CAS 67915-31-5

Terconazolo

Descrizione:

Terconazolo è un agente antifungino utilizzato principalmente nel trattamento delle infezioni vaginali da lieviti causate da specie di Candida. Appartiene alla classe degli antifungini triazolici, che funzionano inibendo la sintesi dell'ergosterolo, un componente essenziale delle membrane cellulari fungine, interrompendo così la loro integrità e portando alla morte cellulare. Terconazolo viene tipicamente somministrato come crema topica o supposta vaginale, consentendo un trattamento localizzato con un'assorbimento sistemico minimo. La sostanza è caratterizzata dalla sua relativamente bassa solubilità in acqua, ma è solubile in solventi organici, il che aiuta nella sua formulazione. Terconazolo mostra un ampio spettro di attività contro vari funghi, in particolare Candida albicans. La sua farmacocinetica indica una durata d'azione prolungata, rendendolo efficace con meno dosi. Gli effetti collaterali sono generalmente lievi e possono includere irritazione locale o reazioni allergiche. In generale, Terconazolo è un'opzione preziosa nella terapia antifungina, in particolare per i pazienti che cercano un trattamento localizzato per le infezioni vaginali.

Formula: C₂₆H₃₁Cl₂N₅O₃

InChI: InChI=1/C26H31Cl2N5O3/c1-19(2)31-9-11-32(12-10-31)21-4-6-22(7-5-21)34-14-23-15-35-26(36-23,16-33-18-29-17-30-33)24-8-3-20(27)13-25(24)28/h3-8,13,17-19,23H,9-12,14-16H2,1-2H3/t23-,26-/s2

InChI key: InChIKey=BLSQLHNBWJLIBQ-MKNUCDGGNA-N

SMILES: C([C@]1(O[C@@H](COC2=CC=C(C=C2)N3CCN(C(C)C)CC3)CO1)C4=C(Cl)C=C(Cl)C=C4)N5C=NC=N5

Sinonimi:

• (.+-.)-Terconazole
• Fungistat
• Gyno-Terazol
• Nsc 331942
• Piperazine, 1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, cis-
• R 42470
• Terazol
• Terazol Cream & Suppositories
• Terconazol
• Tercospor
• Termayazole
• Triaconazole
• rel-1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)piperazine
• 1-(4-{[(4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-(propan-2-yl)piperazine
• Terconagole
• 1-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-(propan-2-yl)piperazine
• TERCONAZOLE USP(CRM STANDARD)
• 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-(propan-2-yl)piperazine
• 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-propan-2-yl-piperazine
• TERCONAZOLE EPT(CRM STANDARD)
• Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, rel-

TERCONAZOLE CRS

CAS: 67915-31-5

TERCONAZOLE CRS

Ref: 41-T0060000

Terconazole

CAS: 67915-31-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₆H₃₁Cl₂N₅O₃

Colore e forma: White Off-White Powder

Peso molecolare: 531.1804

Ref: 45-1643703

1-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-Yl)Methyl)-2-(2,4-Dichlorophenyl)-1,3-Dioxolan-4-Yl)Methoxy)Phenyl)-4-Isopropylpiperazine

CAS: 67915-31-5

1-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-Yl)Methyl)-2-(2,4-Dichlorophenyl)-1,3-Dioxolan-4-Yl)Methoxy)Phenyl)-4-Isopropylpiperazine

Formula: C₂₆H₃₁Cl₂N₅O₃

Purezza: 97%

Peso molecolare: 532.46

Ref: 54-OR1025957

Piperazine,1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, rel-

CAS: 67915-31-5

Formula: C₂₆H₃₁Cl₂N₅O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 532.4620

Ref: IN-DA00IBRL

Terconazole

CAS: 67915-31-5

Formula: C₂₆H₃₁Cl₂N₅O₃

Peso molecolare: 532.46

Ref: 7W-GP4833

Terconazole

CAS: 67915-31-5

Terconazole

Formula: C₂₆H₃₁Cl₂N₅O₃

Purezza: ≥98%

Colore e forma: Solid

Peso molecolare: 532.46

Ref: 54-BUP13962

Terconazole

CAS: 67915-31-5

Formula: C₂₆H₃₁Cl₂N₅O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 532.47

Ref: 4Z-T-142009

Terconazole

Prodotto controllato

CAS: 67915-31-5

Formula: C₂₆H₃₁Cl₂N₅O₃

Colore e forma: Neat

Peso molecolare: 532.46

Ref: 04-C17320500

Terconazole

Prodotto controllato

CAS: 67915-31-5

Formula: C₂₆H₃₁Cl₂N₅O₃

Colore e forma: Neat

Peso molecolare: 532.46

Ref: 86-MM1286.00

Terconazole

CAS: 67915-31-5

Terconazole, a triazole antifungal, disrupts fungal cell walls by inhibiting ergosterol synthesis, active against Candida.

Formula: C₂₆H₃₁Cl₂N₅O₃

Purezza: 98% - 99.60%

Colore e forma: Solid

Peso molecolare: 532.46

Ref: TM-T2213

Terconazole-d8

CAS: 67915-31-5

Formula: C₂₆H₂₃D₈Cl₂N₅O₃

Peso molecolare: 540.51

Ref: 4Z-T-142010

Terconazole

CAS: 67915-31-5

Formula: C₂₆H₃₁Cl₂N₅O₃

Peso molecolare: 532.47

Ref: ST-EA-CP-T135000

Terconazole

CAS: 67915-31-5

Terconazole is an azole antifungal agent with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for treating vaginal yeast infections.

Formula: C₂₆H₃₁Cl₂N₅O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 532.46 g/mol

Ref: 3D-FT35141

Terconazole

CAS: 67915-31-5

Formula: C₂₆H₃₁Cl₂N₅O₃

Purezza: 97%

Peso molecolare: 532.47

Ref: 10-F547226

Terconazole

Prodotto controllato

CAS: 67915-31-5

Applications Terconazole belongs to a new chemical class of antifungal agents, the triazoles. Terconazole has a far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450 and is used as topical treatment of mycotic vaginitis. Terconazole may also be used in vitro as a potent antifungal agent to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of Candida albicans.
References Cauwenbergh, G., Vanden Bossch H.: J. Reprod. Med., 34, 588 (1989); Del Palacio-Hernanz, A., et. al.: Chemioterapia, 3, 192 (1984); Van Cutsem, J., et. al.: Chemotherapy, 29, 322 (1983);

Formula: C₂₆H₃₁Cl₂N₅O₃

Colore e forma: Neat

Peso molecolare: 532.46

Ref: TR-T110600

Terconazole-d8

Prodotto controllato

CAS: 67915-31-5

Formula: C₂₆D₈H₂₃Cl₂N₅O₃

Colore e forma: Neat

Peso molecolare: 540.511

Ref: TR-T110602