1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS 816-94-4

1,2-Distearoil-sn-glicero-3-fosfocolina

Descrizione:

1,2-Distearoil-sn-glicero-3-fosfocolina (DSPC) è un fosfolipide comunemente usato in biochimica e applicazioni farmaceutiche. È caratterizzato dalle sue due lunghe catene di acidi grassi saturi, in particolare acido stearico, che contribuiscono alle sue proprietà idrofobiche, e da un gruppo testa di fosfocolina che conferisce idrofobicità. Questa natura anfifilica consente al DSPC di formare doppi strati lipidici, rendendolo un componente cruciale nella formazione di liposomi e nanoparticelle lipidiche per sistemi di somministrazione di farmaci. Il DSPC ha un'alta temperatura di transizione di fase, che migliora la stabilità delle formulazioni lipidiche a temperature fisiologiche. È anche noto per la sua capacità di incapsulare composti idrofili e idrofobici, rendendolo versatile in varie applicazioni, tra cui la somministrazione di vaccini e la terapia genica. Inoltre, il DSPC è biocompatibile e biodegradabile, il che è essenziale per il suo utilizzo in formulazioni mediche e cosmetiche. La sua integrità strutturale e funzionalità lo rendono una sostanza preziosa nello sviluppo di nanocarrier e altri sistemi a base di lipidi in contesti di ricerca e clinici.

Formula:C₄₄H₈₈NO₈P

InChI:InChI=1/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key:InChIKey=NRJAVPSFFCBXDT-HUESYALOSA-N

SMILES:[C@H](OC(CCCCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCCCC)=O

Sinonimi:

(2R)-2,3-bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
(R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium 4-oxide
(R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium-4-oxid
1,2-L-α-Distearoylphosphatidylcholine
1,2-Bis(stearoyl)-sn-glycero-3-phosphocholine
1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine
1,2-Distearoyl-3-sn-phosphatidylcholine
1,2-Distearoyl-L-α-glycerophosphocholine
1,2-Distearoyl-L-α-glycerophosphocholine
1,2-Distearoyl-sn-3-phosphacholine
1,2-Distearoyl-sn-3-phosphocholine
1,2-Distearoyl-sn-glycero-3-phosphatidylcholine
1,2-Distearoyl-sn-glycero-3-phosphocholine
1,2-Distearoyl-sn-glycero-3-phosphorylcholine
1,2-Distearoyl-sn-glycerophosphocholine
1,2-L-α-Distearoylphosphatidylcholine
3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxooctadecyl)oxy)-, hydroxide, inner salt, 4-oxide, (R)-
3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt, 4-oxide, (7R)-
3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt, 4-oxide, (R)-
4-Hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxooctadecyl)oxy)-3,5,9-trioxa-4-phosphaheptacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)-
4-oxido de (R)-(7-lauroil-4-oxido-10-oxo-3,5,9-trioxa-4-fosfaheptacosil)trimetilamonio
4-oxyde de (R)-(7-lauroyl-4-oxydo-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium
L-DSPC
L-Distearoyllecithin
L-α-Distearoylphosphatidylcholine
L-β,γ-Distearoyl-α-lecithin
L-β,γ-Distearoyl-α-phosphatidylcholine
Choline phosphate, 3-ester with L-1,2-distearin
Choline phosphate, 3-ester with L-1,2-distearin
Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-distearin, L-
Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-distearin, L-
Coatsome MC 8080
Dioctadecanoyl-L-α-glycerophosphorylcholine
Dioctadecanoyl-L-α-glycerophosphorylcholine
Distearoyl sn-3-phosphatidylcholine
Distearoyl-L-α-glycerophosphocholine
Distearoyl-L-α-lecithin
Distearoyl-L-α-phosphatidylcholine
Distearoyl-L-α-glycerophosphocholine
Distearoyl-L-α-lecithin
Distearoyl-L-α-phosphatidylcholine
Distearoyl-sn-glycero-3-phosphocholine
Distearoylphosphatidylcholine
Dspc
L-Alpha-Phosphatidylcholine, Distearoyl
L-Distearoyllecithin
L-beta,gamma,Disteroyl-alpha-lecithin
L-α-Distearoylphosphatidylcholine
L-β,γ-Distearoyl-α-lecithin
L-β,γ-Distearoyl-α-phosphatidylcholine
Unii-043Ipi2M0K
[(2R)-2,3-Di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
β,γ-Distearoyl L-α-phosphatidylcholine
β,γ-Distearoyl L-α-phosphatidylcholine
[(2R)-2,3-distearoyloxypropyl] 2-(trimethylammonio)ethyl phosphate
L-A-PHOSPHATIDYLCHOLINE DISTEAROYL*CRYST SYNTHETIC
L-α-Phosphatidylcholine, distearoyl
18:0 PC
PC(18:0/18:0)
(R)-2,3-Bis(stearoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate
propyl (2-(trimethylammonio)
Distearoyl-L-ALPHA-phosphatidyl choline
L-BETA,GAMMA-DISTEAROYL-ALPHA-LECITHIN
-2,3-Bis(stearoyloxy)
3-sn-phosphatidylcholine, 1,2-distearoyl
1,2-Dioleoyl-sn-Glycero-3-Phsophocholine
3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin
L-A-PHOSPHATIDYLCHOLINE, DISTEAROYL
L-á-Phosphatidylcholine distearoyl
1,2-Distearoyl-sn-glycero-3-PC
[O-(1-O,2-O-Distearoyl-L-glycero-3-phospho)choline]anion
DISTEAROYL LECITHIN
1,2-Distearoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin
L-b,g-Distearoyl-a-lecithin, DSPC
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