CAS 80-92-2

Pregnandiolo

Descrizione:

Pregnandiolo è un composto steroideo che funge da metabolita significativo della progesterone, un ormone chiave nel sistema riproduttivo. È caratterizzato dalla sua struttura chimica, che include due gruppi idrossile (-OH), rendendolo un diolo. Pregnandiolo si trova tipicamente sotto forma di un liquido incolore o giallo pallido o solido, a seconda della sua purezza e delle condizioni. È solubile in solventi organici ma ha una solubilità limitata in acqua. Questo composto gioca un ruolo cruciale in vari processi biologici, in particolare nel metabolismo degli steroidi e nella regolazione delle funzioni riproduttive. In contesti clinici, i livelli di Pregnandiolo possono essere misurati per valutare la funzione ovarica e monitorare la gravidanza. Inoltre, è utilizzato nella ricerca per studiare le vie ormonali e gli effetti degli ormoni steroidei sul corpo. A causa della sua importanza biologica, comprendere le proprietà e il comportamento di Pregnandiolo è essenziale sia in farmacologia che in endocrinologia.

Formula: C₂₁H₃₆O₂

InChI: InChI=1/C21H36O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h13-19,22-23H,4-12H2,1-3H3/t13-,14-,15-,16-,17-,18-,19-,20+,21-/m0/s1

InChI key: InChIKey=YWYQTGBBEZQBGO-BERLURQNSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@H](C)O)(CC4)[H])[H])(CC[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Sinonimi:

• (3alpha,5beta,20S)-pregnane-3,20-diol
• (3alpha,5beta,20alpha)-Pregnane-3,20-diol
• (3α,5β,20S)-Pregnane-3,20-diol
• 17-(1-hydroxyethyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
• 3-alpha,20-alpha-Dihydroxy-5-beta-pregnane
• 3alpha,20alpha-Dihydroxy-5beta-pregnane
• 3α,20α-Dihydroxy-5β-pregnane
• 5-beta-Pregnane, 3-alpha,20-alpha-dihydroxy-
• 5-beta-Pregnane-3-alpha, 20-alpha-diol
• 5-Β-Pregnano-3-Α-20-Α-Diol
• 5-β-Pregnan-3-α,20-α-diol
• 5beta-Pregnane, 3alpha,20alpha-dihydroxy-
• 5beta-Pregnane-3alpha,20alpha-diol (8CI)
• 5β-Pregnane-3α,20α-diol
• Brn 3083715
• Diol
• Diol (6CI,7CI)
• Nsc 1612
• Nsc 47462
• Pregnandiol
• Pregnandiol [JAN]
• Pregnane-3,20-diol
• Pregnane-3,20-diol, (3-alpha,5-beta,20S)- (9CI)
• Pregnane-3,20-diol, (3alpha,5beta,20S)- (9CI)
• Pregnane-3,20-diol, (3α,5β,20S)-
• Pregnane-3alpha,20alpha-diol
• Pregnanediol
• Unii-Jr3Jd1Y22C
• 4-06-00-06111 (Beilstein Handbook Reference)
• 5SS-PREGNANE-3ALPHA,20ALPHA-DIOL
• 5-BETA-PREGNAN-3-ALPHA, 20-ALPHA-DIOL
• (8S,9S,10S,13R,14S,17S)-17-ethyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,3-diol
• Pregnane-3,20-diol, (3a,5b,20S)- (9CI)
• 3a,20a-Dihydroxy-5pregnane
• THA
• 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL
• (3α,5β),20S)-
• (3a,5),20S)-Pregnane-3,20-diol
• 5b-Pregnane-3a,20a-diol (8CI)
• 5-Pregnane-3alpha,20alpha-diol
• 3-alpha,20-alpha-dihydroxy-5-beta-pregnan
• 3ALPHA,20ALPHA-Dihydroxy-5B-pregnane
• (20S)-3α,20-Dihydroxy-5β-pregnane
• (20S)-5β-Pregnan-3α,20-diol
• Pregnane-3,20-diol, (3.alpha.,5.beta.,20S)-
• 5BETA-PREGNAN-3A,20A-DIOL
• 5β-Pregnane-3α,20α-diol-d5
• 5BETA-PREGNANE-3ALPHA 20ALPHA-DIOL 98+%
• TETRAHYDRO COMPOUND ''A''

