CAS 71-27-2

Cloruro di succinilcolina

Descrizione:

Cloruro di succinilcolina è un bloccante neuromuscolare sintetico e depolarizzante comunemente usato in contesti medici, in particolare per facilitare l'intubazione e fornire rilassamento muscolare durante le procedure chirurgiche. È un composto di ammonio quaternario derivato dalla combinazione di due molecole di acetilcolina, che porta alla sua azione sulla giunzione neuromuscolare. La sostanza è caratterizzata da un rapido inizio e una breve durata d'azione, che di solito dura solo pochi minuti, rendendola ideale per interventi chirurgici brevi. La succinilcolina agisce legandosi ai recettori nicotinici dell'acetilcolina nella placca terminale motoria, causando una contrazione muscolare iniziale seguita da paralisi a causa della depolarizzazione sostenuta. È importante notare che il suo uso può essere associato a effetti collaterali, tra cui iperkaliemia, ipertermia maligna e bradicardia. A causa delle sue proprietà farmacologiche, la succinilcolina è classificata come sostanza controllata di Classe IV in alcune giurisdizioni, e la sua somministrazione deve essere attentamente monitorata dai professionisti sanitari.

Formula: C₁₄H₃₀N₂O₄·2Cl

InChI: InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

InChI key: InChIKey=YOEWQQVKRJEPAE-UHFFFAOYSA-L

SMILES: C([N+](C)(C)C)COC(CCC(OCC[N+](C)(C)C)=O)=O.[Cl-]

Sinonimi:

• (2-Hydroxyethyl)trimethylammonium chloride succinate
• 2,2-Succinyldioxybis(Ethyltrimethylammonium) Dichloride
• 2-Dimethylaminoethyl succinate dimethochloride
• Anectine
• Anectine chloride
• Bis(2-dimethylaminoethyl) succinate bis(methochloride)
• Choline succinate dichloride
• Choline, chloride, succinate (2:1)
• Choline,chloride succinate
• Diacetylcholine dichloride
• Ethanaminium, 2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, chloride (1:2)
• Ethanaminium, 2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, dichloride
• Lysthenon
• Lysthenone
• Midarine
• Myoplegine
• Pantolax
• Quelicin
• Quelicin chloride
• Querlicin
• Scoline
• Scoline chloride
• Skolin
• Succicuran
• Succin
• Succinic acid bis[β-dimethylaminoethyl] ester dimethochloride
• Succinic acid, diester with choline chloride
• Succinolin
• Succinoylcholine chloride
• Succinyl bischoline chloride
• Succinyl-asta
• Succinylbischoline dichloride
• Succinylcholine chloride
• Succinylcholine dichloride
• Succinyldicholine chloride
• Succinylforte
• Sucostrin
• Sucostrin chloride
• Sukolin

Ethanaminium, 2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, chloride (1:2)

CAS: 71-27-2

Ethanaminium, 2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, chloride (1:2)

Formula: C₁₄H₃₀ClN₂O₄

Purezza: 98%

Peso molecolare: 325.85

Ref: 54-OR1138735

Succinylcholine Chloride

Prodotto controllato

CAS: 71-27-2

Stability Hygroscopic
Applications A neuromuscular blocking agent. Muscle relaxant (skeletal).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jensen, B., et al.: Acta Chem. Scand., 30, 1002 (1976), Anttila, P., et al.: Med. Biol., 56, 152 (1978), Foss, P.R.B., et al.: Anal. Profiles Drug Subs., 10, 691 (1981),

Formula: C₁₄H₃₀N₂O₄·2Cl

Colore e forma: Neat

Peso molecolare: 361.3

Ref: TR-S692100

Succinylcholine Chloride

CAS: 71-27-2

Formula: C₁₄H₃₀N₂O₄·2Cl

Peso molecolare: 290.40 2 35.45

Ref: 4Z-C-5916

Succinylcholine chloride

CAS: 71-27-2

Succinylcholine chloride is a muscle relaxant that has been used to treat herpes simplex virus, congenital heart disease, and other conditions. Succinylcholine chloride is an ester of succinic acid and choline. It binds to the acetylcholine receptor on the postsynaptic membrane of skeletal muscles, which leads to depolarization and contraction. The binding of succinylcholine to its receptor triggers an influx of sodium ions into the cell, which causes membrane depolarization and muscle relaxation. Succinylcholine chloride has been shown to have neurotrophic effects in a study where it was administered to mice with experimental myocardial infarction. This drug also has been shown to increase microvessel density in pigs with intubation.

Formula: C₁₄H₃₀Cl₂N₂O₄

Purezza: (Hplc) Min. 96%

Colore e forma: Powder

Peso molecolare: 361.3 g/mol

Ref: 3D-FS27921

Succinylcholine Chloride-13C6

Prodotto controllato

CAS: 71-27-2

Applications A neuromuscular blocking agent. Muscle relaxant (skeletal).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jensen, B., et al.: Acta Chem. Scand., 30, 1002 (1976), Anttila, P., et al.: Med. Biol., 56, 152 (1978), Foss, P.R.B., et al.: Anal. Profiles Drug Subs., 10, 691 (1981),

Formula: C₆C₈H₃₀N₂O₄·2Cl

Colore e forma: Neat

Peso molecolare: 367.261

Ref: TR-S692102

Succinylcholine Chloride

CAS: 71-27-2

Formula: C₁₄H₃₀N₂O₄(Cl)

Peso molecolare: 290.4 : 2(35.45)

Ref: ST-EA-CP-S101002