crystalline Powder

Peso molecolare: 371.80

Ref: TM-T0461

Berberine chloride

CAS: 633-65-8

Berberine chloride

Formula: C₂₀H₁₈ClNO₄

Purezza: ≥98%

Peso molecolare: 371.8

Ref: 54-BUP19732

Berberine hydrochloride

CAS: 633-65-8

Formula: C₂₀H₁₈ClNO₄

Purezza: 96.0 - 104.0 % (dried basis)

Colore e forma: Yellow or orange powder

Peso molecolare: 371.82

Ref: 7W-GK8292

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride

Formula: C₂₀H₁₈ClNO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 371.81

Ref: 54-OR1028076

Berberine chloride (Standard)

CAS: 633-65-8

Berberine chloride (Standard) is a reference standard for research and analysis in studies involving Berberine chloride. Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal and parasitic infections and an anti-diarrheal.

Formula: C₂₀H₁₈ClNO₄

Colore e forma: Solid

Peso molecolare: 371.80

Ref: TM-TMSM-2973

Berberine Chloride

Prodotto controllato

CAS: 633-65-8

Formula: C₂₀H₁₈NO₄·Cl

Colore e forma: Neat

Peso molecolare: 371.81

Ref: 86-MM1632.00

Berberine chloride

Prodotto controllato

CAS: 633-65-8

Formula: C₂₀H₁₈NO₄·Cl

Colore e forma: Neat

Peso molecolare: 371.81

Ref: 04-C10573950

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride (berberine), a natural plant alkaloid derived from Chinese herbal medicine, is characterized by diverse pharmacological effects, such as anticancer and lower elevated blood glucose, it can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation.

Formula: C₂₀H₁₈ClNO₄

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 371.817

Ref: BP-BP0252

Berberine Hydrochloride-d6

Prodotto controllato

CAS: 633-65-8

Stability Hygroscopic
Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Formula: C₂₀H₁₂D₆ClNO₄

Colore e forma: Neat

Peso molecolare: 377.85

Ref: TR-B318152

Berberine Chloride Hydrate

Prodotto controllato

CAS: 633-65-8

Stability Hygroscopic
Applications An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Formula: C₂₀H₁₈NO₄·Cl

Colore e forma: Neat

Peso molecolare: 371.81

Ref: TR-B318150

Berberine hydrochloride

CAS: 633-65-8

Formula: C₂₀H₁₈ClNO₄

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 371.82

Ref: 10-F516404

Berberine Chloride

CAS: 633-65-8

Formula: C₂₀H₁₈NO₄Cl

Peso molecolare: 336.4 : 35.5

Ref: ST-EA-CP-B118001

Berberine chloride

CAS: 633-65-8

Activates AMPK enzyme; anti-inflammatory; anti-diabetic

Formula: C₂₀H₁₈NO₄•Cl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 371.81 g/mol

Ref: 3D-FB64955