CAS 72957-38-1

frammento di dinorfina A 1-13

Descrizione:

frammento di dinorfina A 1-13 è un peptide derivato dalla molecola più grande dinorfina A, che fa parte della famiglia dei peptidi oppioidi endogeni. Questo frammento è composto da 13 aminoacidi ed è noto per il suo ruolo nella modulazione del dolore, delle risposte allo stress e di vari processi neurofisiologici. Interagisce principalmente con i recettori kappa-opioidi nel sistema nervoso centrale, contribuendo ai suoi effetti analgesici. Il peptide presenta caratteristiche tipiche dei peptidi oppioidi, inclusa la capacità di indurre analgesia e influenzare l'umore e le risposte emotive. La sua struttura include sequenze specifiche che sono cruciali per il legame e l'attività del recettore. Inoltre, frammento di dinorfina A 1-13 può avere implicazioni in varie condizioni neurologiche ed è di interesse nella ricerca relativa alla dipendenza, alla depressione e ad altri disturbi dell'umore. Come peptide sintetico o di origine naturale, può essere studiato per le sue proprietà farmacologiche e potenziali applicazioni terapeutiche.

Formula: C₇₅H₁₂₆N₂₄O₁₅

InChI: InChI=1/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54?,55-,56-,57-,58-,61-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCCN)C(=N[C@@H](CC(C)C)C(=NC(CCCCN)C(=O)O)O)O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O

Sinonimi:

• Dynorphin A (1-13)
• H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
• Dynorphin A 1-13, Porcine

Porcine Dynorphin A(1-13)

CAS: 72957-38-1

Porcine Dynorphin A(1-13)

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 99%

Peso molecolare: 1603.95473

Ref: 54-BISN0009

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH

CAS: 72957-38-1

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 98%

Peso molecolare: 1603.9547

Ref: IN-DA01E9V2

Dynorphin A (1-13) Acetatexa0

CAS: 72957-38-1

Ref: 7W-GX0937

Dynorphin A(1-13) Acetate

CAS: 72957-38-1

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 95%~99%

Colore e forma: White to Off-white Powder

Peso molecolare: 1603.97

Ref: BP-BPPG022

Porcine dynorphin A(1-13)

CAS: 72957-38-1

Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1603.95

Ref: TM-TP1179

Dynorphin A (Human, 1-13)

CAS: 72957-38-1

As a dynorphin peptide, Dynorphin A has affinity for opioid receptors in particular it favors kappa-opioid receptors and residues 1-13 of the Dynorphin A peptide are crucial for its potency. Kappa-opioid receptors are expressed in the brain, peripheral tissues and the spinal cord and are located in areas involved in pain. For example when Dynorphin A binds to kappa-opioid receptors, dopamine is inhibited in areas of the brain prevalent in drug addiction, thus demonstrated Dynorphin A to have antagonistic effects on the brain reward circuit. Dynorphin A could be a useful research tool for studying analgesia, reward and addiction.
This product is available as a 0.5mg vial.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: Min. 95%

Peso molecolare: 1,604 g/mol

Ref: 3D-PDY-4080-V

Dynorphin A (porcine 1-13) - acetate salt

CAS: 72957-38-1

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys is a peptide that is found in the brain and spinal cord. It is an agonist of opioid receptors, which are involved in pain relief, as well as motor control. Dynorphin A (1-13) H has been shown to inhibit acetylcholine release, which may be due to its ability to bind to kappa opioid receptors. Dynorphin A (1-13) H is also known to bind to κ opioid receptors, where it inhibits locomotor activity and induces analgesia.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,603.96 g/mol

Ref: 3D-FD108725

Dynorphin A (1-13)

CAS: 72957-38-1

Endogenous kappa-opioid receptor agonist. It is suggested that it attenuates galanin-induced impairment of memory processes through the mediation of kappa-opioid receptors.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purezza: 91.6%

Colore e forma: White Powder

Peso molecolare: 1603.98

Ref: 01-4004062