5β-Pregnane-3α,20α-diol

CAS: 80-92-2

Formula: C₂₁H₃₆O₂

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 320.52

Ref: 3B-P0678

5β-Pregnane-3α,20α-diol

CAS: 80-92-2

Formula: C₂₁H₃₆O₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 320.5093

Ref: IN-DA003472

5β-Pregnane-3α,20α-diol

CAS: 80-92-2

5β-Pregnane-3α,20α-diol

Formula: C₂₁H₃₆O₂

Purezza: >95%

Peso molecolare: 320.52

Ref: 54-OR1023940

Pregnanediol

CAS: 80-92-2

Pregnanediol

Formula: C₂₁H₃₆O₂

Purezza: ≥98%

Peso molecolare: 320.51

Ref: 54-BUP11432

Pregnanediol

CAS: 80-92-2

Formula: C₂₁H₃₆O₂

Peso molecolare: 320.52

Ref: 4Z-P-462005

Pregnanediol (5β-Pregnane-3α,20(S)-diol)

CAS: 80-92-2

Colore e forma: Neat

Ref: 61-FOR0222.14

Pregnanediol (5β-Pregnane-3α,20(S)-diol)

Prodotto controllato

CAS: 80-92-2

Formula: C₂₁H₃₆O₂

Colore e forma: Neat

Peso molecolare: 320.51

Ref: 86-MM0222.14

Pregnanediol (5β-Pregnane-3α,20(S)-diol)

CAS: 80-92-2

Colore e forma: Neat

Ref: LP-PRO-2333

Pregnanediol

CAS: 80-92-2

Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of progesterone by reduction at C5, C3, and C20 position.

Formula: C₂₁H₃₆O₂

Purezza: 98% - 99.91%

Colore e forma: Solid

Peso molecolare: 320.51

Ref: TM-T1688

5-β-Pregnane-3-α,20-α-diol

CAS: 80-92-2

Applications 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900).
References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),

Formula: C₂₁H₃₆O₂

Colore e forma: Neat

Peso molecolare: 320.51

Ref: TR-P705130

5β-Pregnane-3α,20α-diol-d5

Prodotto controllato

CAS: 80-92-2

Applications Labelled 5β-Pregnane-3α,20α-diol, a metabolite of Progesterone (P755900).
References Beall, et al.: Biochem. J., 31, 35 (1937); Okuda, A. et al.: J. Biol. Chem., 259, 7519 (1984); Russell, D. et al.: Biochemistry, 31, 4737 (1992); Kondo, K. et al.: Eur. J. Biochem.; 219, 357 (1994); Westerbacka, J. et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003);

Formula: C₂₁H₃₁D₅O₂

Colore e forma: Neat

Peso molecolare: 325.54

Ref: TR-P705132

5β-Pregnane-3α,20α-diol

Prodotto controllato

CAS: 80-92-2

5β-Pregnane-3α,20α-diol is a human metabolite of estradiol that has been found to be an active inhibitor of the enzyme activity of GABA transaminase. It has been shown to have therapeutic potential in the prevention and treatment of cervical cancer, as well as other cancers. 5β-Pregnane-3α,20α-diol has also been found to inhibit ovarian activity. The diagnostic method for this metabolite is based on monoclonal antibody (MAb) reactivity with immunosorbent assay (ELISA) and gas chromatography/mass spectrometry (GC/MS). Women who have high values for this metabolite may be at risk for uterine cancer or breast cancer.

Formula: C₂₁H₃₆O₂

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 320.51 g/mol

Ref: 3D-FP27150