CAS 6990-06-3

Acido fusidico

Descrizione:

Acido fusidico è un antibiotico steroideo derivato principalmente dal fungo Fusidium coccineum. È caratterizzato dalla sua capacità di inibire la sintesi proteica batterica, rendendolo efficace contro una gamma di batteri Gram-positivi, inclusa Staphylococcus aureus. Acido fusidico è spesso utilizzato in formulazioni topiche per trattare infezioni cutanee, in particolare quelle causate da ceppi resistenti. Il composto è noto per la sua bassa solubilità in acqua, che influisce sulla sua formulazione e sui metodi di somministrazione. Ha un profilo di tossicità relativamente basso, ma il suo uso può portare a resistenza se non somministrato correttamente. Acido fusidico è tipicamente disponibile in varie forme, tra cui creme, unguenti e colliri, e a volte è combinato con altri antibiotici per aumentarne l'efficacia. Il suo meccanismo d'azione implica il legame con il fattore di allungamento G (EF-G) nei batteri, impedendo così il passaggio di traslocazione durante la sintesi proteica. In generale, Acido fusidico è un agente prezioso nel trattamento di infezioni localizzate, in particolare nelle applicazioni dermatologiche.

Formula: C₃₁H₄₈O₆

InChI: InChI=1/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20+/t18-,21-,22-,23+,24+,25-,27?,29-,30-,31-/m0/s1

InChI key: InChIKey=IECPWNUMDGFDKC-MZJAQBGESA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H]

Sinonimi:

• (2E)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17E)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• 16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-
• Acide Fusidique
• Acido Fusidico
• Flucidin
• Foban
• Fucithalmic
• Fugen
• Fusidate Acid
• Fusidic Acid
• Fusidine
• Fusidinic acid
• Fusidinsaure
• Nsc 56192
• Optifucin
• Phudicin
• Ramycin
• Sq 16603
• Usidin
• (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-Nordammara-17(20),24-dien-21-oic acid
• 4-alpha,8-alpha,9-beta,11-alpha,13-alpha,14-beta,16-beta,17z)-ph
• FUSIDIC ACID IP
• (4S,8α,9β,13α,14β,17Z)-16β-Acetoxy-3α,11α-dihydroxy-29-nor-5α-dammara-17(20),24-dien-21-oic acid
• (8α,9β,13α,14β,Z)-16β-Acetyloxy-3α,11α-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
• sq16603
• (3ALPHA,4ALPHA,8ALPHA,9BETA,11ALPHA,13ALPHA,14BETA,16BETA,17Z)-16-(ACETYLOXY)-3,11-DIHYDROXY-29-NORDAMMARA-17(20),24-DIEN-21-OIC ACID
• (3a,4a,8a,9,11a,13a,147,167,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid
• 24-dien-21-oicacid,16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20(3-al
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3.alpha.,4.alpha.,8.alpha.,9.beta.,11.alpha.,13.alpha.,14.beta.,16.beta.,17Z)-

Fusidic acid; Fucidin; Ramycin; NSC 56192; NSC-5619-2; SQ 16603; ZN-6; Fusidinic acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Purezza: 85.66%

Colore e forma: Brownish oily solid

Peso molecolare: 516.0

Ref: 8R-AD0023

FUSIDIC ACID CRS

CAS: 6990-06-3

FUSIDIC ACID CRS

Formula: C₃₁H₄₈O₆

Colore e forma: Added Modified

Peso molecolare: 516.7092

Ref: 41-Y0001411

FUSIDIC ACID FOR PEAK IDENTIFICATION CRS

CAS: 6990-06-3

FUSIDIC ACID FOR PEAK IDENTIFICATION CRS

Formula: C₃₁H₄₈O₆

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 516.7092

Ref: 41-Y0001394

Fusidic acid

CAS: 6990-06-3

Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.

Formula: C₃₁H₄₈O₆

Purezza: 98.68% - 99.53%

Colore e forma: White Solid

Peso molecolare: 516.71

Ref: TM-T1160

Fusidic acid

CAS: 6990-06-3

Fusidic acid

Formula: C₃₁H₄₈O₆

Purezza: ≥98%

Peso molecolare: 516.71

Ref: 54-BUP16640

(3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 516.7092

Ref: IN-DA003ACO

Fusidic Acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Colore e forma: White To Off-White Solid

Peso molecolare: 516.72

Ref: 4Z-F-281

Fusidic acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆·xH₂O

Purezza: 98.0 - 101.0 % (dried basis)

Colore e forma: White or almost white crystalline powder

Peso molecolare: 516.71 (anhydrous)

Ref: 7W-GA1848

Fusidic Acid (Standard)

CAS: 6990-06-3

Fusidic Acid (Standard) is the standard substance of Fusidic Acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.

Formula: C₃₁H₄₈O₆

Peso molecolare: 516.71

Ref: TM-TMSM-1248

Fusidic acid

Prodotto controllato

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Colore e forma: Neat

Peso molecolare: 516.71

Ref: 04-C13989500

Fusidic Acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 516.72

Ref: 3B-F1007

Fusidic acid, free acid

CAS: 6990-06-3

Fusidic acid, free acid

Formula: C₃₁H₄₈O₆

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 516.70921

Ref: 54-BIF6400

Fusidic Acid

CAS: 6990-06-3

Formula: C₃₁H₄₈O₆

Peso molecolare: 516.72

Ref: ST-EA-CP-F45016

Fusidic Acid-d6

Prodotto controllato

CAS: 6990-06-3

Applications Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999), Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999), Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999),

Formula: C₃₁H₄₂D₆O₆

Colore e forma: Neat

Peso molecolare: 522.71

Ref: TR-F865502

FUSIDIC ACID

CAS: 6990-06-3

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 516.718994140625

Ref: 10-F794556

Fusidic Acid

CAS: 6990-06-3

Stability Hygroscopic
Applications Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA. Dyes and metabolites.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999), Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999), Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999),

Formula: C₃₁H₄₈O₆

Colore e forma: Neat

Peso molecolare: 516.71

Ref: TR-F865500

Fusidic acid

CAS: 6990-06-3

Inhibitor of protein synthesis; steroid antibiotic

Formula: C₃₁H₄₈O₆

Purezza: Min. 95 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 516.71 g/mol

Ref: 3D-AF23629

Fusidine

CAS: 6990-06-3

(Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-3,11-dihydroxy-4,8,10,14-tetramethyldodecahydro-1H-cyclopenta[a]phenanthren-17(2H,10H,14H)-ylidene)-6-methylhept-5-enoic acid

Formula: C₃₁H₄₈O₆

Purezza: 97%

Peso molecolare: 516.71

Ref: IN-DG105687