CAS 6990-06-3

Acido fusidico

Descrizione:

Acido fusidico è un antibiotico steroideo derivato principalmente dal fungo Fusidium coccineum. È caratterizzato dalla sua capacità di inibire la sintesi proteica batterica, rendendolo efficace contro una gamma di batteri Gram-positivi, inclusa Staphylococcus aureus. Acido fusidico è spesso utilizzato in formulazioni topiche per trattare infezioni cutanee, in particolare quelle causate da ceppi resistenti. Il composto è noto per la sua bassa solubilità in acqua, che influisce sulla sua formulazione e sui metodi di somministrazione. Ha un profilo di tossicità relativamente basso, ma il suo uso può portare a resistenza se non somministrato correttamente. Acido fusidico è tipicamente disponibile in varie forme, tra cui creme, unguenti e colliri, e a volte è combinato con altri antibiotici per aumentarne l'efficacia. Il suo meccanismo d'azione implica il legame con il fattore di allungamento G (EF-G) nei batteri, impedendo così il passaggio di traslocazione durante la sintesi proteica. In generale, Acido fusidico è un agente prezioso nel trattamento di infezioni localizzate, in particolare nelle applicazioni dermatologiche.

Formula: C₃₁H₄₈O₆

InChI: InChI=1/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20+/t18-,21-,22-,23+,24+,25-,27?,29-,30-,31-/m0/s1

InChI key: InChIKey=IECPWNUMDGFDKC-MZJAQBGESA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H]

Sinonimi:

• (2E)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17E)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• 16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-
• Acide Fusidique
• Acido Fusidico
• Flucidin
• Foban
• Fucithalmic
• Fugen
• Fusidate Acid
• Fusidic Acid
• Fusidine
• Fusidinic acid
• Fusidinsaure
• Nsc 56192
• Optifucin
• Phudicin
• Ramycin
• Sq 16603
• Usidin
• (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-Nordammara-17(20),24-dien-21-oic acid
• 4-alpha,8-alpha,9-beta,11-alpha,13-alpha,14-beta,16-beta,17z)-ph
• FUSIDIC ACID IP
• (4S,8α,9β,13α,14β,17Z)-16β-Acetoxy-3α,11α-dihydroxy-29-nor-5α-dammara-17(20),24-dien-21-oic acid
• (8α,9β,13α,14β,Z)-16β-Acetyloxy-3α,11α-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• sq16603
• (3ALPHA,4ALPHA,8ALPHA,9BETA,11ALPHA,13ALPHA,14BETA,16BETA,17Z)-16-(ACETYLOXY)-3,11-DIHYDROXY-29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID
• (3a,4a,8a,9,11a,13a,147,167,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid
• 24-dien-21-oicacid,16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20(3-al
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3.alpha.,4.alpha.,8.alpha.,9.beta.,11.alpha.,13.alpha.,14.beta.,16.beta.,17Z)-

Fusidic acid; Fucidin; Ramycin; NSC 56192; NSC-5619-2; SQ 16603; ZN-6; Fusidinic acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Purezza: 85.66%

Colore e forma: Brownish oily solid

Peso molecolare: 516.0

Ref: 8R-AD0023

FUSIDIC ACID CRS

CAS: 6990-06-3

FUSIDIC ACID CRS

Formula: C₃₁H₄₈O₆

Colore e forma: Added Modified

Peso molecolare: 516.7092

Ref: 41-Y0001411

FUSIDIC ACID FOR PEAK IDENTIFICATION CRS

CAS: 6990-06-3

FUSIDIC ACID FOR PEAK IDENTIFICATION CRS

Formula: C₃₁H₄₈O₆

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 516.7092

Ref: 41-Y0001394

(3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 516.7092

Ref: IN-DA003ACO

Fusidic acid

CAS: 6990-06-3

Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.

Formula: C₃₁H₄₈O₆

Purezza: 98.68% - 99.53%

Colore e forma: Solid

Peso molecolare: 516.71

Ref: TM-T1160

Fusidic acid

CAS: 6990-06-3

Fusidic acid

Purezza: ≥98%

Peso molecolare: 516.71g/mol

Ref: 54-BUP16640

Fusidic acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆·xH₂O

Purezza: 98.0 - 101.0 % (dried basis)

Colore e forma: White or almost white crystalline powder

Peso molecolare: 516.71 (anhydrous)

Ref: 7W-GA1848

Fusidic Acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Colore e forma: White To Off-White Solid

Peso molecolare: 516.72

Ref: 4Z-F-281

Fusidic Acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 516.72

Ref: 3B-F1007

Fusidic acid

Prodotto controllato

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Colore e forma: Neat

Peso molecolare: 516.71

Ref: 04-C13989500

Fusidic acid, free acid

CAS: 6990-06-3

Fusidic acid, free acid

Formula: C₃₁H₄₈O₆

Purezza: 97%

Colore e forma: white solid

Peso molecolare: 516.71g/mol

Ref: 54-BIF6400

Fusidic Acid-d6

Prodotto controllato

CAS: 6990-06-3

Applications Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999), Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999), Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999),

Formula: C₃₁H₄₂D₆O₆

Colore e forma: Neat

Peso molecolare: 522.71

Ref: TR-F865502

Fusidic Acid

CAS: 6990-06-3

Stability Hygroscopic
Applications Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Dyes and metabolites.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999), Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999), Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999),

Formula: C₃₁H₄₈O₆

Colore e forma: White

Peso molecolare: 516.71

Ref: TR-F865500

FUSIDIC ACID

CAS: 6990-06-3

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 516.718994140625

Ref: 10-F794556

Fusidic acid

CAS: 6990-06-3

Inhibitor of protein synthesis; steroid antibiotic

Formula: C₃₁H₄₈O₆

Purezza: Min. 95 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 516.71 g/mol

Ref: 3D-AF23629