CAS 834-28-6

cloridrato di fenformina

Descrizione:

cloridrato di fenformina è un composto farmaceutico utilizzato principalmente come agente antidiabetico, appartenente alla classe dei farmaci biguanidi. È caratterizzato dalla sua capacità di ridurre i livelli di glucosio nel sangue migliorando la sensibilità all'insulina e riducendo la produzione epatica di glucosio. Il composto è tipicamente presentato come una polvere cristallina bianca o bianco sporco, solubile in acqua e con un sapore leggermente amaro. La sua struttura chimica include un gruppo fenile, che contribuisce alle sue proprietà farmacologiche. cloridrato di fenformina è stato associato a effetti collaterali gastrointestinali e, in alcuni casi, acidosi lattica, portando al suo ritiro dal mercato in molti paesi. Nonostante il suo uso storico, è importante notare che il suo profilo di sicurezza ha sollevato preoccupazioni, spingendo allo sviluppo di farmaci alternativi con una migliore sicurezza ed efficacia. Come per qualsiasi agente farmaceutico, un dosaggio adeguato e un monitoraggio sono essenziali per minimizzare i rischi e massimizzare i benefici terapeutici.

Formula: C₁₀H₁₆ClN₅

InChI: InChI=1/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H

InChI key: InChIKey=YSUCWSWKRIOILX-UHFFFAOYSA-N

SMILES: C(CNC(NC(=N)N)=N)C1=CC=CC=C1.Cl

Sinonimi:

• 1-(2-Phenylethyl)biguanide hydrochloride
• 1-(Diaminomethylidene)-2-(2-Phenylethyl)Guanidine Hydrochloride (1:1)
• 1-Phenethylbiguanide hydrochloride
• 1-β-Phenylethylbiguanide hydrochloride
• Azucaps
• Biguanide, 1-phenethyl-, monohydrochloride
• Dbi-Td
• Debeone DT
• Debinyl
• Dibein
• Dipar
• Feguanide
• Glucopostin
• Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride (1:1)
• Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride
• Insoral
• Lentobetic
• Meltrol
• N-Phenethylbiguanide hydrochloride
• Normoglucina
• N′-β-Phenylethylbiguanide-hydrochloride
• Phenethylbiguanide hydrochloride
• Phenformin Hcl
• Phenformine HCL
• α-Phenethylbiguanide hydrochloride
• n-beta-phenylethylbiguanidehydrochloride
• 1-fenetilbiguanidecloridrato
• n’-beta-phenethylbiguanidehydrochloride
• 1-phenethyl-biguanidhydrochloride
• phenoforminehydrochloride
• phenforminhclno.9113
• PHENFORMIN HYDROCHLORIDE
• n-(2-phenylethyl)-imidodicarbonimidicdiamidmonohydrochloride
• usafvi-6
• 1-phenethyl-biguanidmonohydrochloride
• PHENFORMINI HYDROCHLORIDE
• Insora
• 1-phenylaethylbiguanidhydrochlorid

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.

Formula: C₁₀H₁₆ClN₅

Purezza: 97.11% - 99.80%

Colore e forma: White Solid

Peso molecolare: 241.72

Ref: TM-T1453

Phenformin Hydrochloride

CAS: 834-28-6

Phenformin Hydrochloride

Formula: C₁₀H₁₆ClN₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 241.72

Ref: 54-OR1014623

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride

Formula: C₁₀H₁₆ClN₅

Purezza: ≥95%

Colore e forma: Solid

Peso molecolare: 241.72

Ref: 54-BUP19681

Phenformin HCl

CAS: 834-28-6

Formula: C₁₀H₁₅N₅·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 205.27 36.46

Ref: 4Z-P-751

Phenformin Hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₅N₅·ClH

Colore e forma: White To Off-White

Peso molecolare: 241.72

Ref: 61-FOR1574.00

Phenformin Hydrochloride

Prodotto controllato

CAS: 834-28-6

Formula: C₁₀H₁₅N₅·ClH

Colore e forma: Neat

Peso molecolare: 241.72

Ref: 86-MM1574.00

Phenformin hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₅N₅·ClH

Colore e forma: Neat

Peso molecolare: 241.72

Ref: 04-C16004500

Phenformin hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₆ClN₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 241.7205

Ref: IN-DA00IDAP

Phenformin Hydrochloride

CAS: 834-28-6

Applications It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),

Formula: C₁₀H₁₅N₅·ClH

Colore e forma: Neat

Peso molecolare: 241.72

Ref: TR-P296900

Phenformin-d5 Hydrochloride

Prodotto controllato

CAS: 834-28-6

Applications Isotope labelled Phenformin It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),

Formula: C₁₀D₅H₁₀N₅·ClH

Colore e forma: Neat

Peso molecolare: 246.751

Ref: TR-P296902

Phenformin Hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₆ClN₅

Peso molecolare: 241.72

Ref: BE-BePure-24854

Phenformin Hydrochloride in Water

CAS: 834-28-6

Water

Formula: C₁₀H₁₆ClN₅

Peso molecolare: 241.72

Ref: BE-BePure-24854YW-1000

Phenformin hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₆ClN₅

Peso molecolare: 241.72

Ref: BE-RMCP128001

N-(2-phenylethyl)imidodicarbonimidic diamide hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₆ClN₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 241.72

Ref: 10-F375298

Phenformin Hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₅N₅HCl

Peso molecolare: 205.27 : 36.46

Ref: ST-EA-CP-P236000

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride is a phenformin derivative that is used as an oral hypoglycemic. It has been shown to inhibit the synthesis of fatty acids in the liver and to reduce the size of lipid droplets, which are a hallmark of hepatic steatosis. Phenformin hydrochloride also inhibits the polymerase chain reaction and mitochondrial membrane potential, which results in reduced oxidative stress and apoptosis. This drug has been shown to have anti-infectious effects against infectious diseases such as typhoid fever, tuberculosis, and malaria. Phenformin hydrochloride may also be carcinogenic, due to its ability to induce skin cancer in mice with a genetic predisposition for this type of cancer. The drug should not be administered to patients with metabolic disorders or patients who are receiving chemotherapy agents that affect cell proliferation because it can exacerbate these conditions.

Formula: C₁₀H₁₆ClN₅

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 241.72 g/mol

Ref: 3D-FP26876