CAS 73231-34-2

Florfenicol

Descrizione:

Florfenicol è un antibiotico sintetico appartenente alla classe dei fenicoli, utilizzato principalmente in medicina veterinaria per il trattamento delle infezioni batteriche negli animali. È efficace contro un ampio spettro di batteri Gram-positivi e Gram-negativi, rendendolo un agente terapeutico prezioso. Florfenicol agisce inibendo la sintesi proteica batterica, mirando specificamente alla subunità ribosomiale 50S, il che interrompe la produzione di proteine essenziali necessarie per la crescita e la riproduzione batterica. La sostanza è caratterizzata dalla sua tossicità relativamente bassa negli animali rispetto ad altri antibiotici, il che consente il suo utilizzo negli animali da produzione alimentare in condizioni regolate. Florfenicol viene tipicamente somministrato per iniezione o in formulazioni alimentari, e la sua farmacocinetica indica una buona penetrazione nei tessuti, il che è vantaggioso per il trattamento delle infezioni sistemiche. Tuttavia, il suo utilizzo è soggetto a rigorose regolamentazioni a causa di preoccupazioni riguardanti la resistenza agli antibiotici e i potenziali residui nei prodotti alimentari. In generale, Florfenicol rappresenta uno strumento importante nella medicina veterinaria, bilanciando l'efficacia contro le infezioni batteriche con considerazioni di sicurezza e conformità normativa.

Formula: C₁₂H₁₄Cl₂FNO₄S

InChI: InChI=1/C12H14Cl2FNO2S/c1-19-8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)

InChI key: InChIKey=AYIRNRDRBQJXIF-NXEZZACHSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CF)(O)C1=CC=C(S(C)(=O)=O)C=C1

Sinonimi:

• 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
• 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
• 2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
• Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
• Acetamide, 2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,S*)]-
• Aquafen
• Aquaflor
• Flofenicol
• Flonicol
• Florfeniol
• Florgane
• Floron
• Nuflor
• Sch 25298
• Selectan
• Topazone
• Florfenicol
• [R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
• Fluorothiamphenicol
• [r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
• Sch-25298, Aquafen
• (r-(r*,s*))-methyleste
• 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
• 2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
• Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
• FLUPROFEN
• Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid

Florfenicol

CAS: 73231-34-2, 76639-94-6

Formula: C₁₂H₁₄Cl₂FNO₄S

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 358.21

Ref: 3B-F0811

Florfenicol, 98%

CAS: 73231-34-2

A bacteriostatic antibiotic similar to chloramphenicol which inhibits bacterial protein synthesis This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar pr

Formula: C₁₂H₁₄Cl₂FNO₄S

Purezza: 98%

Colore e forma: White to pale cream, Powder or crystalline powder

Peso molecolare: 358.21

Ref: 02-J66995

Acetamide, 2,​2-​dichloro-​N-​[(1S,​2R)​-​1-​(fluoromethyl)​-​2-​hydroxy-​2-​[4-​(methylsulfonyl)​phenyl]​ethyl]​-

CAS: 73231-34-2

Formula: C₁₂H₁₄Cl₂FNO₄S

Purezza: %

Colore e forma: Solid

Peso molecolare: 358.2133

Ref: IN-DA00ICDO

Florfenicol

CAS: 73231-34-2

Florfenicol treats bovine respiratory disease and foot rot in cattle, and catfish enteric septicemia.

Formula: C₁₂H₁₄Cl₂FNO₄S

Purezza: 99.22% - 99.33%

Colore e forma: White Crystalline Powder

Peso molecolare: 358.21

Ref: TM-T0454L

Florfenicol

CAS: 73231-34-2

Florfenicol

Purezza: 98%

Peso molecolare: 358.21g/mol

Ref: 54-PC109152

Florfenicol

CAS: 73231-34-2

Formula: C₁₂H₁₄Cl₂FNO₄S

Colore e forma: White To Off-White Solid

Peso molecolare: 358.22

Ref: 4Z-F-231

Florfenicol

CAS: 73231-34-2

Formula: C₁₂H₁₄Cl₂FNO₄S

Purezza: ≥ 98.0% (dried basis)

Colore e forma: White to off-white powder

Peso molecolare: 358.21

Ref: 7W-GA3827

Florfenicol

Prodotto controllato

CAS: 73231-34-2

Formula: C₁₂H₁₄Cl₂FNO₄S

Colore e forma: Neat

Peso molecolare: 358.21

Ref: 04-C13665000

Florfenicol-d5

CAS: 73231-34-2

Formula: C₁₂H₉D₅Cl₂FNO₄S

Colore e forma: White To Off-White Solid

Peso molecolare: 363.24

Ref: 4Z-F-2314

Florfenicol

CAS: 73231-34-2

Applications Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.
References Kim, E and Aoki, T.: Microbiol. Immunol., 40, 665, (1996), Keyes, K.: Antimicrob. Agents Chemother., 44, 421 (2000)

Formula: C₁₂H₁₄Cl₂FNO₄S

Colore e forma: Yellow

Peso molecolare: 358.21

Ref: TR-F405750

Florfenicol

CAS: 73231-34-2

Florfenicol is a broad-spectrum antibiotic that belongs to the group of florfenicol. It is used in veterinary medicine to treat bacterial infections in animals, including those caused by salmonella, streptococcus, and mycoplasma. Florfenicol has been shown to have an inhibitory effect on the growth of tetracycline-resistant bacteria. Florfenicol binds reversibly to the 23S ribosomal RNA in the 50S subunit of bacteria and inhibits protein synthesis. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme ribosome that is required for translation, inhibiting protein synthesis and cell division. The rate constant for this reaction has been determined using a combination of analytical methods, including chromatographic analysis and colloidal gold electrophoresis. Florfenicol also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.

Formula: C₁₂H₁₄Cl₂FNO₄S

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 358.21 g/mol

Ref: 3D-FF23306

Florfenicol - Bio-X ™

CAS: 73231-34-2

Florfenicol is a broad-spectrum antibiotic used for the treatment of various bacteria infections. This drug is used in veterinary medicine and to treat animals with those infections. This drug works by inhibiting bacteria synthesis. It is a fluorinated synthetic analog of thiamphenicol.

Formula: C₁₂H₁₄Cl₂FNO₄S

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 358.21 g/mol

Ref: 3D-BF166386

Florfenicol

CAS: 73231-34-2

Purezza: 99+%

Peso molecolare: 357

Ref: 10-F801753