CAS 72957-38-1

frammento di dinorfina A 1-13

Descrizione:

frammento di dinorfina A 1-13 è un peptide derivato dalla molecola più grande dinorfina A, che fa parte della famiglia dei peptidi oppioidi endogeni. Questo frammento è composto da 13 aminoacidi ed è noto per il suo ruolo nella modulazione del dolore, delle risposte allo stress e di vari processi neurofisiologici. Interagisce principalmente con i recettori kappa-opioidi nel sistema nervoso centrale, contribuendo ai suoi effetti analgesici. Il peptide presenta caratteristiche tipiche dei peptidi oppioidi, inclusa la capacità di indurre analgesia e influenzare l'umore e le risposte emotive. La sua struttura include sequenze specifiche che sono cruciali per il legame e l'attività del recettore. Inoltre, frammento di dinorfina A 1-13 può avere implicazioni in varie condizioni neurologiche ed è di interesse nella ricerca relativa alla dipendenza, alla depressione e ad altri disturbi dell'umore. Come peptide sintetico o di origine naturale, può essere studiato per le sue proprietà farmacologiche e potenziali applicazioni terapeutiche.

Formula: C₇₅H₁₂₆N₂₄O₁₅

InChI: InChI=1/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54?,55-,56-,57-,58-,61-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCCN)C(=N[C@@H](CC(C)C)C(=NC(CCCCN)C(=O)O)O)O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O

Sinonimi:

• Dynorphin A (1-13)
• H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
• Dynorphin A 1-13, Porcine

Dynorphin A (1-13)

CAS: 72957-38-1

Endogenous kappa-opioid receptor agonist. It is suggested that it attenuates galanin-induced impairment of memory processes through the mediation of kappa-opioid receptors.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 91.6%

Colore e forma: White Powder

Peso molecolare: 1603.98

Ref: 01-4004062

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH

CAS: 72957-38-1

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 98%

Peso molecolare: 1603.9547

Ref: IN-DA01E9V2

Dynorphin A (1-13) Acetatexa0

CAS: 72957-38-1

Ref: 7W-GX0937

Dynorphin A(1-13) Acetate

CAS: 72957-38-1

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 95%~99%

Colore e forma: White to Off-white Powder

Peso molecolare: 1603.97

Ref: BP-BPPG022

Porcine dynorphin A(1-13)

CAS: 72957-38-1

Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1603.95

Ref: TM-TP1179

Porcine Dynorphin A(1-13)

CAS: 72957-38-1

Porcine Dynorphin A(1-13)

Purezza: 99%

Peso molecolare: 1,603.95g/mol

Ref: 54-BISN0009

Dynorphin A (1-13)

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₇₅H₁₂₆N₂₄O₁₅

Peso molecolare: 1,603.95 g/mol

Ref: 3D-PP50465

Dynorphin A (1-12), porcine

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₆₉H₁₁₄N₂₂O₁₄

Peso molecolare: 1,475.82 g/mol

Ref: 3D-PP50361

Dynorphin A (Human, 1-13)

CAS: 72957-38-1

As a dynorphin peptide, Dynorphin A has affinity for opioid receptors in particular it favors kappa-opioid receptors and residues 1-13 of the Dynorphin A peptide are crucial for its potency. Kappa-opioid receptors are expressed in the brain, peripheral tissues and the spinal cord and are located in areas involved in pain. For example when Dynorphin A binds to kappa-opioid receptors, dopamine is inhibited in areas of the brain prevalent in drug addiction, thus demonstrated Dynorphin A to have antagonistic effects on the brain reward circuit. Dynorphin A could be a useful research tool for studying analgesia, reward and addiction.
This product is available as a 0.5mg vial.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: Min. 95%

Peso molecolare: 1,604 g/mol

Ref: 3D-PDY-4080-V

Dynorphin A (porcine 1-13) - acetate salt

CAS: 72957-38-1

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys is a peptide that is found in the brain and spinal cord. It is an agonist of opioid receptors, which are involved in pain relief, as well as motor control. Dynorphin A (1-13) H has been shown to inhibit acetylcholine release, which may be due to its ability to bind to kappa opioid receptors. Dynorphin A (1-13) H is also known to bind to κ opioid receptors, where it inhibits locomotor activity and induces analgesia.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,603.96 g/mol

Ref: 3D-FD108725

Dynorphin A (1-13), Porcine

CAS: 72957-38-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Colore e forma: Lyophilized powder

Ref: 02-J64015