CAS 751-03-1

Obacunone

Descrizione:

Obacunone è un composto naturale classificato come limonoide, derivato principalmente dai semi del frutto del genere Citrus, in particolare dalla specie Citrus Obacunone. È caratterizzato dalla sua complessa struttura tetraciclica, che include un sistema di anelli fusi che contribuisce alla sua attività biologica. Obacunone presenta una gamma di proprietà farmacologiche, tra cui effetti anti-infiammatori, anti-cancro e antimicrobici, rendendolo un argomento di interesse nella chimica medicinale e nella ricerca di prodotti naturali. Il composto si trova tipicamente in basse concentrazioni negli agrumi, e la sua estrazione e purificazione possono essere impegnative a causa della sua complessità strutturale. In termini di proprietà fisiche, Obacunone è generalmente un solido incolore o giallo pallido con un odore caratteristico. La sua solubilità varia, essendo più solubile nei solventi organici che in acqua. Lo studio di Obacunone continua a rivelare le sue potenziali applicazioni in prodotti farmaceutici e alimenti funzionali, evidenziando l'importanza dei composti naturali nella scoperta e nello sviluppo di farmaci.

Formula: C₂₆H₃₀O₇

InChI: InChI=1S/C26H30O7/c1-22(2)16-12-17(27)25(5)15(23(16,3)9-7-18(28)32-22)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)33-20/h7-9,11,13,15-16,19-20H,6,10,12H2,1-5H3/t15-,16+,19+,20-,23-,24+,25+,26-/m1/s1

InChI key: InChIKey=MAYJEFRPIKEYBL-OASIGRBWSA-N

SMILES: C[C@]12[C@]34[C@](O3)(C(=O)O[C@H]([C@]4(C)CC[C@@]1([C@]5(C)[C@@](CC2=O)(C(C)(C)OC(=O)C=C5)[H])[H])C=6C=COC6)[H]

Sinonimi:

• (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione
• (5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione
• (5aR,7aS,8R,10aS,11aR,11bR)-8-(furan-3-yl)-12,12-dihydroxy-1,1,5a,7a,11b-pentamethyl-5a,5b,6,7,7a,8,11b,12,13,13a-decahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10(1H,10aH)-dione
• 14,15:21,23-Diepoxy-4,4,8-trimethyl-A,<span class="text-smallcaps">D</span>-dihomo-24-nor-4,17-dioxachola-1,20,22-triene-3,7,16-trione
• Ai3-37934
• Ccris 8657
• Obacunoic acid 3,4-lactone
• Obacunoic acid, eta-lactone
• Obacunoic acid, ε-lactone
• Obacunon
• Obakunone
• Oxireno(4,4a)-2-benzopyrano(6,5-g)(2)benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aαH,4bH,6H)-trione, 1α-(3-furyl)-1,6aα,7,11a,11bα,12,13,13a-octahydro-4bβ,7,7,11aβ,13aα-pentamethyl-
• Tricoccin S₃
• [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 454.52

Ref: 3B-O0506

Obacunone

CAS: 751-03-1

Obacunone

Formula: C₂₆H₃₀O₇

Purezza: 98%

Peso molecolare: 454.51

Ref: 54-OR1023060

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Peso molecolare: 454.52

Ref: 7W-GY8065

Obacunone

CAS: 751-03-1

Obacunone

Formula: C₂₆H₃₀O₇

Purezza: 99.5%

Colore e forma: Solid

Peso molecolare: 454.51

Ref: 54-BUP10739

(1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 454.5122

Ref: IN-DA00G2A6

Obacunone (Standard)

CAS: 751-03-1

Obacunone (Standard) is a reference standard for research and analysis in studies involving Obacunone. Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.

Formula: C₂₆H₃₀O₇

Colore e forma: Solid

Peso molecolare: 454.5122

Ref: TM-TMSM-1938

Obacunone

CAS: 751-03-1

Obacunone is a novel activator of Nrf2, which exhibits anti-cancer, anti-inflammatory, antivirulence, insecticidal, anti-proliferative and anti-aromatase activities. Obacunone stimulates muscle hypertrophy and prevents obesity and hyperglycemia, and that these beneficial effects are likely to be mediated through the activation of TGR5 and inhibition of PPARγ transcriptional activity. Obacunone significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM, and it also inhibits the p38 MAPK signaling pathway.

Formula: C₂₆H₃₀O₇

Purezza: 95%~99%

Peso molecolare: 454.519

Ref: BP-BP1018

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Peso molecolare: 454.52

Ref: 4Z-O-086001

Obacunone

CAS: 751-03-1

Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.

Formula: C₂₆H₃₀O₇

Purezza: 98% - ≥95%

Colore e forma: White Powder

Peso molecolare: 454.5122

Ref: TM-T3390

Obacunone

CAS: 751-03-1

(1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione

Formula: C₂₆H₃₀O₇

Purezza: 98%

Peso molecolare: 454.51

Ref: IN-DG299914

Obacunone

CAS: 751-03-1

Lactone

Formula: C₂₆H₃₀O₇

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 454.52

Ref: 5G-80509

Obacunone

CAS: 751-03-1

Obacunone is a naturally occurring limonoid, which is a type of triterpenoid compound. It is derived from the peels of citrus plants, particularly bitter and sweet oranges. Obacunone operates through several mechanisms, including inducing apoptosis, inhibiting cell proliferation, and modulating various signaling pathways. Its biological activity has garnered attention for its potential therapeutic benefits.

Formula: C₂₆H₃₀O₇

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 454.51 g/mol

Ref: 3D-FO65314

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Peso molecolare: 454.5

Ref: BE-RMT12350

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Peso molecolare: 454.5

Ref: BE-RMCO001000

OBACUNONE

CAS: 751-03-1

Purezza: 98%

Peso molecolare: 454.5190125

Ref: 10-F795475

Obacunone

CAS: 751-03-1

Formula: C₂₆H₃₀O₇

Peso molecolare: 454.52

Ref: ST-EA-CP-O89000