CAS 84000-11-3

N-[(9H-Fluoren-9-ilmetossi)carbonil]-N-metil-L-valina

Descrizione:

N-[(9H-Fluoren-9-ilmetossi)carbonil]-N-metil-L-valina, comunemente noto come Fmoc-N-metil-L-valina, è un composto chimico ampiamente utilizzato nella sintesi di peptidi come gruppo protettore per aminoacidi. Il gruppo Fmoc, derivato dal fluorenilmetossicarbonile, fornisce stabilità durante il processo di sintesi e può essere facilmente rimosso in condizioni basiche, consentendo ulteriori reazioni. Questo composto presenta un residuo di valina, che è un aminoacido essenziale noto per le sue proprietà idrofobiche, contribuendo alle caratteristiche generali dei peptidi in cui è incorporato. La presenza del gruppo N-metil aumenta il volume sterico e può influenzare la conformazione dei peptidi risultanti. Fmoc-N-metil-L-valina è tipicamente utilizzato nella sintesi di peptidi in fase solida (SPPS), dove aiuta nell'assemblaggio selettivo delle catene peptidiche. La sua solubilità in solventi organici e stabilità in varie condizioni di reazione lo rendono un reagente prezioso nel campo della chimica organica e medicinale. Come per molte sostanze chimiche, una corretta manipolazione e precauzioni di sicurezza sono essenziali a causa dei potenziali pericoli associati al suo uso.

Formula: C₂₁H₂₃NO₄

InChI: InChI=1/C21H23NO4/c1-13(2)19(20(23)24)22(3)21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,12H2,1-3H3,(H,23,24)/t19-/m0/s1

InChI key: InChIKey=YCXXXPZNQXXRIG-IBGZPJMESA-N

SMILES: C(OC(N([C@@H](C(C)C)C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl](methyl)amino)-3-methylbutanoic acid
• (2S)-2-[9H-Fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-methylbutanoic acid
• <span class="text-smallcaps">L</span>-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• Fmoc-N-Me-Val-OH
• N-(9-Fluorenylmethoxycarbonyl)-N-methylvaline
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">L</span>-valine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine
• N-alpha-(9-fluorenylmethyloxycarbonyl)-N-alpha-Methyl-L-valine
• L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• FMOC-N-ME-VAL 98.5+%
• FMOC-L-MEVAL-OH
• FMOC-N-METHYL-L-VALINE
• FMOC-N-ALPHA-METHYL-L-VALINE
• FMOC-MEVAL-OH
• FMOC-N-ME-L-VAL-OH
• FMOC-N-ME-VALINE
• N-(9-Fluorenylmethyloxycarbonyl)-N-methyl-L-valine
• N-ALPHA(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-L-VALINE

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine

CAS: 84000-11-3

Formula: C₂₁H₂₃NO₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 353.42

Ref: 3B-F1165

N-Fmoc-N-methyl-L-valine, 95%

CAS: 84000-11-3

N-Fmoc-N-methyl-L-valine is used as enzyme substrates and reagents, culture media additives, dyes, stains and indicators. It is also involved in the preparation of N-methylated peptides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some docu

Formula: C₂₁H₂₃NO₄

Purezza: 95%

Peso molecolare: 353.42

Ref: 02-H63671

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

The acid fluoride of this sterically hindered amino acid could be coupled to N-methylated amino acids in HFIP at 55°C.

Formula: C₂₁H₂₃NO₄

Purezza: 99.7%

Colore e forma: White

Peso molecolare: 353.42

Ref: 01-4009586

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Formula: C₂₁H₂₃NO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 353.4116

Ref: IN-DA005235

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Formula: C₂₁H₂₃NO₄

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to light beige powder

Peso molecolare: 353.41

Ref: 7W-GM1535

Fmoc-N-methyl-L-valine

CAS: 84000-11-3

Fmoc-N-methyl-L-valine

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Colore e forma: white powder

Peso molecolare: 353.41g/mol

Ref: 54-OR960386

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Fmoc-N-Me-Val-OH is a modified peptide.

Formula: C₂₁H₂₃NO₄

Colore e forma: White Powder

Peso molecolare: 353.41

Ref: TM-T19325

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

M03379 - Fmoc-N-Me-Val-OH

Formula: C₂₁H₂₃NO₄

Purezza: 97%

Colore e forma: Solid, Beige powder

Peso molecolare: 353.418

Ref: 10-M03379

Fmoc-N-methyl-L-valine

CAS: 84000-11-3

Fmoc-N-methyl-L-valine is a synthetic immunosuppressant that acts by inhibiting the production of cytokines and other inflammatory mediators. It binds to the enzyme cyclooxygenase, which is involved in the synthesis of prostaglandins and thromboxanes. Fmoc-N-methyl-L-valine has been shown to be effective against gram-positive bacteria. This compound also inhibits xanthine oxidase and may act as an analog for azathioprine, which is used in the treatment of autoimmune diseases such as rheumatoid arthritis. The reaction mechanism for this compound is not well understood but appears to involve a nucleophilic attack on a benzoquinoneiminium cation formed from the attack on an electron deficient benzene ring with a triphosgene electrophile.

Formula: C₂₁H₂₃NO₄

Purezza: Min. 95%

Peso molecolare: 353.41 g/mol

Ref: 3D-FF32984