CAS 7177-50-6
:Nafcillina sodica monoidrato
Descrizione:
Nafcillina sodica monoidrato è un antibiotico penicillina semisintetico, utilizzato principalmente per trattare infezioni causate da stafilococchi produttori di penicilinasi. È caratterizzato dalla sua capacità di resistere alla degradazione da parte di alcune beta-lattamasi, rendendolo efficace contro ceppi batterici specifici. Il composto appare come una polvere cristallina bianca a bianco sporco ed è solubile in acqua, il che facilita la sua somministrazione per iniezione. La sua struttura molecolare include un anello beta-lattamico, un anello di tiazolidina e un ione sodio, contribuendo alle sue proprietà antibatteriche. Nafcillina sodica monoidrato viene tipicamente somministrato per via endovenosa o intramuscolare, e la sua farmacocinetica comporta una rapida distribuzione nei tessuti corporei, con una emivita relativamente breve. Gli effetti collaterali comuni possono includere reazioni allergiche, disturbi gastrointestinali e potenziale nefrotossicità. Come con altri antibiotici, è essenziale utilizzare Nafcillina sodica monoidrato in modo giudizioso per prevenire lo sviluppo di resistenza agli antibiotici. Nel complesso, rimane un'opzione critica nel trattamento di alcune infezioni batteriche, in particolare quelle causate da ceppi resistenti.
Formula:C21H23N2NaO6S
InChI:InChI=1/C21H22N2O5S.Na.H2O/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);;1H2/q;+1;/p-1/t15-,16+,19-;;/m1../s1
InChI key:InChIKey=RKBDQTFFBRQMPN-KMFBOIRUSA-N
SMILES:C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(=O)C=3C4=C(C=CC3OCC)C=CC=C4)C2=O)(SC1(C)C)[H].[Na].O
Sinonimi:- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S-(2alpha,5alpha,6beta))
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S,5R,6R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, [2S-(2α,5α,6β)]-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt, hydrate (1:1:1), (2S,5R,6R)-
- Monosodium (2S,5R,6R)-6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate monohydrate
- Nafcil
- Nafcillin natrium-1-wasser
- Nafcillin sodium salt monohydrate
- Sodium 6-(2-ethoxy-1-naphthamido)penicillanate monohydrate
- Sodium nafcillin monohydrate
- Unii-49G3001Bck
- Wy 3277
- sodium (2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
- Nafcillin monohydrate sodium salt
- NAFCILLINSODIUMSTERILE
- Sodium (2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
- nafcillin sodium
- Vedi altri sinonimi
Ordinare per
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Trovati 10 prodotti.
Nafcillin Sodium
CAS:Penicillins and their derivatives with a penicillanic acid structure and salts thereof, nesoiFormula:C21H21N2NaO5S·H2OColore e forma:White Light Yellow Crystalline PowderPeso molecolare:454.11745Nafcillin sodium monohydrate
CAS:Nafcillin sodium monohydrate (CL 8491) is a semi-synthetic naphthalene, nafcillin inhibits bacterial wall synthesis by a mechanism similar to penicillin.Formula:C21H21N2O5SNa·H2OPurezza:96.62%Colore e forma:White PowderPeso molecolare:454.47(2S,5R,6R)-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium hydrate
CAS:Formula:C21H23N2NaO6SPurezza:98%Colore e forma:SolidPeso molecolare:454.4719Nafcillin sodium monohydrate
CAS:Nafcillin sodium monohydrateFormula:C21H21N2O5SNa·H2OPurezza:≥90%Colore e forma:SolidPeso molecolare:454.47Nafcillin sodium salt monohydrate
CAS:Nafcillin sodium salt monohydratePurezza:98%(Contain 2-3% ethyl acetate)Peso molecolare:454.47g/molNafcillin sodium monohydrate 100 µg/mL in Acetonitrile
CAS:Formula:C21H21N2O5S·Na·H2OColore e forma:Single SolutionPeso molecolare:454.47Nafcillin sodium salt monohydrate
CAS:Formula:C21H21N2O5SNa·H2OPurezza:≥ 98.5% (anhydrous basis)Colore e forma:White to yellow crystalline powder or crystalsPeso molecolare:454.47Sodium Nafcillin Monohydrate
CAS:Applications Sodium Nafcillin Monohydrate is used as an antibiotic, used in the treatment, used in the treatment of gram-positive bacteria.
References Taboada, P. et al.: Langmuir. 16, 3175 (2000);Formula:C21H21N2O5S·Na·H2OColore e forma:NeatPeso molecolare:454.47Nafcilllin sodium monohydrate
CAS:Nafcillin sodium monohydrate is a beta-lactam antibiotic, which is derived from the penicillin class of antimicrobials. It is specifically a semi-synthetic penicillin and is commonly sourced through chemical synthesis to enhance its stability and spectrum of activity. Nafcillin primarily exerts its bactericidal effects by inhibiting bacterial cell wall synthesis. It achieves this through its strong affinity for penicillin-binding proteins (PBPs), which are essential for maintaining the bacterial cell wall structure. By disrupting the formation of peptidoglycan cross-links, nafcillin effectively weakens the bacterial cell wall, leading to cell lysis and death, especially in gram-positive bacteria such as Staphylococcus aureus, including methicillin-sensitive strains (MSSA).Formula:C21H21N2O5SNa·H2OPurezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:454.47 g/molRef: ST-EA-CP-N68001
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![(2S,5R,6R)-6-[[(2-Ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2…](https://static.cymitquimica.com/products/IN/thumb/DA0062G3.jpg)
