CAS 73231-34-2
:Florfenicol
Descrizione:
Florfenicol è un antibiotico sintetico appartenente alla classe dei fenicoli, utilizzato principalmente in medicina veterinaria per il trattamento delle infezioni batteriche negli animali. È efficace contro un ampio spettro di batteri Gram-positivi e Gram-negativi, rendendolo un agente terapeutico prezioso. Florfenicol agisce inibendo la sintesi proteica batterica, mirando specificamente alla subunità ribosomiale 50S, il che interrompe la produzione di proteine essenziali necessarie per la crescita e la riproduzione batterica. La sostanza è caratterizzata dalla sua tossicità relativamente bassa negli animali rispetto ad altri antibiotici, il che consente il suo utilizzo negli animali da produzione alimentare in condizioni regolate. Florfenicol viene tipicamente somministrato per iniezione o in formulazioni alimentari, e la sua farmacocinetica indica una buona penetrazione nei tessuti, il che è vantaggioso per il trattamento delle infezioni sistemiche. Tuttavia, il suo utilizzo è soggetto a rigorose regolamentazioni a causa di preoccupazioni riguardanti la resistenza agli antibiotici e i potenziali residui nei prodotti alimentari. In generale, Florfenicol rappresenta uno strumento importante nella medicina veterinaria, bilanciando l'efficacia contro le infezioni batteriche con considerazioni di sicurezza e conformità normativa.
Formula:C12H14Cl2FNO4S
InChI:InChI=1/C12H14Cl2FNO2S/c1-19-8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)
InChI key:InChIKey=AYIRNRDRBQJXIF-NXEZZACHSA-N
SMILES:[C@@H]([C@H](NC(C(Cl)Cl)=O)CF)(O)C1=CC=C(S(C)(=O)=O)C=C1
Sinonimi:- 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
- 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
- 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
- 2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
- Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
- Acetamide, 2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,S*)]-
- Aquafen
- Aquaflor
- Flofenicol
- Flonicol
- Florfeniol
- Florgane
- Floron
- Nuflor
- Sch 25298
- Selectan
- Topazone
- Florfenicol
- [R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
- Fluorothiamphenicol
- [r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
- Sch-25298, Aquafen
- (r-(r*,s*))-methyleste
- 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
- 2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
- Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
- FLUPROFEN
- Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
- 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid
- Vedi altri sinonimi
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Florfenicol
CAS:Formula:C12H14Cl2FNO4SPurezza:>98.0%(HPLC)(N)Colore e forma:White to Light yellow powder to crystalPeso molecolare:358.21Florfenicol, 98%
CAS:A bacteriostatic antibiotic similar to chloramphenicol which inhibits bacterial protein synthesis This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar prFormula:C12H14Cl2FNO4SPurezza:98%Colore e forma:White to pale cream, Powder or crystalline powderPeso molecolare:358.21Florfenicol
CAS:Florfenicol treats bovine respiratory disease and foot rot in cattle, and catfish enteric septicemia.Formula:C12H14Cl2FNO4SPurezza:99.22% - 99.33%Colore e forma:White SolidPeso molecolare:358.21Florfenicol
CAS:FlorfenicolFormula:C12H14Cl2FNO4SPurezza:>98%Colore e forma:SolidPeso molecolare:358.21Florfenicol
CAS:Formula:C12H14Cl2FNO4SPurezza:≥ 98.0% (dried basis)Colore e forma:White to off-white powderPeso molecolare:358.21Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
CAS:Formula:C12H14Cl2FNO4SPurezza:98%Colore e forma:SolidPeso molecolare:358.2133Florfenicol
CAS:Applications Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.
References Kim, E and Aoki, T.: Microbiol. Immunol., 40, 665, (1996), Keyes, K.: Antimicrob. Agents Chemother., 44, 421 (2000)Formula:C12H14Cl2FNO4SColore e forma:NeatPeso molecolare:358.21Florfenicol-d5
CAS:Formula:C12H9D5Cl2FNO4SColore e forma:White To Off-White SolidPeso molecolare:363.24Ref: 4Z-F-2314
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaFlorfenicol
CAS:Florfenicol is a broad-spectrum antibiotic that belongs to the group of florfenicol. It is used in veterinary medicine to treat bacterial infections in animals, including those caused by salmonella, streptococcus, and mycoplasma. Florfenicol has been shown to have an inhibitory effect on the growth of tetracycline-resistant bacteria. Florfenicol binds reversibly to the 23S ribosomal RNA in the 50S subunit of bacteria and inhibits protein synthesis. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme ribosome that is required for translation, inhibiting protein synthesis and cell division. The rate constant for this reaction has been determined using a combination of analytical methods, including chromatographic analysis and colloidal gold electrophoresis. Florfenicol also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.Formula:C12H14Cl2FNO4SPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:358.21 g/molFlorfenicol - Bio-X ™
CAS:Florfenicol is a broad-spectrum antibiotic used for the treatment of various bacteria infections. This drug is used in veterinary medicine and to treat animals with those infections. This drug works by inhibiting bacteria synthesis. It is a fluorinated synthetic analog of thiamphenicol.Formula:C12H14Cl2FNO4SPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:358.21 g/molFlorfenicol-D4 (mixture of enantiomers) in Methanol
CAS:MethanolFormula:C12H14Cl2FNO4SPeso molecolare:358.2
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