CAS 63610-08-2

Indobufene

Descrizione:

Indobufene è un farmaco antinfiammatorio non steroideo (FANS) utilizzato principalmente per le sue proprietà analgesiche e antinfiammatorie. È caratterizzato dalla sua capacità di inibire le enzimi cicloossigenasi, che svolgono un ruolo cruciale nella sintesi delle prostaglandine, riducendo così il dolore e l'infiammazione. Indobufene è spesso utilizzato nel trattamento di varie condizioni, tra cui artrite e altri disturbi infiammatori. Il composto è tipicamente somministrato per via orale ed è noto per il suo inizio d'azione relativamente rapido. La sua struttura chimica include un gruppo fenile e un moiety di acido butirrico, contribuendo ai suoi effetti farmacologici. Indobufene è anche noto per i suoi potenziali effetti collaterali, che possono includere disturbi gastrointestinali e rischi cardiovascolari, simili ad altri FANS. Come con qualsiasi farmaco, è essenziale utilizzare Indobufene sotto supervisione medica per gestire il dosaggio e monitorare le reazioni avverse. In generale, Indobufene rappresenta un'opzione preziosa nella gestione del dolore e dell'infiammazione, con un profilo specifico che lo distingue da altri FANS.

Formula: C₁₈H₁₇NO₃

InChI: InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)

InChI key: InChIKey=AYDXAULLCROVIT-UHFFFAOYSA-N

SMILES: O=C1N(CC=2C1=CC=CC2)C3=CC=C(C(C(O)=O)CC)C=C3

Sinonimi:

• (2R)-2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid
• 1-Oxo-2-[p-[(α-ethyl)carboxymethyl]phenyl]isoindoline
• 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid
• 2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid
• 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric acid
• 4-(1,3-Dihydro-1-oxo-(2H)-isoindol-2-yl)-alpha-ethylbenzeneacetic acid
• 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid
• Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-
• Ibustrin
• K 2930
• K 3920

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Purezza: >98.0%(GC)(T)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 295.34

Ref: 3B-I1178

(2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 295.3325

Ref: IN-DA01CBW2

Indobufen

CAS: 63610-08-2

Indobufen

Formula: C₁₈H₁₇NO₃

Purezza: ≥98%

Peso molecolare: 295.33

Ref: 54-BUP13709

Indobufen

CAS: 63610-08-2

Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor.

Formula: C₁₈H₁₇NO₃

Purezza: 99.27% - 99.44%

Colore e forma: White Solid

Peso molecolare: 295.33

Ref: TM-T15577

2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid

CAS: 63610-08-2

2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid

Formula: C₁₈H₁₇NO₃

Purezza: >99%

Peso molecolare: 295.33

Ref: 54-OR1029819

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Peso molecolare: 295.33

Ref: 7W-GP5189

Indobufen-d5

CAS: 63610-08-2

Formula: C₁₈H₁₂D₅NO₃

Colore e forma: White To Off-White Solid

Peso molecolare: 300.37

Ref: 4Z-I-5110

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Colore e forma: White To Off-White Solid

Peso molecolare: 295.34

Ref: 4Z-I-511

Indobufen

CAS: 63610-08-2

Indobufen is a drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to be effective in treating infectious diseases, including malaria and bacterial infections. Indobufen has been shown to inhibit the production of prostaglandin E2 (PGE2) in an experimental model at low doses. This inhibition leads to reduced levels of PGE2 receptor activity and decreased enzyme activities such as cyclooxygenase and lipoxygenase, which are involved in inflammation. This drug also inhibits platelet aggregation and increases bleeding time. The effects of indobufen on human pharmacokinetics have been studied using human serum and platelet samples from healthy volunteers. Indobufen is rapidly absorbed, with a half-life of 1 hour, and it is metabolized by cytochrome P450 (CYP450). Indobufen has also been shown to increase cardiac contractility without affecting heart rate or blood pressure levels.

Formula: C₁₈H₁₇NO₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 295.33 g/mol

Ref: 3D-FI37690

Indobufen

CAS: 63610-08-2

2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid

Formula: C₁₈H₁₇NO₃

Purezza: 99%

Peso molecolare: 295.33

Ref: IN-DG41901

Indobufen

Prodotto controllato

CAS: 63610-08-2

Applications Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.
References Diener, H., et al.: J. Neurol. Sci., 143, 1 (1996), Brainin, M., et al.: Eur. J. Neurol., 7, 5 (2005), Culebras, A., et al.: Neurology, 62, 1073 (2004), Lopez, A., et al.: Lancet, 367, 1747 (2006),

Formula: C₁₈H₁₇NO₃

Colore e forma: Neat

Peso molecolare: 295.33

Ref: TR-I576500

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Peso molecolare: 295.34

Ref: ST-EA-CP-I87000